Related references
Note: Only part of the references are listed.Anti-fibrotic effects of curcumin and some of its analogues in the heart
Armita Mahdavi Gorabi et al.
HEART FAILURE REVIEWS (2020)
Neuroprotection: Targeting Multiple Pathways by Naturally Occurring Phytochemicals
Andleeb Khan et al.
BIOMEDICINES (2020)
Blood-brain barrier-penetrating siRNA nanomedicine for Alzheimer's disease therapy
Yutong Zhou et al.
SCIENCE ADVANCES (2020)
Amelioration of Aluminum Maltolate-Induced Inflammation and Endoplasmic Reticulum Stress-Mediated Apoptosis by Tannoid Principles of Emblica officinalis in Neuronal Cellular Model
Mathiyazahan Dhivya Bharathi et al.
NEUROTOXICITY RESEARCH (2019)
Beneficial Role of Phytochemicals on Oxidative Stress and Age-Related Diseases
Cinzia Forni et al.
BIOMED RESEARCH INTERNATIONAL (2019)
STAT3: A Potential Drug Target for Tumor and Inflammation
Yang Sheng Hu et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2019)
Curcumin restores innate immune Alzheimer's disease risk gene expression to ameliorate Alzheimer pathogenesis
B. Teter et al.
NEUROBIOLOGY OF DISEASE (2019)
Olfactory Ensheathing Cells Grafted Into the Retina of RCS Rats Suppress Inflammation by Down-Regulating the JAK/STAT Pathway
Jing Xie et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2019)
Curcumin Protects Human Umbilical Vein Endothelial Cells against H2O2-Induced Cell Injury
Jipeng Ouyang et al.
PAIN RESEARCH & MANAGEMENT (2019)
Neuroinflammation as a Common Feature of Neurodegenerative Disorders
Leonardo Guzman-Martinez et al.
FRONTIERS IN PHARMACOLOGY (2019)
Curcumin reduces inflammation in knee osteoarthritis rats through blocking TLR4/MyD88/NF-κB signal pathway
Yun Zhang et al.
DRUG DEVELOPMENT RESEARCH (2019)
Protective effects of curcumin against ischemia-reperfusion injury in the liver
Kowsar Bavarsad et al.
PHARMACOLOGICAL RESEARCH (2019)
Curcumin Regulates Anti-Inflammatory Responses by JAK/STAT/SOCS Signaling Pathway in BV-2 Microglial Cells
Chiara Porro et al.
BIOLOGY-BASEL (2019)
JAK/STAT Signal Transduction: Promising Attractive Targets for Immune, Inflammatory and Hematopoietic Diseases
Qianwen Gao et al.
CURRENT DRUG TARGETS (2018)
Molecular imaging of neuroinflammation in Alzheimer's disease and mild cognitive impairment
Dunja Knezevic et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2018)
The twilight of immunity: emerging concepts in aging of the immune system
Janko Nikolich-Zugich
NATURE IMMUNOLOGY (2018)
Naringenin reduces oxidative stress and improves mitochondrial dysfunction via activation of the Nrf2/ARE signaling pathway in neurons
Kaihua Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2017)
Effect of the oral administration of nanoencapsulated quercetin on a mouse model of Alzheimer's disease
Lina Clara Gayoso e Ibiapina Moreno et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2017)
Aging increases cell-to-cell transcriptional variability upon immune stimulation
Celia Pilar Martinez-Jimenez et al.
SCIENCE (2017)
Spatial and Temporal Control of Senescence
Yoko Ito et al.
TRENDS IN CELL BIOLOGY (2017)
Inflammatory responses and inflammation-associated diseases in organs
Linlin Chen et al.
Oncotarget (2017)
被撤回的出版物: Protective effects of gingerol on streptozotocin-induced sporadic Alzheimer's disease: emphasis on inhibition of β-amyloid, COX-2, alpha-, beta - secretases and APH1a (Retracted article. See vol. 13, 2023)
Ali M. El Halawany et al.
SCIENTIFIC REPORTS (2017)
Green Tea Extracts Epigallocatechin-3-gallate for Different Treatments
Chenyu Chu et al.
