4.7 Review

HIV-1 and human genetic variation

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

The influence of human genetic variation on Epstein-Barr virus sequence diversity

Sina Rueeger et al.

Summary: This study identified significant associations between human genetic variation and EBV sequence variation, which could help dissect pathogenic mechanisms and suggest new therapeutic avenues.

SCIENTIFIC REPORTS (2021)

Article Immunology

Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores

Lena G. Dietrich et al.

Summary: Our study in Swiss people living with HIV found that an individual polygenic risk score is associated with rapid progression of kidney dysfunction, when analyzed in the context of clinical and antiretroviral risk factors.

JOURNAL OF INFECTIOUS DISEASES (2021)

Review Genetics & Heredity

Exploring the interactions between the human and viral genomes

Jacques Fellay et al.

HUMAN GENETICS (2020)

Review Multidisciplinary Sciences

A brief history of human disease genetics

Melina Claussnitzer et al.

NATURE (2020)

Article Multidisciplinary Sciences

The behavioral, cellular and immune mediators of HIV-1 acquisition: New insights from population genetics

Timothy R. Powell et al.

SCIENTIFIC REPORTS (2020)

Review Medicine, Research & Experimental

The multifaceted nature of HIV latency

Caroline Dufour et al.

JOURNAL OF CLINICAL INVESTIGATION (2020)

Article Multidisciplinary Sciences

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang et al.

SCIENCE (2020)

Article Medicine, General & Internal

Genetic architecture of cardiometabolic risks in people living with HIV

Haoxiang Chang et al.

BMC MEDICINE (2020)

Review Genetics & Heredity

Benefits and limitations of genome-wide association studies

Vivian Tam et al.

NATURE REVIEWS GENETICS (2019)

Article Multidisciplinary Sciences

VACCINOLOGY Structural topology defines protective CD8+ T cell epitopes in the HIV proteome

Gaurav D. Gaiha et al.

SCIENCE (2019)

Article Biochemistry & Molecular Biology

Gene-edited babies: What went wrong and what could go wrong

Haoyi Wang et al.

PLOS BIOLOGY (2019)

Review Biochemistry & Molecular Biology

Molecular Mechanism of HIV-1 Entry

Bing Chen

TRENDS IN MICROBIOLOGY (2019)

Article Multidisciplinary Sciences

Mapping the drivers of within-host pathogen evolution using massive data sets

Duncan S. Palmer et al.

NATURE COMMUNICATIONS (2019)

Article Biotechnology & Applied Microbiology

Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype

Daehwan Kim et al.

NATURE BIOTECHNOLOGY (2019)

Editorial Material Medicine, General & Internal

HIV Viral Load and Transmissibility of HIV Infection Undetectable Equals Untransmittable

Robert W. Eisinger et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)

Article Multidisciplinary Sciences

HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control

Jatin Arora et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Genetics & Heredity

Genotype Imputation from Large Reference Panels

Sayantan Das et al.

ANNUAL REVIEW OF GENOMICS AND HUMAN GENETICS, VOL 19 (2018)

Article Multidisciplinary Sciences

Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells

Veron Ramsuran et al.

SCIENCE (2018)

Review Genetics & Heredity

Population structure in genetic studies: Confounding factors and mixed models

Jae Hoon Sul et al.

PLOS GENETICS (2018)

Article Genetics & Heredity

HLA-HD: An accurate HLA typing algorithm for next-generation sequencing data

Shuji Kawaguchi et al.

HUMAN MUTATION (2017)

Review Genetics & Heredity

Host genetic variation and HIV disease: from mapping to mechanism

Vivek Naranbhai et al.

IMMUNOGENETICS (2017)

Review Genetics & Heredity

What has GWAS done for HLA and disease associations?

A. E. Kennedy et al.

INTERNATIONAL JOURNAL OF IMMUNOGENETICS (2017)

Article Immunology

Evaluating the Impact of Functional Genetic Variation on HIV-1 Control

Paul J. McLaren et al.

JOURNAL OF INFECTIOUS DISEASES (2017)

Editorial Material Multidisciplinary Sciences

Genomics is failing on diversity

Alice B. Popejoy et al.

NATURE (2016)

Article Genetics & Heredity

Imputation of KIR Types from SNP Variation Data

Damjan Vukcevic et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2015)

Article Biochemistry & Molecular Biology

Epigenetic regulation of differential HLA-A allelic expression levels

Veron Ramsuran et al.

HUMAN MOLECULAR GENETICS (2015)

Article Multidisciplinary Sciences

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

Paul J. McLaren et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Review Biochemistry & Molecular Biology

HIV-1 adaptation to HLA: a window into virus-host immune interactions

Jonathan M. Carlson et al.

TRENDS IN MICROBIOLOGY (2015)

Article Medicine, General & Internal

Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV

Pablo Tebas et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Multidisciplinary Sciences

RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection

Wenhui Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Immunology

Immunogenetics of HIV disease

Maureen P. Martin et al.

