4.7 Review

Evolution of glutamatergic signaling and synapses

Related references

Note: Only part of the references are listed.
Review Neurosciences

Glutamate receptors from diverse animal species exhibit unexpected structural and functional diversity

Mark L. Mayer

Summary: The research by Watkins and colleagues has played a crucial role in our understanding of excitatory synaptic transmission in the central nervous system of animals; recent studies have revealed unexpected ligand binding profiles for newly identified glutamate receptors; structural studies indicate that the biology of glutamate receptors is more complex than initially anticipated.

JOURNAL OF PHYSIOLOGY-LONDON (2021)

Article Geochemistry & Geophysics

Extraterrestrial amino acids and L-enantiomeric excesses in the CM2 carbonaceous chondrites Aguas Zarcas and Murchison

Daniel P. Glavin et al.

Summary: By studying the amino acids in the Aguas Zarcas and Murchison meteorites, it is revealed that they preferentially enriched L-amino acids during the early formation of the solar system and the extent of contamination by Earth.

METEORITICS & PLANETARY SCIENCE (2021)

Article Developmental Biology

The tubulin code specializes neuronal cilia for extracellular vesicle release

Jyothi S. Akella et al.

Summary: This review highlights the diversity of ciliary microtubules in C. elegans sensory neurons and the mechanisms driving the specialization of neurons releasing extracellular vesicles. It emphasizes the importance of distinct axonemal features and specialized intraflagellar transport for the release of EVs. Additionally, the role of the tubulin code in ciliary specialization is discussed.

DEVELOPMENTAL NEUROBIOLOGY (2021)

Article Biophysics

Potassium Glutamate and Glycine Betaine Induce Self-Assembly of the PCNA and β-Sliding Clamps

Anirban Purohit et al.

Summary: It has been found that non-Coulombic ionic effects have an impact on the oligomerization properties of sliding clamps, and replacing NaCl with KGIu in E. coli results in a decrease in the diffusion coefficient of proteins, leading to the formation of protein assemblies. The study also shows that KGIu induces the formation of assemblies involving two or more rings stacked face-to-face.

BIOPHYSICAL JOURNAL (2021)

Review Neurosciences

Single-Cell Sequencing of Brain Cell Transcriptomes and Epigenomes

Ethan J. Armand et al.

Summary: Single-cell sequencing technologies provide insights into the diversity and developmental relationships of brain cell types, aiding in the design of tools for targeted functional studies of brain circuit components.

NEURON (2021)

Editorial Material Biochemistry & Molecular Biology

Animal Phylogeny: Resolving the Slugfest of Ctenophores, Sponges and Acoels?

Gaspar Jekely et al.

Summary: The study provides some much-needed order for the controversial animal phylogeny, specifically focusing on the ctenophores and Xenacoelomorphs. It introduces an innovative approach to dissect systematic errors in molecular phylogenies, aiming to improve the underlying methodology.

CURRENT BIOLOGY (2021)

Review Biology

Neural versus alternative integrative systems: molecular insights into origins of neurotransmitters

Leonid L. Moroz et al.

Summary: Transmitter signalling is the universal chemical language of the nervous system, with origins possibly in secretory cells capable of volume chemical transmission and behavior integration. Different neurotransmitters may have been recruited relatively early or late in animal evolution.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2021)

Article Biology

The chemical brain hypothesis for the origin of nervous systems

Gaspar Jekely

Summary: In nervous systems, activity propagation between cells occurs through synaptic transmission and volume transmission. Research suggests that chemically organized cellular networks may have appeared before synapses in evolution. Peptidergic signaling, facilitated by small peptides, played a key role in wiring cells into chemical networks. The development of circulatory systems and neurohemal organs further enhanced the efficiency of chemical signaling, contributing to the explosive radiation of peptidergic signaling systems in stem bilaterians.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2021)

Article Biochemistry & Molecular Biology

The tree of life describes a tripartite cellular world

Arshan Nasir et al.

Summary: This article revisits the debate between the 3-domain tree and the 2-domain tree, highlighting the limitations of alignment-dependent methods and the advantages of alignment-free methodologies. The authors argue that the discoveries of Asgards and ESPs do not completely rule out the 3D tree, which is supported by genomic analyses.

BIOESSAYS (2021)

Article Biochemistry & Molecular Biology

A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation

Zizhen Yao et al.

