Journal
MOLECULAR AND CELLULAR BIOCHEMISTRY
Volume 476, Issue 12, Pages 4265-4275Publisher
SPRINGER
DOI: 10.1007/s11010-021-04242-x
Keywords
MicroRNA; Lung; Apoptosis
Categories
Funding
- Natural Science Foundation of Hunan Province [2020JJ4527, 2019JJ50494]
- Scientific Research Fund of Hunan Provincial Education Department [20A438]
- Hunan Key Laboratory [2019TP1027]
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miRNAs play a crucial role in the development and progression of various lung diseases by regulating host cell apoptosis.
MicroRNAs (miRNAs) are a type of endogenous non-coding short-chain RNA, which plays a crucial role in the regulation of many essential cellular functions, including cellular migration, proliferation, invasion, autophagy, oxidative stress, apoptosis, and differentiation. The lung can be damaged by pathogenic microorganisms, as well as physical or chemical factors. Research has confirmed that miRNAs and lung cell apoptosis can affect the development and progression of several lung diseases. This article reviews the role of miRNAs in the development of lung disease through regulating host cell apoptosis.
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