Related references
Note: Only part of the references are listed.Attenuated immune control of Epstein-Barr virus in humanized mice is associated with the multiple sclerosis risk factor HLA-DR15
Hana Zdimerova et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2021)
INPP5D expression is associated with risk for Alzheimer's disease and induced by plaque-associated microglia
Andy P. Tsai et al.
NEUROBIOLOGY OF DISEASE (2021)
Interpretation of risk loci from genome-wide association studies of Alzheimer's disease
Shea J. Andrews et al.
LANCET NEUROLOGY (2020)
Human Herpesvirus 6 Detection in Alzheimer's Disease Cases and Controls across Multiple Cohorts
Mary Alice Allnutt et al.
NEURON (2020)
Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
Julia Minderjahn et al.
NATURE COMMUNICATIONS (2020)
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region
Kai Schlepckow et al.
EMBO MOLECULAR MEDICINE (2020)
Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model
Shoutang Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia
Benjamin J. Andreone et al.
NATURE NEUROSCIENCE (2020)
Impact of TREM2R47H variant on tau pathology-induced gliosis and neurodegeneration
Maud Gratuze et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
The Alzheimer's disease-associated protective Plc gamma 2-P522R variant promotes immune functions
Mari Takalo et al.
MOLECULAR NEURODEGENERATION (2020)
Association of blood-based transcriptional risk scores with biomarkers for Alzheimer disease
Young Ho Park et al.
NEUROLOGY-GENETICS (2020)
Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease
Marta Olah et al.
NATURE COMMUNICATIONS (2020)
Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis
Maneesh K. Misra et al.
GENES AND IMMUNITY (2019)
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Brian W. Kunkle et al.
NATURE GENETICS (2019)
Alzheimer's disease phospholipase C-gamma-2 (PLCG2) protective variant is a functional hypermorph
Lorenza Magno et al.
ALZHEIMERS RESEARCH & THERAPY (2019)
Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors
Stephen S. Dominy et al.
SCIENCE ADVANCES (2019)
Evaluation of CD33 as a genetic risk factor for Alzheimer's disease
Steven Estus et al.
ACTA NEUROPATHOLOGICA (2019)
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity
Sven J. van der Lee et al.
ACTA NEUROPATHOLOGICA (2019)
TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease
Ana Griciuc et al.
NEURON (2019)
NAD+ in Brain Aging and Neurodegenerative Disorders
Sofie Lautrup et al.
CELL METABOLISM (2019)
Mapping microglia states in the human brain through the integration of high-dimensional techniques
Roman Sankowski et al.
NATURE NEUROSCIENCE (2019)
Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities
Hailan Yao et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Human stem cell-derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2
Christel Claes et al.
ALZHEIMERS & DEMENTIA (2019)
Chronic inflammation in the etiology of disease across the life span
David Furman et al.
NATURE MEDICINE (2019)
Repression of phagocytosis by human CD33 is not conserved with mouse CD33
Abhishek Bhattacherjee et al.
COMMUNICATIONS BIOLOGY (2019)
NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
Clifford R. Jack et al.
ALZHEIMERS & DEMENTIA (2018)
B-Cell Therapy for Multiple Sclerosis: Entering an Era
Ariele L. Greenfield et al.
ANNALS OF NEUROLOGY (2018)
A story of birth and death: Insights into the formation and dynamics of the microglial population
Katharine Askew et al.
BRAIN BEHAVIOR AND IMMUNITY (2018)
Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2
Athena Sudom et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain
Diego Mastroeni et al.
NEUROBIOLOGY OF AGING (2018)
Extravascular CD3+T Cells in Brains of Alzheimer Disease Patients Correlate with Tau but Not with Amyloid Pathology: An Immunohistochemical Study
Mario Merlini et al.
NEURODEGENERATIVE DISEASES (2018)
Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models
C. Y. Daniel Lee et al.
NEURON (2018)
Alzheimer's Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection
William A. Eimer et al.
NEURON (2018)
Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
Ben Readhead et al.
NEURON (2018)
A transcriptomic atlas of aged human microglia
Marta Olah et al.