Summary: This study provides a comprehensive analysis of cell types in the mammalian isocortex and hippocampal formation, revealing a shared neural circuit organization between the two structures. The research also uncovers large-scale variations in cell types along different dimensions within these brain regions.
Review Biochemical Research Methods

TCA cycle signalling and the evolution of eukaryotes

Dylan G. Ryan et al.

Summary: The origin of eukaryotic cell complexity is believed to have emerged from the symbiosis between a proteobacterium and an archaeal host, with contributions from the mitochondrial genome and archaeal histones. Evolutionary communication between the host and symbiont remains unclear, while mitochondrial TCA cycle signaling is proposed to play a crucial role in controlling genome expansion. TCA cycle remodeling serves as an evolutionary strategy for eukaryotic organisms to coordinate stress responses and gene expression, with itaconate as a focus.

CURRENT OPINION IN BIOTECHNOLOGY (2021)

Article Multidisciplinary Sciences

Expanded diversity of Asgard archaea and their relationships with eukaryotes

Yang Liu et al.

Summary: Research on Asgard archaea suggests that the origin of eukaryotes may be within or outside Asgard, with phylogenomic analysis unable to provide a clear answer. The study introduces six new phyla and demonstrates an expansion of eukaryotic signature proteins, indicating a dynamic evolutionary process.

NATURE (2021)

Article Multidisciplinary Sciences

Signal transduction through Cys-loop receptors is mediated by the nonspecific bumping of closely apposed domains

Gisela D. Cymes et al.

Summary: In Cys-loop receptors, the gating of ion channels does not depend on the conservation of sequence or physicochemical properties across the extracellular-transmembrane-domain interface. Instead, proper gating requires the overall structure of the interfacial loops to be conserved, with the relative orientation and distance appropriate for changes in one side to result in changes in the other, akin to the nonspecific bumping of closely apposed domains.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

Article Multidisciplinary Sciences

Evidence for sponges as sister to all other animals from partitioned phylogenomics with mixture models and recoding

Anthony K. Redmond et al.

Summary: This study demonstrates significant progress in partitioned phylogenomic analysis by using site-heterogeneous models and amino acid recoding to alleviate branching artefacts caused by systematic errors. The reanalysis of key datasets shows that partitioned phylogenomics does not support comb jellies as sister to other animals. Branching artefacts can confound the reconstruction of deep evolutionary relationships.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Lack of support for Deuterostomia prompts reinterpretation of the first Bilateria

Paschalia Kapli et al.

Summary: Bilaterally symmetric animals are divided into Protostomia and Deuterostomia, with Protostomia consistently receiving strong support in phylogenetic studies. However, support for Deuterostomia is equivocal and may be influenced by systematic errors, suggesting that the common ancestor of bilaterians and deuterostomes may have been deuterostome-like.

SCIENCE ADVANCES (2021)

Article Biochemistry & Molecular Biology

Rooting the Animal Tree of Life

Yuanning Li et al.

Summary: This study examines the debate over whether sponges or comb jellies are the most distant animal relatives, with a focus on the extensive differences in analyses that have led to inconsistent results. By synthesizing previous studies and conducting new analyses under standardized conditions, it is found that the recovery of comb jellies as the most distant relatives is consistent across various conditions, while sponges are recovered under specific conditions with the use of site-heterogeneous CAT models. The study also highlights the skepticism that should be applied to sponge-sister results due to the narrow conditions in which they are recovered and the lack of significant fit compared to other models recovering comb jelly-sister.

MOLECULAR BIOLOGY AND EVOLUTION (2021)

Review Neurosciences

Structural biology of kainate receptors

Mark L. Mayer

Summary: This review summarizes structural studies on kainate receptors, explaining their unique functional properties. Insights into the key role mechanisms in assembly of kainate receptors have been revealed through various structures and biochemical studies. Additionally, novel structures for the desensitized state of homomeric and heteromeric kainate receptors have been discovered, differing significantly from AMPA receptors.

NEUROPHARMACOLOGY (2021)

Review Neurosciences

Glycine agonism in ionotropic glutamate receptors

David Stroebel et al.

Summary: Ionotropic glutamate receptors (iGluRs) are essential for excitatory neurotransmission in the vertebrate CNS and play a major role in learning and memory. Some iGluR subunits do not bind glutamate, but instead bind glycine and D-serine, which have different roles and affinities in various subtypes of glycinergic iGluRs. Glycine and D-serine influence the activity and function of iGluRs, reshaping our understanding of their signaling diversity and complexity in neuropharmacology.