BIOMED RESEARCH INTERNATIONAL (2017)
Nuclear Factor-Kappa B and Alzheimer Disease, Unifying Genetic and Environmental Risk Factors from Cell to Humans
Simon Vann Jones et al.
FRONTIERS IN IMMUNOLOGY (2017)
Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling β-amyloid production
Sandra Colie et al.
SCIENTIFIC REPORTS (2017)
Age-associated B cells (ABC) inhibit B lymphopoiesis and alter antibody repertoires in old age
Richard L. Riley et al.
CELLULAR IMMUNOLOGY (2017)
Ethanol-induced PGE2 up-regulates Aβ production through PKA/CREB signaling pathway
Amr Ahmed Gabr et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2017)
Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns
Martin Enge et al.
CELL (2017)
The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells
Farhad Seif et al.
CELL COMMUNICATION AND SIGNALING (2017)
Protective effects of gingerol on streptozotocin-induced sporadic Alzheimer's disease: emphasis on inhibition of β-amyloid, COX-2, alpha-, beta-secretases and APH1a
Ali M. El Halawany et al.
SCIENTIFIC REPORTS (2017)
Age-associated B cells: key mediators of both protective and autoreactive humoral responses
Martin S. Naradikian et al.
IMMUNOLOGICAL REVIEWS (2016)
Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain
Katarzyna Popiolek-Barczyk et al.
CURRENT MEDICINAL CHEMISTRY (2016)
Aging of the immune system: Focus on inflammation and vaccination
Marcello Pinti et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2016)
The Antioxidant Effects of Thymoquinone in Activated BV-2 Murine Microglial Cells
Makini K. Cobourne-Duval et al.
NEUROCHEMICAL RESEARCH (2016)
Functions of flavonoids in the central nervous system: Astrocytes as targets for natural compounds
Isadora Matias et al.
NEUROCHEMISTRY INTERNATIONAL (2016)
Protection against β-amyloid-induced neurotoxicity by naturally occurring Z-ligustilide through the concurrent regulation of p38 and PI3-K/Akt pathways
Wei Xu et al.
NEUROCHEMISTRY INTERNATIONAL (2016)
Dietary pattern and antioxidants in plasma and erythrocyte in patients with mild cognitive impairment from China
Linhong Yuan et al.
NUTRITION (2016)
Janus kinase (JAK) inhibitors in the treatment of inflammatory and neoplastic diseases
Robert Roskoski
PHARMACOLOGICAL RESEARCH (2016)
The Curcumin Analog C-150, Influencing NF-κB, UPR and Akt/Notch Pathways Has Potent Anticancer Activity In Vitro and In Vivo
Laszlo Hackler et al.
PLOS ONE (2016)
Targeting arachidonic acid pathway by natural products for cancer prevention and therapy
Nagendra Sastry Yarla et al.
SEMINARS IN CANCER BIOLOGY (2016)
Relationships among alcoholic liver disease, antioxidants, and antioxidant enzymes
Kyu-Ho Han et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2016)
Drug development in Alzheimer's disease: the path to 2025
Jeffrey Cummings et al.
ALZHEIMERS RESEARCH & THERAPY (2016)
Curcumin Attenuates Beta-Amyloid-Induced Neuroinflammation via Activation of Peroxisome Proliferator-Activated Receptor-Gamma Function in a Rat Model of Alzheimer's Disease
Zun-Jing Liu et al.
FRONTIERS IN PHARMACOLOGY (2016)
Anti-inflammatory effect of resveratrol through the suppression of NF-κB and JAK/STAT signaling pathways
Chunfang Ma et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2015)
Hippocampal neuronal cyclooxygenase-2 downstream signaling imbalance in a rat model of chronic aluminium gluconate administration
Hong Wang et al.
BEHAVIORAL AND BRAIN FUNCTIONS (2015)
Flavonoids at the pharma-nutrition interface: Is a therapeutic index in demand?
Ilaria Peluso et al.
