Electrochemical Deoxygenative Thiolation of Preactivated Alcohols and Ketones

This work describes an electrochemically promoted nickel-catalyzed deoxygenative thiolation of alcohols and ketones under mild conditions. Excellent substrate tolerance and good chemical yields can be achieved by graphene/nickel foam electrodes in an undivided cell. Further study to gain mechanistic insight into this electrochemical cross-coupling has been carried out.

Automated summary

This work describes a nickel-catalyzed deoxygenative thiolation of alcohols and ketones under mild conditions with electrochemical promotion. Graphene/nickel foam electrodes in an undivided cell exhibit excellent substrate tolerance and good chemical yields. Further investigation has been conducted to gain mechanistic insight into this electrochemical cross-coupling.