NEUROPHARMACOLOGY (2021)

Review Neurosciences

Metazoan evolution and diversity of glutamate receptors and their auxiliary subunits

David Ramos-Vicente et al.

Summary: Glutamate is the major excitatory neurotransmitter in both vertebrate and invertebrate nervous systems. The evolution of glutamate receptors is more complex than anticipated, with recent research proposing a new classification system for ionotropic glutamate receptors. Additionally, the evolution of animal metabotropic glutamate receptors has resulted in the formation of four classes instead of three previously recognized.

NEUROPHARMACOLOGY (2021)

Article Multidisciplinary Sciences

The American lobster genome reveals insights on longevity, neural, and immune adaptations

Jennifer M. Polinski et al.

Summary: The American lobster plays a crucial role in marine ecosystems and supports commercial fishing. It serves as a valuable model for studying neural networks and olfaction, with complex chemosensory and defense mechanisms contributing to its longevity and ecological success in the marine environment.

SCIENCE ADVANCES (2021)

Article Cell Biology

Selective Advantages of Synapses in Evolution

Leonid L. Moroz et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Exogenous Treatment with Glutamate Induces Immune Responses in Arabidopsis

Yukihisa Goto et al.

MOLECULAR PLANT-MICROBE INTERACTIONS (2020)

Article Multidisciplinary Sciences

The structural bases for agonist diversity in an Arabidopsis thaliana glutamate receptor-like channel

Andrea Alfieri et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Multidisciplinary Sciences

Mitochondrial TCA cycle metabolites control physiology and disease

Inmaculada Martinez-Reyes et al.

NATURE COMMUNICATIONS (2020)

Article Biochemistry & Molecular Biology

Microchemical identification of enantiomers in early-branching animals: Lineage-specific diversification in the usage of D-glutamate and D-aspartate

Leonid L. Moroz et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

Editorial Material Biochemistry & Molecular Biology

Cultured Asgard Archaea Shed Light on Eukaryogenesis

Purificacion Lopez-Garcia et al.

Article Multidisciplinary Sciences

Tubulin tails and their modifications regulate protein diffusion on microtubules

Lavi S. Bigman et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Microbiology

Cyclic di-AMP Signaling in Bacteria

Joerg Stuelke et al.

ANNUAL REVIEW OF MICROBIOLOGY, VOL 74, 2020 (2020)

Review Microbiology

Older Than Genes: The Acetyl CoA Pathway and Origins

William F. Martin

FRONTIERS IN MICROBIOLOGY (2020)

Article Biochemistry & Molecular Biology

Sodium action potentials in placozoa: Insights into behavioral integration and evolution of nerveless animals

Daria Y. Romanova et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

Article Developmental Biology

Binary fission in Trichoplax is orthogonal to the subsequent division plane

Jorge Zuccolotto-Arellano et al.

MECHANISMS OF DEVELOPMENT (2020)

Article Biochemistry & Molecular Biology

Structural basis for polyglutamate chain initiation and elongation by TTLL family enzymes

Kishore K. Mahalingan et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)

Article Biochemistry & Molecular Biology

New Lineage of Microbial Predators Adds Complexity to Reconstructing the Evolutionary Origin of Animals

Denis Tikhonenkov et al.

CURRENT BIOLOGY (2020)

Editorial Material Chemistry, Multidisciplinary

Prebiotic metabolism gets a boost

Albert C. Fahrenbach et al.

NATURE CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

A plausible metal-free ancestral analogue of the Krebs cycle composed entirely of α-ketoacids

R. Trent Stubbs et al.

NATURE CHEMISTRY (2020)

Article Plant Sciences

Glutamate-Induced Electrical and Calcium Signals in the Moss Physcomitrella patens

Mateusz Koselski et al.

PLANT AND CELL PHYSIOLOGY (2020)

Review Plant Sciences

The Lifecycle of the Plant Immune System

Pai Li et al.

CRITICAL REVIEWS IN PLANT SCIENCES (2020)

Review Chemistry, Multidisciplinary

When Did Life Likely Emerge on Earth in an RNA-First Process?

Steven A. Benner et al.

CHEMSYSTEMSCHEM (2020)

Article Multidisciplinary Sciences

Synthesis and breakdown of universal metabolic precursors promoted by iron

Kamila B. Muchowska et al.