BIOMEDICINE & PHARMACOTHERAPY (2015)
Association of Flavonoid-Rich Foods and Statins in the Management of Hypercholesterolemia: A Dangerous or Helpful Combination?
Ilaria Peluso et al.
CURRENT DRUG METABOLISM (2015)
The Role of Neuroinflammation in Dementias
Giuseppe Pasqualetti et al.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS (2015)
Reactive Oxygen Species, Redox Signaling and Neuroinflammation in Alzheimer's Disease: The NF-kappa B Connection
Upinder Kaur et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2015)
The JAK/STAT3 Pathway Is a Common Inducer of Astrocyte Reactivity in Alzheimer's and Huntington's Diseases
Lucile Ben Haim et al.
JOURNAL OF NEUROSCIENCE (2015)
Intranasal Piperine-Loaded Chitosan Nanoparticles as Brain-Targeted Therapy in Alzheimer's Disease: Optimization, Biological Efficacy, and Potential Toxicity
Yosra S. R. Elnaggar et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Effect of hesperidin on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in intracerebroventricular streptozotocin induced cognitive impairment in mice
Hayate Javed et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2015)
Neuroinflammation in Alzheimer's disease
Michael T. Heneka et al.
LANCET NEUROLOGY (2015)
Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer's Disease
Giuseppe Verdile et al.
MEDIATORS OF INFLAMMATION (2015)
Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases
Yu-Jie Zhang et al.
MOLECULES (2015)
A multi-targeted approach to suppress tumor-promoting inflammation
Abbas K. Samadi et al.
SEMINARS IN CANCER BIOLOGY (2015)
Post-mortem analysis of neuroinflammatory changes in human Alzheimer's disease
Diego Gomez-Nicola et al.
ALZHEIMERS RESEARCH & THERAPY (2015)
Tau aggregation and its interplay with amyloid-β
Rebecca M. Nisbet et al.
ACTA NEUROPATHOLOGICA (2015)
Do Astrocytes Collaborate with Neurons in Spreading the Infectious Aβ and Tau Drivers of Alzheimer's Disease?
Ilaria Dal Pra et al.
NEUROSCIENTIST (2015)
Neuroinflammation in Alzheimer's disease
Fengjin Zhang et al.
NEUROPSYCHIATRIC DISEASE AND TREATMENT (2015)
Curcumin-Loaded Nanoparticles Potently Induce Adult Neurogenesis and Reverse Cognitive Deficits in Alzheimer's Disease Model via Canonical Wnt/beta-Catenin Pathway
Shashi Kant Tiwari et al.
ACS NANO (2014)
Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease
Sergio T. Ferreira et al.
ALZHEIMERS & DEMENTIA (2014)
Apelin is transcriptionally regulated by ER stress-induced ATF4 expression via a p38 MAPK-dependent pathway
Kwon Jeong et al.
APOPTOSIS (2014)
Astrocytes and neuroinflammation in Alzheimer's disease
Emma C. Phillips et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2014)
Mechanisms and Functions of Inflammasomes
Mohamed Lamkanfi et al.
CELL (2014)
Hesperidin Alleviates Cognitive Impairment, Mitochondrial Dysfunction and Oxidative Stress in a Mouse Model of Alzheimer's Disease
Dongmei Wang et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2014)
Serum Cytokine Profile in Alzheimer's Disease Patients After Ingestion of an Antioxidant Beverage
J.M. Rubio-Perez et al.
CNS & Neurological Disorders-Drug Targets (2014)
Multifunctional Effects of Mangosteen Pericarp on Cognition in C57BL/6J and Triple Transgenic Alzheimer's Mice
Hei-Jen Huang et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2014)
Antioxidative Dietary Compounds Modulate Gene Expression Associated with Apoptosis, DNA Repair, Inhibition of Cell Proliferation and Migration
Likui Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)
Mediterranean Diet and Cognitive Decline. A Lesson from the Whole-Diet Approach: What Challenges Lie Ahead?
Vincenzo Solfrizzi et al.
JOURNAL OF ALZHEIMERS DISEASE (2014)
Effects of Curcumin (Curcuma longa) on Learning and Spatial Memory as Well as Cell Proliferation and Neuroblast Differentiation in Adult and Aged Mice by Upregulating Brain-Derived Neurotrophic Factor and CREB Signaling
Sung Min Nam et al.
