4.6 Article

Moderators of cognitive insight outcome in metacognitive training for first-episode psychosis

Journal

JOURNAL OF PSYCHIATRIC RESEARCH
Volume 141, Issue -, Pages 104-110

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jpsychires.2021.06.040

Keywords

Moderators; Cognitive insight; First-episode psychosis; Metacognitive training; Gender

Categories

Funding

  1. Instituto de Salud Carlos III (Spanish Government) [PI11/01347, PI18/00212]
  2. Fondo Europeo de Desarrollo Regional (FEDER), Health Department of Catalonia [SLT006/17/00231]
  3. Progress and Health Foundation of the Andalusian Regional Ministry of Health [PI0634/2011]
  4. Obra Social La Caixa
  5. Obra Social Sant Joan de Deu (BML)
  6. CERCA Programme/Generalitat de Catalunya
  7. IDIVAL [INT/A19/02]

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Metacognitive training (MCT) is effective in improving cognitive insight in individuals with psychotic disorders, particularly in terms of reducing self-certainty. The study found that age of onset moderated self-reflectiveness, while gender and baseline self-esteem moderated the effects of MCT on self-certainty. Overall, MCT can be generalized to a variety of sociodemographic and clinical profiles, with the potential for targeted interventions based on individual characteristics.
Metacognitive training (MCT) is a promising treatment for improving cognitive insight associated with delusional beliefs in individuals with psychotic disorders. The aim of this study was to examine potential moderators of cognitive insight in individuals with first-episode psychosis (FEP) who received either MCT or psychoeducation. The present study was based on data from a randomized control trial comparing MCT to psychoeducation. Baseline sociodemographic and clinical characteristics in a sample of 122 patients with FEP were examined as potential moderators of the self-reflectiveness and self-certainty dimensions of cognitive insight using the SPSS PROCESS macro. The only variable that moderated self-reflectiveness at the post-treatment evaluation was age of onset (b = -0.27, p = .025). The effect of MCT in reducing self-certainty was stronger in women (b = -3.26, p = .018) and in individuals with average or above average baseline self-esteem (b = -0.30, p = .007). Overall, our findings support the generalization of MCT to a variety of sociodemographic and clinical profiles. While some patient profiles may require targeted interventions such as MCT to improve cognitive insight, others may do equally as well with less demanding interventions such as a psychoeducational group.

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