NATURE COMMUNICATIONS (2018)
GWAS on family history of Alzheimer's disease
Riccardo E. Marioni et al.
TRANSLATIONAL PSYCHIATRY (2018)
The Role of Phospholipase C Signaling in Macrophage-Mediated Inflammatory Response
Liqian Zhu et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2018)
PU.1 regulates Alzheimer's disease-associated genes in primary human microglia
Justin Rustenhoven et al.
MOLECULAR NEURODEGENERATION (2018)
Innate immune memory in the brain shapes neurological disease hallmarks
Ann-Christin Wendeln et al.
NATURE (2018)
Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy
Faten A. Sayed et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Microglial TREM2/DAP12 Signaling: A Double-Edged Sword in Neural Diseases
Hiroyuki Konishi et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2018)
Systemic infection modifies the neuroinflammatory response in late stage Alzheimer's disease
Sonja Rakic et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)
Microglia and the Brain: Complementary Partners in Development and Disease
Timothy R. Hammond et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 34 (2018)
Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease
Nisha Rathore et al.
PLOS GENETICS (2018)
Amyloid, tau, pathogen infection and antimicrobial protection in Alzheimer's disease -conformist, nonconformist, and realistic prospects for AD pathogenesis
Hongmei Li et al.
TRANSLATIONAL NEURODEGENERATION (2018)
Nicotinamide adenine dinucleotide and its related precursors for the treatment of Alzheimer's disease
Nady Braidy et al.
CURRENT OPINION IN PSYCHIATRY (2018)
Repression of telomere-associated genes by microglia activation in neuropsychiatric disease
Golo Kronenberg et al.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2017)
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Rebecca Sims et al.
NATURE GENETICS (2017)
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease
Kuan-lin Huang et al.
NATURE NEUROSCIENCE (2017)
Location, Location, Location: Microglia Are Where They Live
Margaret M. McCarthy
NEURON (2017)
TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy
Cheryl E. G. Leyns et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
The Lifespan and Turnover of Microglia in the Human Brain
Pedro Reu et al.
CELL REPORTS (2017)
Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution
Hansruedi Mathys et al.
CELL REPORTS (2017)
Studies on Colony Stimulating Factor Receptor-1 and Ligands Colony Stimulating Factor-1 and Interleukin-34 in Alzheimer's Disease Brains and Human Microglia
Douglas G. Walker et al.
FRONTIERS IN AGING NEUROSCIENCE (2017)
Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study
Natasha Z. R. Steele et al.
PLOS MEDICINE (2017)
Chronic inflammation in immune Aging: Role of Pattern Recognition Receptor Crosstalk with the Telomere Complex?
Shyam Sushama Jose et al.
FRONTIERS IN IMMUNOLOGY (2017)
Fighting against a protean enemy: immunosenescence, vaccines, and healthy aging
Giuseppe Del Giudice et al.
NPJ AGING AND MECHANISMS OF DISEASE (2017)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Hadas Keren-Shaul et al.
CELL (2017)
Human-specific derived alleles of CD33 and other genes protect against postreproductive cognitive decline
Flavio Schwarz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Cerebrospinal fluid soluble TREM2 is higher in Alzheimer disease and associated with mutation status
Laura Piccio et al.
ACTA NEUROPATHOLOGICA (2016)
TREM1 facilitates microglial phagocytosis of amyloid beta
Teng Jiang et al.
ACTA NEUROPATHOLOGICA (2016)
Why NAD+ Declines during Aging: It's Destroyed
Michael B. Schultz et al.
CELL METABOLISM (2016)
TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques
Yaming Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Disease Progression-Dependent Effects of TREM2 Deficiency in a Mouse Model of Alzheimer's Disease
Taylor R. Jay et al.
JOURNAL OF NEUROSCIENCE (2016)
The silent war of CMV in aging and HIV infection
Rita B. Effros
MECHANISMS OF AGEING AND DEVELOPMENT (2016)
Assessment of the genetic variance of late-onset Alzheimer's disease
Perry G. Ridge et al.
