4.6 Review

Evolution and function of the epithelial cell-specific ER stress sensor IRE1β

Related references

Note: Only part of the references are listed.
Review Cell Biology

Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity

Eelco van Anken et al.

Summary: This article discusses how the UPR responds to ER stress, how it is repurposed in B cells, and how UPR-driven counter-selection of cells undergoing homeostatic failure serves organismal homeostasis and humoral immunity.

TRENDS IN CELL BIOLOGY (2021)

Article Multidisciplinary Sciences

An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function

Elisabeth E. L. Nystrom et al.

Summary: Intestinal goblet cells are not homogeneous, with several distinct subtypes forming two differentiation trajectories. Intercrypt goblet cells located at the colonic luminal surface produce mucus with different properties from crypt-residing goblet cells. Defective icGCs in mice lead to increased sensitivity to chemically induced colitis and spontaneous colitis with age, while alterations in mucus and reduced numbers of icGCs are observed in patients with ulcerative colitis, highlighting the importance of icGCs in maintaining functional epithelial protection.

SCIENCE (2021)

Article Cell Biology

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress

Michael J. Grey et al.

JOURNAL OF CELL BIOLOGY (2020)

Article Multidisciplinary Sciences

Quantitative microscopy reveals dynamics and fate of clustered IRE1α

Vladislav Belyy et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Cell Biology

Mechanisms, regulation and functions of the unfolded protein response

Claudio Hetz et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

Christopher S. Smillie et al.

Article Biochemistry & Molecular Biology

A cellular census of human lungs identifies novel cell states in health and in asthma

Felipe A. Vieira Braga et al.

NATURE MEDICINE (2019)

Article Medicine, Research & Experimental

IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis

Gang Chen et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Article Biochemistry & Molecular Biology

Development of a Chemical Toolset for Studying the Paralog-Specific Function of IRE1

Hannah C. Feldman et al.

ACS CHEMICAL BIOLOGY (2019)

Article Cell Biology

Early Events in the Endoplasmic Reticulum Unfolded Protein Response

Steffen Preissler et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2019)

Review Immunology

ER Stress and the UPR in Shaping Intestinal Tissue Homeostasis and Immunity

Olivia Coleman et al.

FRONTIERS IN IMMUNOLOGY (2019)

Review Biochemistry & Molecular Biology

Structure and Molecular Mechanism of ER Stress Signaling by the Unfolded Protein Response Signal Activator IRE1

Christopher J. Adams et al.

FRONTIERS IN MOLECULAR BIOSCIENCES (2019)

Article Gastroenterology & Hepatology

The Food Additive Maltodextrion promotes Endoplasmic Reticulum Stress-Driven Mucus Depletion and Exacerbates Intestinal Inflammation

Federica Laudisi et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2019)

Article Biochemistry & Molecular Biology

UFBoot2: Improving the Ultrafast Bootstrap Approximation

Diep Thi Hoang et al.

MOLECULAR BIOLOGY AND EVOLUTION (2018)

Review Biochemistry & Molecular Biology

The Unfolded Protein Response and Cell Fate Control

Claudio Hetz et al.

MOLECULAR CELL (2018)

Article Multidisciplinary Sciences

Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota

Keisuke Nakashima et al.

NATURE COMMUNICATIONS (2018)

Article Immunology

Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis

Markus Tschurtschenthaler et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Article Biochemistry & Molecular Biology

Activation of the Unfolded Protein Response by Lipid Bilayer Stress

Kristina Halbleib et al.

MOLECULAR CELL (2017)

Review Biochemistry & Molecular Biology

The UPRER: Sensor and Coordinator of Organismal Homeostasis

Ashley E. Frakes et al.

MOLECULAR CELL (2017)

Article Multidisciplinary Sciences

A single-cell survey of the small intestinal epithelium

Adam L. Haber et al.

NATURE (2017)

Article Cell Biology

Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival

Simon J. Tavernier et al.

NATURE CELL BIOLOGY (2017)

Article Biochemistry & Molecular Biology

A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response

Niko Amin-Wetzel et al.

Article Biochemistry & Molecular Biology

Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands

Hannah C. Feldman et al.

ACS CHEMICAL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

PDIA6 regulates insulin secretion by selectively inhibiting the RIDD activity of IRE1

Daniela Eletto et al.

FASEB JOURNAL (2016)

Article Multidisciplinary Sciences

High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22

Max Gulhane et al.

SCIENTIFIC REPORTS (2016)

Article Cell Biology

Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status

Kristin Moore et al.

MOLECULAR BIOLOGY OF THE CELL (2015)

Review Immunology

New developments in goblet cell mucus secretion and function

G. M. H. Birchenough et al.

MUCOSAL IMMUNOLOGY (2015)

Article Multidisciplinary Sciences

Tissue-based map of the human proteome

Mathias Uhlen et al.

SCIENCE (2015)

Article Biochemistry & Molecular Biology

IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies

Lam-Tung Nguyen et al.