IMMUNOLOGICAL REVIEWS (2013)

Article Multidisciplinary Sciences

Imputing Amino Acid Polymorphisms in Human Leukocyte Antigens

Xiaoming Jia et al.

PLOS ONE (2013)

Article Biotechnology & Applied Microbiology

Pharmacogenetics-based population pharmacokinetic analysis of etravirine in HIV-1 infected individuals

Rubin Lubomirov et al.

PHARMACOGENETICS AND GENOMICS (2013)

Article Multidisciplinary Sciences

Influence of HLA-C Expression Level on HIV Control

Richard Apps et al.

SCIENCE (2013)

Article Biochemistry & Molecular Biology

Interrogating the major histocompatibility complex with high-throughput genomics

Paul I. W. de Bakker et al.

HUMAN MOLECULAR GENETICS (2012)

Article Biochemistry & Molecular Biology

Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans

Paul J. McLaren et al.

HUMAN MOLECULAR GENETICS (2012)

Article Multidisciplinary Sciences

HIV-1 adaptation to NK-cell-mediated immune pressure

Galit Alter et al.

NATURE (2011)

Article Multidisciplinary Sciences

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

Thomas Pertel et al.

NATURE (2011)

Article Multidisciplinary Sciences

Differential microRNA regulation of HLA-C expression and its association with HIV control

Smita Kulkarni et al.

NATURE (2011)

Article Immunology

Cohorts for the Study of HIV-1-Exposed but Uninfected Individuals: Benefits and Limitations

R. E. Horton et al.

JOURNAL OF INFECTIOUS DISEASES (2010)

Article Immunology

Host Determinants of HIV-1 Control in African Americans

Kimberly Pelak et al.

JOURNAL OF INFECTIOUS DISEASES (2010)

Article Biotechnology & Applied Microbiology

ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir

Rubin Lubomirov et al.

PHARMACOGENETICS AND GENOMICS (2010)

Article Multidisciplinary Sciences

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

Florencia Pereyra et al.

SCIENCE (2010)

Article Pharmacology & Pharmacy

Pharmacogenetics-Based Population Pharmacokinetic Analysis of Efavirenz in HIV-1-Infected Individuals

M. Arab-Alameddine et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2009)

Review Genetics & Heredity

The HLA genomic loci map: expression, interaction, diversity and disease

Takashi Shiina et al.

JOURNAL OF HUMAN GENETICS (2009)

Article Multidisciplinary Sciences

Direct activation of protein kinases by unanchored polyubiquitin chains

Zong-Ping Xia et al.

NATURE (2009)

Article Multidisciplinary Sciences

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

Dongliang Ge et al.

NATURE (2009)

Article Multidisciplinary Sciences

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

David L. Thomas et al.

NATURE (2009)

Article Medicine, General & Internal

Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantaion

Gero Huetter et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Biotechnology & Applied Microbiology

In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function

Julia di Iulio et al.

PHARMACOGENETICS AND GENOMICS (2009)

Article Genetics & Heredity

Common Genetic Variation and the Control of HIV-1 in Humans

Jacques Fellay et al.

PLOS GENETICS (2009)

Article Multidisciplinary Sciences

A whole-genome association study of major determinants for host control of HIV-1

Jacques Fellay et al.

SCIENCE (2007)

Article Multidisciplinary Sciences

HIV-1 proviral DNA excision using an evolved recombinase

Indrani Sarkar et al.

SCIENCE (2007)

Article Pharmacology & Pharmacy

Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals

M. Rotger et al.

CLINICAL PHARMACOLOGY & THERAPEUTICS (2007)

Article Biochemistry & Molecular Biology

The geographic spread of the CCR5 Δ32 HIV-resistance allele

J Novembre et al.

PLOS BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1

G Fätkenheuer et al.

NATURE MEDICINE (2005)

Article Multidisciplinary Sciences

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA

P Kiepiela et al.

NATURE (2004)

Review Genetics & Heredity

Gene map of the extended human MHC

R Horton et al.

NATURE REVIEWS GENETICS (2004)

Article Immunology

Coronary heart disease in HIV-infected individuals

JS Currier et al.

JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2003)

Review Biochemistry & Molecular Biology

Immunopathogenesis and immunotherapy in AIDS virus infections

NL Letvin et al.

NATURE MEDICINE (2003)

Article Genetics & Heredity

Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS

MP Martin et al.

NATURE GENETICS (2002)

Article Medicine, General & Internal

Genetic variations in HLA-B region and hypersensitivity reactions to abacavir

S Hetherington et al.

LANCET (2002)

Article Medicine, General & Internal

Effect of a single amino acid change in MHC class I molecules on the rate of progression to AIDS.

XJ Gao et al.

NEW ENGLAND JOURNAL OF MEDICINE (2001)

Article Multidisciplinary Sciences

HLA B*5701 is highly associated with restriction of virus replication in a subgroup of HIV-infected long term nonprogressors

SA Migueles et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)

Article Medicine, General & Internal

Viral load and heterosexual transmission of human immunodeficiency virus type 1

TC Quinn et al.

NEW ENGLAND JOURNAL OF MEDICINE (2000)