NEUROBIOLOGY OF AGING (2016)
TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy
Peng Yuan et al.
NEURON (2016)
GM-CSF Down-Regulates TLR Expression via the Transcription Factor PU.1 in Human Monocytes
Kambis Sadeghi et al.
PLOS ONE (2016)
Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease
Deepak Kumar Vijaya Kumar et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms
Daniel L. Kober et al.
ELIFE (2016)
The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease
Christina M. Lill et al.
ALZHEIMERS & DEMENTIA (2015)
A TREM1 Variant Alters the Accumulation of Alzheimer-Related Amyloid Pathology
Joseph M. Replogle et al.
ANNALS OF NEUROLOGY (2015)
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer's Disease Model
Yaming Wang et al.
CELL (2015)
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke
Masahito Kawabori et al.
JOURNAL OF NEUROSCIENCE (2015)
CD33 modulates TREM2: convergence of Alzheimer loci
Gail Chan et al.
NATURE NEUROSCIENCE (2015)
Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex
Douglas G. Walke et al.
NEUROBIOLOGY OF AGING (2015)
Connecting Two Pathways Through Ca2+ Signaling: NLRP3 Inflammasome Activation Induced by a Hypermorphic PLCG2 Mutation
Jae Jin Chae et al.
ARTHRITIS & RHEUMATOLOGY (2015)
Homeostatic and injury-induced microglia behavior in the aging brain
Jasmin K. Hefendehl et al.
AGING CELL (2014)
Microglial dysfunction in brain aging and Alzheimer's disease
Kira Irving Mosher et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Chronic Inflammatory Disorders and Risk of Type 2 Diabetes Mellitus, Coronary Heart Disease, and Stroke A Population-Based Cohort Study
Alex Dregan et al.
CIRCULATION (2014)
Complexities in the Relationship Between Infection and Autoimmunity
Robert Root-Bernstein et al.
CURRENT ALLERGY AND ASTHMA REPORTS (2014)
CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimers disease susceptibility
Towfique Raj et al.
HUMAN MOLECULAR GENETICS (2014)
Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1)-mediated Bcl-2 Induction Prolongs Macrophage Survival
Zhihong Yuan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Negative Regulation of Toll-like Receptor-4 Signaling through the Binding of Glycosylphosphatidylinositol-anchored Glycoprotein, CD14, with the Sialic Acid-binding Lectin, CD33
Akiko Ishida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia
Tijmen J. Hommes et al.
JOURNAL OF PATHOLOGY (2014)
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
Mike A. Nalls et al.
NATURE GENETICS (2014)
Alzheimer's Associated β-Amyloid Protein Inhibits Influenza A Virus and Modulates Viral Interactions with Phagocytes
Mitchell R. White et al.
PLOS ONE (2014)
TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
Gernot Kleinberger et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Microglia Modulate Wiring of the Embryonic Forebrain
Paola Squarzoni et al.
CELL REPORTS (2014)
Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region
William T. Wissemann et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Activation of Triggering Receptor Expressed on Myeloid Cells-1 Protects Monocyte from Apoptosis through Regulation of Myeloid Cell Leukemia-1
MeiTing Cai et al.
ANESTHESIOLOGY (2013)
Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer's Disease
Bin Zhang et al.
CELL (2013)
Can Infections Cause Alzheimer's Disease?
Francis Ellawanda et al.
EPIDEMIOLOGIC REVIEWS (2013)
Induction of myelodysplasia by myeloid-derived suppressor cells
Xianghong Chen et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival
Jian Luo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
TREM-1: intracellular signaling pathways and interaction with pattern recognition receptors
Rob J. W. Arts et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2013)
CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing
Manasi Malik et al.
JOURNAL OF NEUROSCIENCE (2013)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2013)
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology
Elizabeth M. Bradshaw et al.
NATURE NEUROSCIENCE (2013)
Alzheimer's Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
Ana Griciuc et al.
