4.8 Letter

Empagliflozin and Major Renal Outcomes in Heart Failure

Journal

NEW ENGLAND JOURNAL OF MEDICINE
Volume 385, Issue 16, Pages 1531-1533

Publisher

MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMc2112411

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Funding

  1. Boehringer Ingelheim
  2. Eli Lilly

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Empagliflozin had different effects on renal outcomes in heart failure patients between two trials, with major adverse renal outcomes occurring in 2.8% of patients who received the drug and 3.5% of those who received a placebo.
Empagliflozin and Renal Outcomes in Heart Failure In a planned pooled analysis of two trials that evaluated empagliflozin in patients with heart failure, major adverse renal outcomes occurred in 2.8% of the patients who received empagliflozin and in 3.5% of those who received placebo. Results differed between the two trials.

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