4.8 Article

Spontaneous formation of β-sheet nano-barrels during the early aggregation of Alzheimer's amyloid beta

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Sclerotiorin Stabilizes the Assembly of Nonfibrillar Abeta42 Oligomers with Low Toxicity, Seeding Activity, and Beta-sheet Content

Thomas Wiglenda et al.

JOURNAL OF MOLECULAR BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide

Yunxiang Sun et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)

Article Multidisciplinary Sciences

Structure of amyloid β25-35 in lipid environment and cholesterol-dependent membrane pore formation

Nabin Kandel et al.

SCIENTIFIC REPORTS (2019)

Article Chemistry, Multidisciplinary

Native Ion Mobility-Mass Spectrometry Reveals the Formation of β-Barrel Shaped Amyloid-β Hexamers in a Membrane-Mimicking Environment

Nicklas Osterlund et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Multidisciplinary Sciences

Molecular structure of an N-terminal phosphorylated β-amyloid fibril

Zhi-Wen Hu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Chemistry, Physical

Tetrameric Aβ40 and Aβ42 β-Barrel Structures by Extensive Atomistic Simulations. II. In Aqueous Solution

Phuong H. Nguyen et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2019)

Article Biochemistry & Molecular Biology

Distinct Primary Nucleation of Polymorphic Aβ Dimers Yields to Distinguished Fibrillation Pathways

Olga Press-Sandler et al.

ACS CHEMICAL NEUROSCIENCE (2019)

Review Biochemistry & Molecular Biology

Key Peptides and Proteins in Alzheimer's Disease

Botond Penke et al.

CURRENT PROTEIN & PEPTIDE SCIENCE (2019)

Article Biochemistry & Molecular Biology

In silico investigation on the inhibition of A(42) aggregation by A(40) peptide by potential of mean force study

Mary Dutta et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2018)

Article Biochemistry & Molecular Biology

Structures and dynamics of beta-barrel oligomer intermediates of amyloid-beta16-22 aggregation

Xinwei Ge et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2018)

Article Chemistry, Multidisciplinary

Aggregation kinetics of the Aβ1-40 peptide monitored by NMR

Giovanni Bellomo et al.

CHEMICAL COMMUNICATIONS (2018)

Review Chemistry, Multidisciplinary

Secondary nucleation in amyloid formation

Mattias Tornquist et al.

CHEMICAL COMMUNICATIONS (2018)

Article Multidisciplinary Sciences

On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations

Xiaoting Yang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Neurosciences

Amyloid toxicity in Alzheimer's disease

Allison B. Reiss et al.

REVIEWS IN THE NEUROSCIENCES (2018)

Article Education, Scientific Disciplines

Question order and student understanding of structure and function

Kelli P. Carter et al.

ADVANCES IN PHYSIOLOGY EDUCATION (2018)

Review Cell Biology

A new era for understanding amyloid structures and disease

Matthew G. Iadanza et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)

Article Multidisciplinary Sciences

β-barrel Oligomers as Common Intermediates of Peptides Self-Assembling into Cross-β Aggregates

Yunxiang Sun et al.

SCIENTIFIC REPORTS (2018)

Article Chemistry, Multidisciplinary

Mitigating Human IAPP Amyloidogenesis In Vivo with Chiral Silica Nanoribbons

Ava Faridi et al.

SMALL (2018)

Article Chemistry, Physical

Discrete Molecular Dynamics Approack to the Study of Disordered and Aggregating Proteins

Agusti Emperador et al.

JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2017)

Article Chemistry, Physical

Membrane Binding and Pore Formation by a Cytotoxic Fragment of Amyloid β Peptide

Nabin Kandel et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2017)

Article Chemistry, Multidisciplinary

A Free Energy Barrier Caused by the Refolding of an Oligomeric Intermediate Controls the Lag Time of Amyloid Formation by hIAPP

Arnaldo L. Serrano et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Article Multidisciplinary Sciences

Fibril structure of amyloid-β(1-42) by cryo-electron microscopy

Lothar Gremer et al.

SCIENCE (2017)

Article Multidisciplinary Sciences

Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution

Martin Wolff et al.

SCIENTIFIC REPORTS (2017)

Article Biochemistry & Molecular Biology

Cofibrillization of Pathogenic and Functional Amyloid Proteins with Gold Nanoparticles against Amyloidogenesis

Ibrahim Javed et al.

BIOMACROMOLECULES (2017)

Review Chemistry, Multidisciplinary

Implications of peptide assemblies in amyloid diseases

Pu Chun Ke et al.

CHEMICAL SOCIETY REVIEWS (2017)

Article Biochemistry & Molecular Biology

Impact of Cu(II) Binding on Structures and Dynamics of Aβ42 Monomer and Dimer: Molecular Dynamics Study

Pham Dinh Quoc Huy et al.

