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Gluconeogenesis in Plants: A Key Interface between Organic Acid/Amino Acid/Lipid and Sugar Metabolism

Journal

MOLECULES
Volume 26, Issue 17, Pages -

Publisher

MDPI
DOI: 10.3390/molecules26175129

Keywords

gluconeogenesis; malate; malic enzyme; nitrogen metabolism; organic acids; phosphoenolpyruvate carboxykinase; pyruvate orthophosphate dikinase; vacuole

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This article provides a concise overview of plant gluconeogenesis, highlighting its widespread occurrence and utilization in various processes. It stresses the importance of vacuolar storage and release of Krebs cycle acids/nitrogenous compounds, as well as the role of enzyme activity control in coordinating gluconeogenesis and malate metabolism.
Gluconeogenesis is a key interface between organic acid/amino acid/lipid and sugar metabolism. The aims of this article are four-fold. First, to provide a concise overview of plant gluconeogenesis. Second, to emphasise the widespread occurrence of gluconeogenesis and its utilisation in diverse processes. Third, to stress the importance of the vacuolar storage and release of Krebs cycle acids/nitrogenous compounds, and of the role of gluconeogenesis and malic enzyme in this process. Fourth, to outline the contribution of fine control of enzyme activity to the coordinate-regulation of gluconeogenesis and malate metabolism, and the importance of cytosolic pH in this.

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