NATURE (2019)

Article Multidisciplinary Sciences

Coherent directed movement toward food modeled in Trichoplax, a ciliated animal lacking a nervous system

Carolyn L. Smith et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Multidisciplinary Sciences

Bacteria push the limits of chemotactic precision to navigate dynamic chemical gradients

Douglas R. Brumley et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Cell Biology

Insights into the evolution of digestive systems from studies of Trichoplax adhaerens

Carolyn L. Smith et al.

CELL AND TISSUE RESEARCH (2019)

Review Biochemistry & Molecular Biology

The energetic brain - A review from students to students

Melina Paula Bordone et al.

JOURNAL OF NEUROCHEMISTRY (2019)

Article Biology

Metabolic basis of brain-like electrical signalling in bacterial communities

Rosa Martinez-Corral et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2019)

Article Multidisciplinary Sciences

Stem cell differentiation trajectories in Hydra resolved at single-cell resolution

Stefan Siebert et al.

SCIENCE (2019)

Editorial Material Microbiology

Eukaryogenesis, a syntrophy affair

Purificacion Lopez-Garcia et al.

NATURE MICROBIOLOGY (2019)

Editorial Material Biology

Evolution of mechanisms and behaviour important for pain

Edgar T. Walters et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2019)

Article Chemistry, Multidisciplinary

Counting the Number of Glutamate Molecules in Single Synaptic Vesicles

Yuanmo Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Ecology

Social Feeding Behavior of Trichoplax adhaerens

Angelo Fortunato et al.

FRONTIERS IN ECOLOGY AND EVOLUTION (2019)

Review Endocrinology & Metabolism

Coupling Krebs cycle metabolites to signalling in immunity and cancer

Dylan G. Ryan et al.

NATURE METABOLISM (2019)

Article Biochemistry & Molecular Biology

NeuroSystematics and Periodic System of Neurons: Model vs Reference Species at Single-Cell Resolution

Leonid L. Moroz

ACS CHEMICAL NEUROSCIENCE (2018)

Review Plant Sciences

Comparing plant and animal glutamate receptors: common traits but different fates?

Michael M. Wudick et al.

JOURNAL OF EXPERIMENTAL BOTANY (2018)

Article Multidisciplinary Sciences

Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation

Haidai Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Multidisciplinary Sciences

A primordial and reversible TCA cycle in a facultatively chemolithoautotrophic thermophile

Takuro Nunoura et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway

Yoshishige Kimura et al.

SCIENTIFIC REPORTS (2018)

Article Multidisciplinary Sciences

Developmental diversification of cortical inhibitory interneurons

Christian Mayer et al.

NATURE (2018)

Article Multidisciplinary Sciences

Bistable emergence of oscillations in growing Bacillus subtilis biofilms

Rosa Martinez-Corral et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Editorial Material Multidisciplinary Sciences

Nervous system-like signaling in plant defense

Gloria K. Muday et al.

SCIENCE (2018)

Article Multidisciplinary Sciences

Glutamate triggers long-distance, calcium-based plant defense signaling

Masatsugu Toyota et al.

SCIENCE (2018)

Article Biochemistry & Molecular Biology

The mammalian decidual cell evolved from a cellular stress response

Eric M. Erkenbrack et al.

PLOS BIOLOGY (2018)

Article Biochemistry & Molecular Biology

High Cell Diversity and Complex Peptidergic Signaling Underlie Placozoan Behavior

Frederique Varoqueaux et al.

CURRENT BIOLOGY (2018)

Article Multidisciplinary Sciences

Shared and distinct transcriptomic cell types across neocortical areas

Bosiljka Tasic et al.

NATURE (2018)

Article Multidisciplinary Sciences

Ultrafast epithelial contractions provide insights into contraction speed limits and tissue integrity

Shahaf Armon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Biology

Neuropeptidergic integration of behavior in Trichoplax adhaerens, an animal without synapses

Adriano Senatore et al.

JOURNAL OF EXPERIMENTAL BIOLOGY (2017)

Article Biochemistry & Molecular Biology

Glutamate promotes SSB protein-protein Interactions via intrinsically disordered regions

Alexander G. Kozlov et al.

JOURNAL OF MOLECULAR BIOLOGY (2017)

Article Multidisciplinary Sciences

GLUTAMATE RECEPTOR-LIKE channels are essential for chemotaxis and reproduction in mosses

Carlos Ortiz-Ramirez et al.

NATURE (2017)

Article Multidisciplinary Sciences

Asgard archaea illuminate the origin of eukaryotic cellular complexity

Katarzyna Zaremba-Niedzwiedzka et al.

