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SARS-CoV-2 targets MAVS for immune evasion

Journal

NATURE CELL BIOLOGY
Volume 23, Issue 7, Pages 682-683

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41556-021-00712-y

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A new study has shown that the SARS-CoV-2 nucleocapsid protein can suppress the antiviral response by directly interacting with the signalling adaptor protein MAVS. Targeting this pathway could be a promising therapeutic strategy to enhance immunity against COVID-19.
A new study shows that the SARS-CoV-2 nucleocapsid protein represses the antiviral type I interferon response through direct interaction with the signalling adaptor protein MAVS. Targeting this process might be a useful therapeutic strategy to boost immunity against COVID-19.

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