Xanthone Glucosides: Isolation, Bioactivity and Synthesis

Xanthones are secondary metabolites found in plants, fungi, lichens, and bacteria from a variety of families and genera, with the majority found in the Gentianaceae, Polygalaceae, and Clusiaceae. They have a diverse range of bioactivities, including anti-oxidant, anti-bacterial, anti-malarial, anti-tuberculosis, and cytotoxic properties. Xanthone glucosides are a significant branch of xanthones. After glycosylation, xanthones may have improved characteristics (such as solubility and pharmacological activity). Currently, no critical review of xanthone glucosides has been published. A literature survey including reports of naturally occurring xanthone glucosides is included in this review. The isolation, structure, bioactivity, and synthesis of these compounds were all explored in depth.

Automated summary

Xanthones are a diverse group of secondary metabolites found in various plants, fungi, lichens, and bacteria, with a majority in families such as Gentianaceae, Polygalaceae, and Clusiaceae. Xanthone glucosides, an important branch of xanthones, have potential improved characteristics after glycosylation. This review provides a comprehensive literature survey on naturally occurring xanthone glucosides, exploring their isolation, structure, bioactivity, and synthesis.