4.5 Review

The advances of topology optimization techniques in orthopedic implants: A review

Journal

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
Volume 59, Issue 9, Pages 1673-1689

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s11517-021-02361-7

Keywords

Topology optimization; Finite element analysis; Orthopedic implants; Global layout structure; Hierarchical structure

Funding

  1. National Natural Science Foundation of China [82072456, 81802174]
  2. National Key R&D Program of China [2018YFB1105100]
  3. Department of Science and Technology of Jilin Province, P.R.C. [20200404202YY, 20200403086SF, 20200201453JC]
  4. Department of finance in Jilin province [2019SCZT046, 2020SCZT037, 201817294302]
  5. Undergraduate teaching reform research project of Jilin University [4Z2000610852]
  6. Key training plan for outstanding young teachers of Jilin University [419080520253]
  7. Bethune plan of Jilin University [470110000692]
  8. Jilin Province Development and Reform Commission, P.R.C. [2018C010]

Ask authors/readers for more resources

This article discusses the application of metal implants in the treatment of orthopedic diseases and the topology optimization technique. By optimizing the design with TO technology, stress shielding issues can be more effectively addressed. The article summarizes the characteristics of implants, TO methods, validation methods, and research limitations, and proposes future challenges and research directions.
Metal implants are widely used in the treatment of orthopedic diseases. However, owing to the mismatched elastic modulus of the bone and implants, stress shielding often occurs clinically which can result in failure of the implant or fractures around the implant. Topology optimization (TO) is a technique that can provide more efficient material distribution according to the objective function under the special load and boundary conditions. Several researchers have paid close attention to TO for optimal design of orthopedic implants. Thanks to the development of additive manufacturing (AM), the complex structure of the TO design can be fabricated. This article mainly focuses on the current stage of TO technique with respect to the global layout and hierarchical structure in orthopedic implants. In each aspect, diverse implants in different orthopedic fields related to TO design are discussed. The characteristics of implants, methods of TO, validation methods of the newly designed implants, and limitations of current research have been summarized. The review concludes with future challenges and directions for research.

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