NATURE (2017)

Article Multidisciplinary Sciences

Coupling between distant biofilms and emergence of nutrient time-sharing

Jintao Liu et al.

SCIENCE (2017)

Review Neurosciences

Back to the Basics: Cnidarians Start to Fire

Thomas C. G. Bosch et al.

TRENDS IN NEUROSCIENCES (2017)

Article Ecology

Ctenophore relationships and their placement as the sister group to all other animals

Nathan V. Whelan et al.

NATURE ECOLOGY & EVOLUTION (2017)

Review Cell Biology

The Origin of Animal Multicellularity and Cell Differentiation

Thibaut Brunet et al.

DEVELOPMENTAL CELL (2017)

Review Biotechnology & Applied Microbiology

The many roles of glutamate in metabolism

Mark C. Walker et al.

JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY (2016)

Article Plant Sciences

Glutamate functions in stomatal closure in Arabidopsis and fava bean

Riichiro Yoshida et al.

JOURNAL OF PLANT RESEARCH (2016)

Review Biology

Independent origins of neurons and synapses: insights from ctenophores

Leonid L. Moroz et al.

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2016)

Article Cell Biology

A pathway map of glutamate metabolism

Soujanya D. Yelamanchi et al.

JOURNAL OF CELL COMMUNICATION AND SIGNALING (2016)

Article Biochemistry & Molecular Biology

Evolutionary insight into the ionotropic glutamate receptor superfamily of photosynthetic organisms

Sara De Bortoli et al.

BIOPHYSICAL CHEMISTRY (2016)

Article Biochemistry & Molecular Biology

An updated structural classification of substrate-binding proteins

Giel H. Scheepers et al.

FEBS LETTERS (2016)

Article Multidisciplinary Sciences

New deep-sea species of Xenoturbella and the position of Xenacoelomorpha

Greg W. Rouse et al.

NATURE (2016)

Editorial Material Multidisciplinary Sciences

PHYLOGENY A home for Xenoturbella

Henry Gee

NATURE (2016)

Editorial Material Multidisciplinary Sciences

Evolution A sisterly dispute

Maximilian J. Telford

NATURE (2016)

Article Multidisciplinary Sciences

Xenacoelomorpha is the sister group to Nephrozoa

Johanna Taylor Cannon et al.

NATURE (2016)

Article Biochemistry & Molecular Biology

Metabolite concentrations, fluxes and free energies imply efficient enzyme usage

Junyoung O. Park et al.

NATURE CHEMICAL BIOLOGY (2016)

Review Microbiology

Biofilms: an emergent form of bacterial life

Hans-Curt Flemming et al.

NATURE REVIEWS MICROBIOLOGY (2016)

Letter Multidisciplinary Sciences

Miscues misplace sponges

Kenneth M. Halanych et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Molecular lock regulates binding of glycine to a primitive NMDA receptor

Alvin Yu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Recognition of enzymes lacking bound cofactor by protein quality control

Adrian Martinez-Limon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Evolution of Pentameric Ligand-Gated Ion Channels: Pro-Loop Receptors

Mariama Jaiteh et al.

PLOS ONE (2016)

Review Biology

Evolution of voltage-gated ion channels at the emergence of Metazoa

Yehu Moran et al.

JOURNAL OF EXPERIMENTAL BIOLOGY (2015)

Review Biology

Convergent evolution of neural systems in ctenophores

Leonid L. Moroz

JOURNAL OF EXPERIMENTAL BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Relation between chemotaxis and consumption of amino acids in bacteria

Yiling Yang et al.

MOLECULAR MICROBIOLOGY (2015)

Article Multidisciplinary Sciences

Metabolic co-dependence gives rise to collective oscillations within biofilms

Jintao Liu et al.

NATURE (2015)

Article Multidisciplinary Sciences

Ion channels enable electrical communication in bacterial communities

Arthur Prindle et al.

NATURE (2015)

Article Chemistry, Multidisciplinary

Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism

Bhavesh H. Patel et al.

NATURE CHEMISTRY (2015)

Article Multidisciplinary Sciences

Coordinated Feeding Behavior in Trichoplax, an Animal without Synapses

Carolyn L. Smith et al.

PLOS ONE (2015)

Article Multidisciplinary Sciences

Glycine activated ion channel subunits encoded by ctenophore glutamate receptor genes

Robert Alberstein et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Error, signal, and the placement of Ctenophora sister to all other animals

Nathan V. Whelan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

Amit Zeisel et al.