MOLECULAR BIOLOGY AND EVOLUTION (2015)

Article Pharmacology & Pharmacy

Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity

Nestor O. Concha et al.

MOLECULAR PHARMACOLOGY (2015)

Article Biochemistry & Molecular Biology

Protein Disulfide Isomerase A6 Controls the Decay of IRE1α Signaling via Disulfide-Dependent Association

Davide Eletto et al.

MOLECULAR CELL (2014)

Review Biochemistry & Molecular Biology

Getting RIDD of RNA: IRE1 in cell fate regulation

M. Maurel et al.

TRENDS IN BIOCHEMICAL SCIENCES (2014)

Article Cell Biology

Ire1 Has Distinct Catalytic Mechanisms for XBP1/HAC1 Splicing and RIDD

Arvin B. Tam et al.

CELL REPORTS (2014)

Article Biochemistry & Molecular Biology

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

Kazutaka Katoh et al.

MOLECULAR BIOLOGY AND EVOLUTION (2013)

Article Cell Biology

Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells

Deepika Gaddam et al.

MOLECULAR BIOLOGY OF THE CELL (2013)

Article Multidisciplinary Sciences

Paneth cells as a site of origin for intestinal inflammation

Timon E. Adolph et al.

NATURE (2013)

Article Multidisciplinary Sciences

Regulation of Sumo mRNA during Endoplasmic Reticulum Stress

Kristin A. Moore et al.

PLOS ONE (2013)

Article Multidisciplinary Sciences

Negative feedback by IRE1β optimizes mucin production in goblet cells

Akio Tsuru et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains

Romain Volmer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Biochemistry & Molecular Biology

AGR2 Is Induced in Asthma and Promotes Allergen-Induced Mucin Overproduction

Bradley W. Schroeder et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)

Review Cell Biology

Structural Basis of the Unfolded Protein Response

Alexei Korennykh et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 28 (2012)

Article Immunology

IRE1α activation protects mice against acetaminophen-induced hepatotoxicity

Kyu Yeon Hur et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2012)

Article Multidisciplinary Sciences

Goblet cells deliver luminal antigen to CD103+ dendritic cells in the small intestine

Jeremiah R. McDole et al.

NATURE (2012)

Article Multidisciplinary Sciences

Direct Association of Unfolded Proteins with Mammalian ER Stress Sensor, IRE1β

Daisuke Oikawa et al.

PLOS ONE (2012)

Article Biochemistry & Molecular Biology

Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response

Maruf M. U. Ali et al.

EMBO JOURNAL (2011)

Review Multidisciplinary Sciences

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

Peter Walter et al.

SCIENCE (2011)

Article Biochemistry & Molecular Biology

Decrease in Membrane Phospholipid Unsaturation Induces Unfolded Protein Response

Hiroyuki Ariyama et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Identification of a consensus element recognized and cleaved by IRE1α

Daisuke Oikawa et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Multidisciplinary Sciences

Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering

Han Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Cell Biology

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

Julie Hollien et al.

JOURNAL OF CELL BIOLOGY (2009)

Article Multidisciplinary Sciences

The unfolded protein response signals through high-order assembly of Ire1

Alexei V. Korennykh et al.

NATURE (2009)

Article Cell Biology

IRE1β inhibits chylomicron production by selectively degrading MTP mRNA

Jahangir Iqbal et al.

CELL METABOLISM (2008)

Article Biochemistry & Molecular Biology

RNase domains determine the functional difference between IRE1α and IRE1β

Yusuke Imagawa et al.

FEBS LETTERS (2008)

Review Biochemical Research Methods

Comparative biology: beyond sequence analysis

Itay Tirosh et al.

CURRENT OPINION IN BIOTECHNOLOGY (2007)

Article Biochemistry & Molecular Biology

XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

Diego Acosta-Alvear et al.

MOLECULAR CELL (2007)

Article Multidisciplinary Sciences

The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response

Jiahai Zhou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response

Julie Hollien et al.

SCIENCE (2006)

Article Gastroenterology & Hepatology

Muc2-deficient mice spontaneously develop colitis, indicating that Muc2 is critical for colonic protection

Maria Van der Sluis et al.

GASTROENTEROLOGY (2006)

Article Multidisciplinary Sciences

On the mechanism of sensing unfolded protein in the endoplasmic reticulum

JJ Credle et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Two rounds of whole genome duplication in the ancestral vertebrate

P Dehal et al.

PLOS BIOLOGY (2005)

Article Biochemistry & Molecular Biology

ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures

M Landau et al.

NUCLEIC ACIDS RESEARCH (2005)

Article Multidisciplinary Sciences

Bypassing a kinase activity with an ATP-competitive drug

FR Papa et al.

SCIENCE (2003)

Article Biochemistry & Molecular Biology

XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response

AH Lee et al.

MOLECULAR AND CELLULAR BIOLOGY (2003)

Article Medicine, Research & Experimental

Increased sensitivity to dextran sodium sulfate colitis in IRE1β-deficient mice

A Bertolotti et al.

JOURNAL OF CLINICAL INVESTIGATION (2001)