4.8 Editorial Material

Molecular omics resources should require sex annotation: a call for action

Journal

NATURE METHODS
Volume 18, Issue 6, Pages 585-588

Publisher

NATURE RESEARCH
DOI: 10.1038/s41592-021-01168-6

Keywords

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Funding

  1. NIH [R01NS060752, R01CA164371, U54CA143970, U54CA193489, U01CA220378, U54CA210180, U01CA250481, R01DA039062, R01MH091424]
  2. James S. McDonnell Foundation
  3. Ben & Catherine Ivy Foundation
  4. Zicarelli Foundation
  5. Arizona Biomedical Research Commission
  6. Mayo Clinic
  7. NCI [R01CA174737, P01CA245705]

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The commonly used omics databases primarily include male samples, limiting the understanding of the biology of sex differences.
The most commonly used omics databases are a compilation of results from primarily male-only and sex-agnostic studies. The pervasive use of these databases critically hinders progress toward fully accounting for the biology of sex differences.

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