4.7 Editorial Material

Immune response to SARSCoV-2 infection and vaccination in patients receiving kidney replacement therapy

Journal

KIDNEY INTERNATIONAL
Volume 99, Issue 6, Pages 1275-1279

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.kint.2021.04.007

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This issue of Kidney International summarizes the initial experience regarding the immunogenicity of prior COVID-19 infection and the response to COVID-19 vaccines among patients on maintenance dialysis and kidney transplant recipients. Preliminary data suggest durability of immune response after COVID-19 infection, with a significant portion of dialysis patients developing robust antibody titers after the second vaccine dose, while kidney transplant recipients show a less-strong immune response.
In this issue of Kidney International, the initial experience regarding the immunogenicity of prior coronavirus disease 2019 (COVID-19) infection and the response to the COVID-19 vaccines among patients on maintenance dialysis and kidney transplant recipients is summarized. Preliminary data suggest that there is durability of immune response after COVID-19 infection. Although immune response to the first dose of vaccine is less in infection-naive patients than healthy individuals in both groups, after the second vaccine dose a significant portion of patients receiving maintenance dialysis develop robust antibody titers, whereas kidney transplant recipients show a less-strong immune response.

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