NEURON (2013)
Variant of TREM2 Associated with the Risk of Alzheimer's Disease
Thorlakur Jonsson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
TREM2 Variants in Alzheimer's Disease
Rita Guerreiro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Attenuated Inflammatory Response in Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Knock-Out Mice following Stroke
Matthias W. Sieber et al.
PLOS ONE (2013)
Origin and differentiation of microglia
Florent Ginhoux et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2013)
Evidence for impaired amyloid beta clearance in Alzheimer's disease
Kristin R. Wildsmith et al.
ALZHEIMERS RESEARCH & THERAPY (2013)
A Hypermorphic Missense Mutation in PLCG2, Encoding Phospholipase Cγ2, Causes a Dominantly Inherited Autoinflammatory Disease with Immunodeficiency
Qing Zhou et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2012)
Mechanisms of Amyloid-β Peptide Clearance: Potential Therapeutic Targets for Alzheimer's Disease
Sang-Sun Yoon et al.
BIOMOLECULES & THERAPEUTICS (2012)
Autoimmune heart disease: role of sex hormones and autoantibodies in disease pathogenesis
DeLisa Fairweather et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2012)
Phospholipase Cγ-2 and Intracellular Calcium Are Required for Lipopolysaccharide-induced Toll-like Receptor 4 (TLR4) Endocytosis and Interferon Regulatory Factor 3 (IRF3) Activation
Chih-Yuan Chiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages
Guillaume Hoeffel et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia
Yaming Wang et al.
NATURE IMMUNOLOGY (2012)
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
Dorothy P. Schafer et al.
NEURON (2012)
TGF-β induced by interleukin-34-stimulated microglia regulates microglial proliferation and attenuates oligomeric amyloid β neurotoxicity
Di Ma et al.
NEUROSCIENCE LETTERS (2012)
Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
Randall J. Bateman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
Christian Schulz et al.
SCIENCE (2012)
Herpesvirus Exploitation of Host Immune Inhibitory Pathways
Gabrielle Stack et al.
VIRUSES-BASEL (2012)
Age-related alterations in the dynamic behavior of microglia
Mausam R. Damani et al.
AGING CELL (2011)
National estimates of the prevalence of Alzheimer's disease in the United States
Ron Brookmeyer et al.
ALZHEIMERS & DEMENTIA (2011)
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Reisa A. Sperling et al.
ALZHEIMERS & DEMENTIA (2011)
Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity
Tetsuya Mizuno et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Epitope mapping, expression and post-translational modifications of two isoforms of CD33 (CD33M and CD33m) on lymphoid and myeloid human cells
Ana B. Perez-Oliva et al.
GLYCOBIOLOGY (2011)
Evolution of CD33-related siglecs: regulating host immune functions and escaping pathogen exploitation?
Huan Cao et al.
IMMUNOLOGY (2011)
Alzheimer's disease genetics: current knowledge and future challenges
Paul Hollingworth et al.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY (2011)
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
Adam C. Naj et al.
NATURE GENETICS (2011)
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
Paul Hollingworth et al.
NATURE GENETICS (2011)
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
Jean -Philippe Coppe et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways
P. Prieto et al.
CELL DEATH AND DIFFERENTIATION (2010)
Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease
Sudha Seshadri et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2010)
Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells
Suwen Wei et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2010)
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
Taye H. Hamza et al.
NATURE GENETICS (2010)
The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide
Stephanie J. Soscia et al.
PLOS ONE (2010)
Decreased Clearance of CNS β-Amyloid in Alzheimer's Disease
Kwasi G. Mawuenyega et al.
SCIENCE (2010)
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
Florent Ginhoux et al.
SCIENCE (2010)
TREM2-and DAP12-Dependent Activation of PI3K Requires DAP10 and Is Inhibited by SHIP1
Qisheng Peng et al.
SCIENCE SIGNALING (2010)
Classification and basic pathology of Alzheimer disease
Charles Duyckaerts et al.
ACTA NEUROPATHOLOGICA (2009)
Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy
Justin Zaghi et al.