JOURNAL OF MEDICINAL FOOD (2014)
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
Claudio Franceschi et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Cellular senescence: from physiology to pathology
Daniel Munoz-Espin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Alzheimer's and ABC transporters - new opportunities for diagnostics and treatment
Jens Pahnke et al.
NEUROBIOLOGY OF DISEASE (2014)
1,8-Cineole (Eucalyptol) Mitigates Inflammation in Amyloid Beta Toxicated PC12 Cells: Relevance to Alzheimer's Disease
Andleeb Khan et al.
NEUROCHEMICAL RESEARCH (2014)
Oxidative Stress in Alzheimer's Disease: Why Did Antioxidant Therapy Fail?
Torbjorn Persson et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2014)
Chemical Tuning Enhances Both Potency Toward Nrf2 and In Vitro Therapeutic Index of Triterpenoids
Ian M. Copple et al.
TOXICOLOGICAL SCIENCES (2014)
Neuroinflammation in the pathogenesis of Alzheimer's disease. A rational framework for the search of novel therapeutic approaches
Inelia Morales et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Raised Serum Proinflammatory Cytokines in Alzheimer's Disease with Depression
Aging and Disease (2014)
The Possible Role of Antioxidant Vitamin C in Alzheimer's Disease Treatment and Prevention
Jae-Hyeok Heo et al.
AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS (2013)
Microglia and neurodegeneration: The role of systemic inflammation
Colm Cunningham
GLIA (2013)
Effects of naringenin and its phase II metabolites on in vitro human macrophage gene expression
Margherita Dall'Asta et al.
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2013)
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice
Michael T. Heneka et al.
NATURE (2013)
Amelioration of cognitive impairment and neurodegeneration by catechin hydrate in rat model of streptozotocin-induced experimental dementia of Alzheimer's type
Md. Ejaz Ahmed et al.
NEUROCHEMISTRY INTERNATIONAL (2013)
Fisetin Enhances Behavioral Performances and Attenuates Reactive Gliosis and Inflammation During Aluminum Chloride-Induced Neurotoxicity
Dharmalingam Prakash et al.
NEUROMOLECULAR MEDICINE (2013)
Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology
Grietje Krabbe et al.
PLOS ONE (2013)
Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration
V. Hugh Perry et al.
SEMINARS IN IMMUNOPATHOLOGY (2013)
Inflammatory process in Alzheimer's Disease
Marco A. Meraz-Rios et al.
FRONTIERS IN INTEGRATIVE NEUROSCIENCE (2013)
Role of ABC Transporters in the Pathogenesis of Alzheimer's Disease
Alaa H. Abuznait et al.
ACS CHEMICAL NEUROSCIENCE (2012)
The Classification of Microglial Activation Phenotypes on Neurodegeneration and Regeneration in Alzheimer's Disease Brain
Megan M. Varnum et al.
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2012)
Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis
Rui Liu et al.
BMC MEDICINE (2012)
Oligomers of beta-amyloid protein (Aβ1-42) induce the activation of cyclooxygenase-2 in astrocytes via an interaction with interleukin-1beta, tumour necrosis factor-alpha, and a nuclear factor kappa-B mechanism in the rat brain
I. Carrero et al.
EXPERIMENTAL NEUROLOGY (2012)
Flavonoids, cognition, and dementia: Actions, mechanisms, and potential therapeutic utility for Alzheimer disease
Robert J. Williams et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
A Combination Cocktail Improves Spatial Attention in a Canine Model of Human Aging and Alzheimer's Disease
Elizabeth Head et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Attenuation of Aβ-induced neurotoxicity by thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress
Andleeb Khan et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2012)
Amyloid precursor protein (APP) regulates synaptic structure and function
Sheue-Houy Tyan et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2012)
Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity
Ursula Fuenfschilling et al.
NATURE (2012)
Preconditioning with Ginkgo biloba (EGb 761®) provides neuroprotection through HO1 and CRMP2
Shadia E. Nada et al.