SCIENCE (2015)

Article Multidisciplinary Sciences

Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels

Timothy Lynagh et al.

SCIENTIFIC REPORTS (2015)

Review Biotechnology & Applied Microbiology

Umami the Fifth Basic Taste: History of Studies on Receptor Mechanisms and Role as a Food Flavor

Kenzo Kurihara

BIOMED RESEARCH INTERNATIONAL (2015)

Review Physiology

Mechanosensory molecules and circuits in C-elegans

William R. Schafer

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)

Article Biochemistry & Molecular Biology

Novel Cell Types, Neurosecretory Cells, and Body Plan of the Early-Diverging Metazoan Trichoplax adhaerens

Carolyn L. Smith et al.

CURRENT BIOLOGY (2014)

Review Plant Sciences

Glutamate signalling in roots

Brian G. Forde

JOURNAL OF EXPERIMENTAL BOTANY (2014)

Article Multidisciplinary Sciences

The ctenophore genome and the evolutionary origins of neural systems

Leonid L. Moroz et al.

NATURE (2014)

Editorial Material Multidisciplinary Sciences

Oxygen and animals in Earth history

Andrew H. Knoll et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Behavioral Sciences

Nociception and pain: lessons from optogenetics

Fiona B. Carr et al.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2014)

Article Biochemistry & Molecular Biology

Multicellularity arose several times in the evolution of eukaryotes (Response to DOI 10.1002/bies.201100187)

Laura Wegener Parfrey et al.

BIOESSAYS (2013)

Review Biotechnology & Applied Microbiology

Role of glutamate metabolism in bacterial responses towards acid and other stresses

C. Feehily et al.

JOURNAL OF APPLIED MICROBIOLOGY (2013)

Article Neurosciences

A Eukaryotic Specific Transmembrane Segment is Required for Tetramerization in AMPA Receptors

Catherine L. Salussolia et al.

JOURNAL OF NEUROSCIENCE (2013)

Review Biochemistry & Molecular Biology

SLC17: A functionally diverse family of organic anion transporters

Richard J. Reimer

MOLECULAR ASPECTS OF MEDICINE (2013)

Article Multidisciplinary Sciences

A strategy to capture and characterize the synaptic transcriptome

Sathyanarayanan V. Puthanveettil et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Endocrinology & Metabolism

Glutamate Pays Its Own Way in Astrocytes

Mary C. McKenna

Frontiers in Endocrinology (2013)

Article Neurosciences

A neurochemical map of the developing amphioxus nervous system

Simona Candiani et al.

BMC NEUROSCIENCE (2012)

Article Developmental Biology

Coordinated modulation of cellular signaling through ligand-gated ion channels in Hydra vulgaris (Cnidaria, Hydrozoa)

Paola Pierobon

INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2012)

Review Biochemistry & Molecular Biology

Structure and Pharmacology of Pentameric Receptor Channels: From Bacteria to Brain

Pierre-Jean Corringer et al.

STRUCTURE (2012)

Article Biochemical Research Methods

The Emergence and Early Evolution of Biological Carbon-Fixation

Rogier Braakman et al.

PLOS COMPUTATIONAL BIOLOGY (2012)

Review Plant Sciences

Glutamate receptor homologs in plants: functions and evolutionary origins

Michelle Beth Price et al.

FRONTIERS IN PLANT SCIENCE (2012)

Review Astronomy & Astrophysics

The Multiple Origins of Complex Multicellularity

Andrew H. Knoll

ANNUAL REVIEW OF EARTH AND PLANETARY SCIENCES, VOL 39 (2011)

Article Astronomy & Astrophysics

Photochemical Synthesis of Citric Acid Cycle Intermediates Based on Titanium Dioxide

Raffaele Saladino et al.

ASTROBIOLOGY (2011)

Article Multidisciplinary Sciences

Acoelomorph flatworms are deuterostomes related to Xenoturbella

Herve Philippe et al.

NATURE (2011)

Article Multidisciplinary Sciences

Phylogenomics reveals deep molluscan relationships

Kevin M. Kocot et al.