ACTA NEUROPATHOLOGICA (2009)
DAP10-and DAP12-associated receptors in innate immunity
Lewis L. Lanier
IMMUNOLOGICAL REVIEWS (2009)
Immune blood biomarkers of Alzheimer disease patients
Hripsime Avagyan et al.
JOURNAL OF NEUROIMMUNOLOGY (2009)
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2009)
Genome-wide Association Analysis Reveals Putative Alzheimer's Disease Susceptibility Loci in Addition to APOE
Lars Bertram et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Siglecs as positive and negative regulators of the immune system
Paul R. Crocker et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2008)
PILRα is a herpes simplex virus-1 entry coreceptor that associates with glycoprotein B
Takeshi Satoh et al.
CELL (2008)
From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection
Omar Sharif et al.
IMMUNOBIOLOGY (2008)
Innate immune responses to TREM-1 activation: Overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide
Ken Dower et al.
JOURNAL OF IMMUNOLOGY (2008)
Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice
Suzanne E. Hickman et al.
JOURNAL OF NEUROSCIENCE (2008)
Discovery of a cytokine and its receptor by functional screening of the extracellular proteome
Haishan Lin et al.
SCIENCE (2008)
Phosphorylated ITIMs enable ubiquitylation of an inhibitory cell surface receptor
Roland B. Walter et al.
TRAFFIC (2008)
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
Uwe-Karsten Hanisch et al.
NATURE NEUROSCIENCE (2007)
Transcriptional control of granulocyte and monocyte development
A. D. Friedman
ONCOGENE (2007)
TREM-1 expression in macrophages is regulated at transcriptional level by NF-κB and PU.1
Heng Zeng et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
PU.1 activates transcription of SHP-1 gene in hematopoietic cells
Pawel Wlodarski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover
Selinda J. Orr et al.
BLOOD (2007)
TREM-1 promotes survival during septic shock in mice
Sebastien Gibot et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Siglecs and their roles in the immune system
Paul R. Crocker et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Mechanisms of disease: astrocytes in neurodegenerative disease
Nicholas J. Maragakis et al.
NATURE CLINICAL PRACTICE NEUROLOGY (2006)
Cutting edge: TREM-2 attenuates macrophage activation
Isaiah R. Turnbull et al.
JOURNAL OF IMMUNOLOGY (2006)
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis
Lisa F. Barcellos et al.
HUMAN MOLECULAR GENETICS (2006)
Cutting edge: Inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12
Jessica A. Hamerman et al.
JOURNAL OF IMMUNOLOGY (2006)
Colony-stimulating factor-1 in immunity and inflammation
V Chitu et al.
CURRENT OPINION IN IMMUNOLOGY (2006)
Microglial senescence: does the brain's immune system have an expiration date?
Wolfgang J. Streit
TRENDS IN NEUROSCIENCES (2006)
Human immunosenescence: is it infectious?
G Pawelec et al.
IMMUNOLOGICAL REVIEWS (2005)
Ineffective phagocytosis of amyloid-β by macrophages of Alzheimer's disease patients
M Fiala et al.
JOURNAL OF ALZHEIMERS DISEASE (2005)
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
A Nimmerjahn et al.
SCIENCE (2005)
PU.1 regulates the commitment of adult hematopoietic progenitors and restricts granulopoiesis
A Dakic et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
K Takahashi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Meta-analysis of nonsteroidal antiinflammatory drug use and risk of dementia
AJM de Craen et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2005)
Constitutive repressor activity of CD33 on human monocytes requires sialic acid recognition and phosphoinositide 3-kinase-mediated intracellular signaling
F Lajaunias et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2005)
A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response
JR Bleharski et al.
JOURNAL OF IMMUNOLOGY (2003)
Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
XM Dai et al.
BLOOD (2002)
Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease
BA in 't Veld et al.
NEW ENGLAND JOURNAL OF MEDICINE (2001)
A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells
A Bouchon et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Inflammation and Alzheimer's disease
H Akiyama et al.
NEUROBIOLOGY OF AGING (2000)
PU.1 and interferon consensus sequence-binding protein regulate the myeloid expression of the human toll-like receptor 4 gene
M Rehli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