ACS CHEMICAL NEUROSCIENCE (2016)

Article Biochemistry & Molecular Biology

Applications of Discrete Molecular Dynamics in biology and medicine

Elizabeth A. Proctor et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2016)

Article Chemistry, Multidisciplinary

Amyloid β-Protein C-Terminal Fragments: Formation of Cylindrins and β-Barrels

Thanh D. Do et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Chemistry, Multidisciplinary

Atomic Resolution Structure of Monomorphic Aβ42 Amyloid Fibrils

Michael T. Colvin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Article Multidisciplinary Sciences

Aβ42 assembles into specific β-barrel pore-forming oligomers in membrane-mimicking environments

Montserrat Serra-Batiste et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Atomic-resolution structure of a disease-relevant Aβ(1-42) amyloid fibril

Marielle Aulikki Walti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Biochemistry & Molecular Biology

A2T and A2V A peptides exhibit different aggregation kinetics, primary nucleation, morphology, structure, and LTP inhibition

Brian Murray et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2016)

Article Multidisciplinary Sciences

Common molecular mechanism of amyloid pore formation by Alzheimer's β-amyloid peptide and α-synuclein

Coralie Di Scala et al.

SCIENTIFIC REPORTS (2016)

Review Chemistry, Multidisciplinary

Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies

Jessica Nasica-Labouze et al.

CHEMICAL REVIEWS (2015)

Article Biochemistry & Molecular Biology

Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

Yiling Xiao et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Aβ(1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

Yiling Xiao et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)

Article Chemistry, Multidisciplinary

Atomic-Resolution Three-Dimensional Structure of Amyloid β Fibrils Bearing the Osaka Mutation

Anne K. Schuetz et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Biochemistry & Molecular Biology

The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation

Iryna Benilova et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2014)

Article Biochemistry & Molecular Biology

Molecular Structure of β-Amyloid Fibrils in Alzheimer's Disease Brain Tissue

Jun-Xia Lu et al.

Article Biochemistry & Molecular Biology

Aβ Monomers Transiently Sample Oligomer and Fibril-Like Configurations: Ensemble Characterization Using a Combined MD/NMR Approach

David J. Rosenman et al.

JOURNAL OF MOLECULAR BIOLOGY (2013)

Review Multidisciplinary Sciences

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

Mathias Jucker et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

The stability of cylindrin -barrel amyloid oligomer modelsA molecular dynamics study

Workalemahu M. Berhanu et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2013)

Review Chemistry, Multidisciplinary

Membrane Disruption and Early Events in the Aggregation of the Diabetes Related Peptide IAPP from a Molecular Perspective

Jeffrey R. Brender et al.

ACCOUNTS OF CHEMICAL RESEARCH (2012)

Article Biochemistry & Molecular Biology

Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils

Jan Bieschke et al.

NATURE CHEMICAL BIOLOGY (2012)

Review Neurosciences

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

Iryna Benilova et al.

NATURE NEUROSCIENCE (2012)

Article Multidisciplinary Sciences

Atomic View of a Toxic Amyloid Small Oligomer

Arthur Laganowsky et al.

SCIENCE (2012)

Article Chemistry, Physical

Effects of surface interactions on peptide aggregate morphology

Alex Morriss-Andrews et al.

JOURNAL OF CHEMICAL PHYSICS (2011)

Article Biochemistry & Molecular Biology

Amyloid-β forms fibrils by nucleated conformational conversion of oligomers

Jiyong Lee et al.

NATURE CHEMICAL BIOLOGY (2011)

Article Chemistry, Multidisciplinary

Identification of Hot Regions of the A beta-IAPP Interaction Interface as High-Affinity Binding Sites in both Cross- and Self-Association

Erika Andreetto et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Biochemistry & Molecular Biology

Effects of the English (H6R) and Tottori (D7N) Familial Alzheimer Disease Mutations on Amyloid β-Protein Assembly and Toxicity

Kenjiro Ono et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Beta-barrel models of soluble amyloid beta oligomers and annular protofibrils

Yinon Shafrir et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2010)

Article Chemistry, Multidisciplinary

Human Islet Amyloid Polypeptide Monomers Form Ordered β-hairpins: A Possible Direct Amyloidogenic Precursor

Nicholas F. Dupuis et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Article Multidisciplinary Sciences

Structure-neurotoxicity relationships of amyloid β-protein oligomers

Kenjiro Ono et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Probing protein aggregation using discrete molecular dynamics

Shantanu Sharma et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2008)

Article Multidisciplinary Sciences

Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation

Wolfgang Hoyer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Molecular structural basis for polymorphism in Alzheimer's β-amyloid fibrils

Anant K. Paravastu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

The Alzheimer's peptides Aβ40 and 42 adopt distinct conformations in water:: A combined MD/NMR study

Nikolaos G. Sgourakis et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Mechanism for the α-helix to β-hairpin transition

F Ding et al.

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2003)

Article Multidisciplinary Sciences

Amyloid β-protein (Aβ) assembly:: Aβ40 and Aβ42 oligomerize through distinct pathways

G Bitan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Review Biochemistry & Molecular Biology

Identification and characterization of key kinetic intermediates in amyloid β-protein fibrillogenesis

MD Kirkitadze et al.

JOURNAL OF MOLECULAR BIOLOGY (2001)