NATURE (2011)

Review Biochemistry & Molecular Biology

Emerging Models of Glutamate Receptor Ion Channel Structure and Function

Mark L. Mayer

STRUCTURE (2011)

Article Biochemistry & Molecular Biology

Binding of glutamate to the umami receptor

J. J. Lopez Cascales et al.

BIOPHYSICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Nematocyst discharge in Hydra vulgaris: Differential responses of desmonemes and stenoteles to mechanical and chemical stimulation

A. A. Scappaticci et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2010)

Article Biochemistry & Molecular Biology

Tubulin Polyglutamylation Regulates Axonemal Motility by Modulating Activities of Inner-Arm Dyneins

Tomohiro Kubo et al.

CURRENT BIOLOGY (2010)

Article Biochemistry & Molecular Biology

The Glutamate Effect on DNA Binding by Pol I DNA Polymerases: Osmotic Stress and the Effective Reversal of Salt Linkage

Daniel J. Deredge et al.

JOURNAL OF MOLECULAR BIOLOGY (2010)

Article Multidisciplinary Sciences

The energetics of genome complexity

Nick Lane et al.

NATURE (2010)

Article Geochemistry & Geophysics

The effects of parent body processes on amino acids in carbonaceous chondrites

Daniel P. Glavin et al.

METEORITICS & PLANETARY SCIENCE (2010)

Article Biochemistry & Molecular Biology

Protein destabilization by electrostatic repulsions in the two-stranded α-helical coiled-coil/leucine zipper

Wayne D. Kohn et al.

PROTEIN SCIENCE (2010)

Review Behavioral Sciences

Molluscan Memory of Injury: Evolutionary Insights into Chronic Pain and Neurological Disorders

Edgar T. Walters et al.

BRAIN BEHAVIOR AND EVOLUTION (2009)

Review Behavioral Sciences

On the Independent Origins of Complex Brains and Neurons

Leonid L. Moroz

BRAIN BEHAVIOR AND EVOLUTION (2009)

Article Biochemistry & Molecular Biology

Aplysia cys-loop Glutamate-Gated Chloride Channels Reveal Convergent Evolution of Ligand Specificity

JacSue Kehoe et al.

JOURNAL OF MOLECULAR EVOLUTION (2009)

Article Biochemistry & Molecular Biology

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

Bryson D. Bennett et al.

NATURE CHEMICAL BIOLOGY (2009)

Article Biochemistry & Molecular Biology

The N-terminal domain of GluR6-subtype glutamate receptor ion channels

Janesh Kumar et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

NMDA and GABAB receptors are involved in controlling nernatocyst discharge in hydra

A. A. Scappaticci et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2008)

Letter Biochemistry & Molecular Biology

Horizontal gene transfer and the evolution of cnidarian stinging cells

Elsa Denker et al.

CURRENT BIOLOGY (2008)

Review Biochemistry & Molecular Biology

Intracellular organic osmolytes: Function and regulation

Maurice B. Burg et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Multidisciplinary Sciences

The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

Nicole King et al.

NATURE (2008)

Article Multidisciplinary Sciences

Identification of a vesicular aspartate transporter

Takaaki Miyaji et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Molecular mechanism for the umami taste synergism

Feng Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

Ralph J. DeBerardinis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

A targeted multienzyme mechanism for selective microtubule polyglutamylation

Juliette van Dijk et al.

MOLECULAR CELL (2007)

Article Multidisciplinary Sciences

Loss of α-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function

Koji Ikegami et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Plant Sciences

Glutamate in plants: metabolism, regulation, and signalling

Brian G. Forde et al.

JOURNAL OF EXPERIMENTAL BOTANY (2007)

Review Biochemistry & Molecular Biology

Cnidarian chemical neurotransmission, an updated overview

G. Kass-Simon et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2007)

Article Behavioral Sciences

GABA and glutamate specifically induce contractions in the sponge Tethya wilhelma

Kornelia Ellwanger et al.

JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY (2007)

Article Biochemistry & Molecular Biology

On a hypothetical generational relationship between HCN and constituents of the reductive citric acid cycle

Albert Eschenmoser

CHEMISTRY & BIODIVERSITY (2007)

Article Pharmacology & Pharmacy

The glutamate story

JC Watkins et al.

BRITISH JOURNAL OF PHARMACOLOGY (2006)

Article Biochemistry & Molecular Biology

Neuronal transcriptome of Aplysia:: neuronal compartments and circuitry

Leonid L. Moroz et al.

Article Chemistry, Multidisciplinary

Driving parts of Krebs cycle in reverse through mineral photochemistry

Xiang V. Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2006)

Article Multidisciplinary Sciences

Deuterostome phylogeny reveals monophyletic chordates and the new phylum Xenoturbellida

Sarah J. Bourlat et al.

