Heparin Resistance - Clinical Perspectives and Management Strategies

Heparin Resistance Heparin resistance is suspected when more heparin than usual is needed to achieve a therapeutic range of activated partial-thromboplastin time. Management may include increasing the heparin dose, supplementing antithrombin III levels, and using direct thrombin inhibitors.

Automated summary

Heparin resistance occurs when higher doses of heparin are needed to achieve the therapeutic range of activated partial-thromboplastin time, and management may involve increasing the heparin dose, supplementing antithrombin III levels, and using direct thrombin inhibitors.