NEUROBIOLOGY OF DISEASE (2012)
Antioxidant Therapies for Alzheimer's Disease
Ye Feng et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
Neuropathological Similarities and Differences between Schizophrenia and Bipolar Disorder: A Flow Cytometric Postmortem Brain Study
Yoshitaka Hayashi et al.
PLOS ONE (2012)
Reduced Myelin Basic Protein and Actin-Related Gene Expression in Visual Cortex in Schizophrenia
Paul R. Matthews et al.
PLOS ONE (2012)
An Alzheimer's Disease-Relevant Presenilin-1 Mutation Augments Amyloid-Beta-Induced Oligodendrocyte Dysfunction
Maya K. Desai et al.
GLIA (2011)
Amyloid-β-Induced Reactive Oxygen Species Production and Priming Are Differentially Regulated by Ion Channels in Microglia
Tom Schilling et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2011)
Complement in the brain
Robert Veerhuis et al.
MOLECULAR IMMUNOLOGY (2011)
Caspase signalling controls microglia activation and neurotoxicity
Miguel A. Burguillos et al.
NATURE (2011)
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Lydia Alvarez-Erviti et al.
NATURE BIOTECHNOLOGY (2011)
Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
Marco Prinz et al.
NATURE NEUROSCIENCE (2011)
Proinflammatory cytokines, sickness behavior, and Alzheimer disease
C. Holmes et al.
NEUROLOGY (2011)
Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation
Markus P. Kummer et al.
NEURON (2011)
Novel insights for the treatment of Alzheimer's disease
Alexander Kurz et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2011)
The neuroprotective role of boric acid on aluminum chloride-induced neurotoxicity
Suat Colak et al.
TOXICOLOGY AND INDUSTRIAL HEALTH (2011)
Disease-associated amyloid and misfolded protein aggregates activate the inflammasome
Seth L. Masters et al.
TRENDS IN MOLECULAR MEDICINE (2011)
Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture
C. J. Garwood et al.
CELL DEATH & DISEASE (2011)
Oligodendrocytes: biology and pathology
Monika Bradl et al.
ACTA NEUROPATHOLOGICA (2010)
Focal demyelination in Alzheimer's disease and transgenic mouse models
Stanislaw Mitew et al.
ACTA NEUROPATHOLOGICA (2010)
Regulation of NF-E2-Related Factor 2 Signaling for Cancer Chemoprevention: Antioxidant Coupled with Antiinflammatory
Rong Hu et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Macrophage Colony-Stimulating Factor (M-CSF) in Plasma and CSF of Patients with Mild Cognitive Impairment and Alzheimer's Disease
C. Laske et al.
CURRENT ALZHEIMER RESEARCH (2010)
CCL2 modulates cytokine production in cultured mouse astrocytes
Bridgette D. Semple et al.
JOURNAL OF NEUROINFLAMMATION (2010)
Tyk2/STAT3 Signaling Mediates β-Amyloid-Induced Neuronal Cell Death: Implications in Alzheimer's Disease
Jun Wan et al.
JOURNAL OF NEUROSCIENCE (2010)
Microglia in neurodegenerative disease
V. Hugh Perry et al.
NATURE REVIEWS NEUROLOGY (2010)
Alzheimer's Disease and tauopathy studies in flies and worms
Jill Wentzell et al.
NEUROBIOLOGY OF DISEASE (2010)
beta-Amyloid precursor protein metabolism: focus on the functions and degradation of its intracellular domain
Erica Buoso et al.
PHARMACOLOGICAL RESEARCH (2010)
Nuclear factor-κB is a critical mediator of stress-impaired neurogenesis and depressive behavior
Ja Wook Koo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease
Wolfgang J. Streit et al.
ACTA NEUROPATHOLOGICA (2009)
Interferon-γ Differentially Affects Alzheimer's Disease Pathologies and Induces Neurogenesis in Triple Transgenic-AD Mice
Michael A. Mastrangelo et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Thiol-Based Redox Switches in Eukaryotic Proteins
Nicolas Brandes et al.