NATURE (2006)

Article Neurosciences

L-Glutamate and its ionotropic receptors in the nervous system of cephalopods

A. Di Cosmo et al.

CURRENT NEUROPHARMACOLOGY (2006)

Article Multidisciplinary Sciences

Amplification of enantiomeric concentrations under credible prebiotic conditions

Ronald Breslow et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Evolution of glutamine synthetase in heterokonts: Evidence for endosymbiotic gene transfer and the early evolution of photosynthesis

DL Robertson et al.

MOLECULAR BIOLOGY AND EVOLUTION (2006)

Article Endocrinology & Metabolism

Anaplerotic molecules: Current and future

Henri Brunengraber et al.

JOURNAL OF INHERITED METABOLIC DISEASE (2006)

Review Multidisciplinary Sciences

Glutamate receptors at atomic resolution

ML Mayer

NATURE (2006)

Review Biochemistry & Molecular Biology

Poly-gamma-glutamate in bacteria

Thomas Candela et al.

MOLECULAR MICROBIOLOGY (2006)

Review Pharmacology & Pharmacy

Overview of molecular relationships in the voltage-gated ion channel superfamily

FH Yu et al.

PHARMACOLOGICAL REVIEWS (2005)

Article Biochemical Research Methods

Single cell glutamate analysis in Aplysia sensory neurons

TJ Drake et al.

JOURNAL OF NEUROSCIENCE METHODS (2005)

Article Multidisciplinary Sciences

Borate minerals stabilize ribose

A Ricardo et al.

SCIENCE (2004)

Article Neurosciences

N-methyl-D-aspartate receptor-like immunoreactivity in the brain of Sepia and Octopus

A Di Cosmo et al.

JOURNAL OF COMPARATIVE NEUROLOGY (2004)

Article Multidisciplinary Sciences

Universality in intermediary metabolism

E Smith et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Neurosciences

Learning insights transmitted by glutamate

EG Antzoulatos et al.

TRENDS IN NEUROSCIENCES (2004)

Article Neurosciences

Putative NMDA receptors in Hydra:: a biochemical and functional study

P Pierobon et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2004)

Review Biotechnology & Applied Microbiology

A comprehensive evolutionary classification of proteins encoded in complete eukaryotic genomes

EV Koonin et al.

GENOME BIOLOGY (2004)

Article Biochemistry & Molecular Biology

GABA and glutamate receptors are involved in modulating pacemaker activity in hydra

G Kass-Simon et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2003)

Article Biochemistry & Molecular Biology

The cost of cortical computation

P Lennie

CURRENT BIOLOGY (2003)

Article Behavioral Sciences

New seasonings

K Ikeda

CHEMICAL SENSES (2002)

Letter Behavioral Sciences

What's in a name? Are MSG and umami the same?

BP Halpern

CHEMICAL SENSES (2002)

Article Neurosciences

The discovery of chemical neurotransmitters

ES Valenstein

BRAIN AND COGNITION (2002)

Article Multidisciplinary Sciences

Mechanism of glutamate receptor desensitization

Y Sun et al.

NATURE (2002)

Article Multidisciplinary Sciences

An amino-acid taste receptor

G Nelson et al.

NATURE (2002)

Review Multidisciplinary Sciences

Neuroscience - The neurobiology of slow synaptic transmission

P Greengard

SCIENCE (2001)

Review Endocrinology & Metabolism

An energy budget for signaling in the grey matter of the brain

D Attwell et al.

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2001)

Article Nutrition & Dietetics

Glutamine: The emperor or his clothes?

VR Young et al.

JOURNAL OF NUTRITION (2001)

Article Multidisciplinary Sciences

Cooperation and competition in the evolution of ATP-producing pathways

T Pfeiffer et al.

SCIENCE (2001)

Article Multidisciplinary Sciences

Self-organizing biochemical cycles

LE Orgel

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Multidisciplinary Sciences

The origin of intermediary metabolism

HJ Morowitz et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Biochemistry & Molecular Biology

Polyglutamylation of nucleosome assembly proteins

C Regnard et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2000)

Article Nutrition & Dietetics

Glutamate: An amino acid of particular distinction

VR Young et al.

JOURNAL OF NUTRITION (2000)

Article Neurosciences

A metabotropic glutamate receptor variant functions as a taste receptor

N Chaudhari et al.

NATURE NEUROSCIENCE (2000)