Rhodol-derived turn-on fluorescent probe for copper ions with high selectivity and sensitivity

A new rhodol-derived fluorescent probe 1 with picolinate as the recognition receptor was designed and simply synthesized using a one-step reaction. With the concentration of added Cu2+ increases, it gradually turns pink, so the effect of naked eye detection can be achieved. The detection limit of probe 1 for Cu2+ is 42 nM, and the linear detection range was 0-2 mu M. The experimental results showed that 1 was a fluorescent probe with high selectivity, good water solubility, and high sensitivity to Cu2+. Probe 1 was successfully applied in cell imaging experiments and can detect the concentration of Cu2+ in water samples. All these indicate that probe 1 has the potential to be applied to the detection of Cu2+ concentration in the real environment.

Automated summary

A new rhodol-derived fluorescent probe 1 with high selectivity and sensitivity for Cu2+ detection was designed and synthesized. It can detect Cu2+ concentration in water samples and cell imaging experiments, showing potential for application in real environmental detection.