ANTIOXIDANTS & REDOX SIGNALING (2009)
Dihydroxylated phenolic acids derived from microbial metabolism reduce lipopolysaccharide-stimulated cytokine secretion by human peripheral blood mononuclear cells
Maria Monagas et al.
BRITISH JOURNAL OF NUTRITION (2009)
Nox proteins in signal transduction
David I. Brown et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
STAT3 tyrosine phosphorylation is critical for interleukin 1 beta and interleukin-6 production in response to lipopolysaccharide and live bacteria
Lobelia Samavati et al.
MOLECULAR IMMUNOLOGY (2009)
Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons
T. Chiba et al.
MOLECULAR PSYCHIATRY (2009)
Allele-specific RNAi Mitigates Phenotypic Progression in a Transgenic Model of Alzheimer's Disease
Edgardo Rodriguez-Lebron et al.
MOLECULAR THERAPY (2009)
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
Jean-Charles Lambert et al.
NATURE GENETICS (2009)
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
Denise Harold et al.
NATURE GENETICS (2009)
CCR5 deficiency induces astrocyte activation, Aβ deposit and impaired memory function
Yong Kyoung Lee et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2009)
Systemic inflammation and disease progression in Alzheimer disease
C. Holmes et al.
NEUROLOGY (2009)
Immune Activation in Brain Aging and Neurodegeneration: Too Much or Too Little?
Kurt M. Lucin et al.
NEURON (2009)
Chronic Neuron-Specific Tumor Necrosis Factor-Alpha Expression Enhances the Local Inflammatory Environment Ultimately Leading to Neuronal Death in 3xTg-AD Mice
Michelle C. Janelsins et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
A comparative study of the effects of quercetin and its glucuronide and sulfate metabolites on human neutrophil function in vitro
Sunita Suri et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Complete rescue of cerebrovascular function in aged Alzheimer's disease transgenic mice by antioxidants and pioglitazone, a peroxisome proliferator-activated receptor γ agonist
Nektaria Nicolakakis et al.
JOURNAL OF NEUROSCIENCE (2008)
Microglial dysfunction and defective β-amyloid clearance pathways in aging Alzheimer's disease mice
Suzanne E. Hickman et al.
JOURNAL OF NEUROSCIENCE (2008)
Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease
Aynun N. Begum et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
c-Rel, an NF-κB family transcription factor, is required for hippocampal long-term synaptic plasticity and memory formation
Hyung Jin Ahn et al.
LEARNING & MEMORY (2008)
Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer's disease
Melanie Meyer-Luehmann et al.
NATURE (2008)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
NATURE IMMUNOLOGY (2008)
MAPK p38 regulates transcriptional activity of NF-κB in primary human astrocytes via acetylation of p65
Ramendra N. Saha et al.
JOURNAL OF IMMUNOLOGY (2007)
RNA interference as a tool for Alzheimer's disease therapy
Antonio Orlacchio et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2007)
Chemokines and chemokine receptors in neurological disease: Raise, retain, or reduce?
Carine Savarin-Vuaillat et al.
NEUROTHERAPEUTICS (2007)
Epigallocatechin-3-gallate suppresses NF-κB activation and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG cells
Su-Jin Kim et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2007)
Caspase-1 inflammasomes in infection and inflammation
Mohamed Lamkanfi et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2007)
Elevated levels of 3-nitrotyrosine in brain from subjects with amnestic mild cognitive impairment: Implications for the role of nitration in the progression of Alzheimer's disease
D. Allan Butterfield et al.
BRAIN RESEARCH (2007)
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
Yasumasa Yoshiyama et al.
NEURON (2007)
Interferon-γ and tumor necrosis factor-a regulate amyloid-α plaque deposition and β-secretase expression in Swedish mutant APP transgenic mice
Masaru Yamamoto et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Function of COX-2 and prostaglandins in neurological disease
X. Liang et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2007)
Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms
M Sastre et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2006)
Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern
T. Melnikova et al.
NEUROSCIENCE (2006)
It may take inflammation, phosphorylation and ubiquitination to tangle' in Alzheimer's disease
Lisette Arnaud et al.
NEURODEGENERATIVE DISEASES (2006)
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease
V Hirsch-Reinshagen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase
C Nathan et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration
C Cunningham et al.
JOURNAL OF NEUROSCIENCE (2005)
Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease
M Kitazawa et al.
JOURNAL OF NEUROSCIENCE (2005)
The interleukin-1 signalling pathway in astrocytes: a key contributor to inflammation in the brain
PN Moynagh
JOURNAL OF ANATOMY (2005)
Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas
TJ Mitchell et al.
IMMUNOLOGY (2005)
Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease
Nikunj S. Patel et al.
JOURNAL OF NEUROINFLAMMATION (2005)
The biology of p38 kinase: A central role in inflammation
GL Schieven
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2005)
Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK
AM Bodles et al.
NEUROBIOLOGY OF AGING (2005)
Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice
M Kawasumi et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
Importance of MAPK pathways for microglial pro-inflammatory cytokine IL-1β production
SH Kim et al.
NEUROBIOLOGY OF AGING (2004)
Tumor necrosis factor-α, interleukin-1β, and interferon-γ stimulate γ-secretase-mediated cleavage of amyloid precursor protein through a JNK-dependent MAPK pathway
YF Liao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
NG2-positive cells in the mouse white and grey matter display distinct physiological properties
R Chittajallu et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Nitric oxide-sensitive guanylyl cyclase: structure and regulation
D Koesling et al.
NEUROCHEMISTRY INTERNATIONAL (2004)
Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic
TD Warner et al.
FASEB JOURNAL (2004)
p38 MAP kinase is activated at early stages in Alzheimer's disease brain
AY Sun et al.
EXPERIMENTAL NEUROLOGY (2003)
Amyloid β peptide-induced corpus callosum damage and glial activation in vivo
N Jantaratnotai et al.
NEUROREPORT (2003)
Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains
RG Nagele et al.
BRAIN RESEARCH (2003)
Presenilin-1 mutation sensitizes oligodendrocytes to glutamate and amyloid toxicities, and exacerbates white matter damage and memory impairment in mice
K Pak et al.
NEUROMOLECULAR MEDICINE (2003)
Inflammation and therapeutic vaccination in CNS diseases
HL Weiner et al.
NATURE (2002)
β-amyloid-induced inflammation and cholinergic hypofunction in the rat brain in vivo:: Involvement of the p38MAPK pathway
MG Giovannini et al.
NEUROBIOLOGY OF DISEASE (2002)
Inflammation in neurodegenerative disease - A double-edged sword
T Wyss-Coray et al.
NEURON (2002)
Role of mitogen-activated protein kinases in inducible nitric oxide synthase and TNFα expression in human fetal astrocytes
LWL Hua et al.
JOURNAL OF NEUROIMMUNOLOGY (2002)
Activation of MKK6, an upstream activator of p38, in Alzheimer's disease
XW Zhu et al.
JOURNAL OF NEUROCHEMISTRY (2001)
Modeling microglial activation in Alzheimer's disease with human postmortem microglial cultures
LF Lue et al.
NEUROBIOLOGY OF AGING (2001)
In-vivo measurement of activated microglia in dementia
A Cagnin et al.
LANCET (2001)
Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro
LF Lue et al.
GLIA (2001)
Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration
Jin-Jing Pei et al.
JOURNAL OF ALZHEIMERS DISEASE (2001)
p38 map kinase regulates TNF-α production in human astrocytes and microglia by multiple mechanisms
YB Lee et al.
CYTOKINE (2000)
Glutamatergic synapses on oligodendrocyte precursor cells in the hippocampus
DE Bergles et al.
NATURE (2000)
β-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1β- and tumor necrosis factor-α (TNFα)-dependent, and involves a TNFα receptor-associated factor- and NFκB-inducing kinase-dependent signaling mechanism
KT Akama et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Redox regulatory mechanisms of cellular signal transduction
SP Gabbita et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2000)
Inflammation and Alzheimer's disease
H Akiyama et al.
NEUROBIOLOGY OF AGING (2000)