4.5 Review

Edge-illumination x-ray phase-contrast imaging

Journal

JOURNAL OF PHYSICS-CONDENSED MATTER
Volume 33, Issue 36, Pages -

Publisher

IOP PUBLISHING LTD
DOI: 10.1088/1361-648X/ac0e6e

Keywords

x-ray imaging; phase-contrast; x-ray masks; structured illumination

Funding

  1. EPSRC [EP/G004250/1, EP/I021884/1, EP/L001381/1, EP/T005408/1]
  2. Wellcome Trust [085856/Z/08/Z, 200137/Z/15/Z]
  3. Innovative Research Calls in Explosives and Weapons Detection 2007 (a Cross-Government programme - number of Departments and Agencies under the UK Government's CONTEST strategy)
  4. Innovative Research Calls in Explosives and Weapons Detection 2013 (a Cross-Government programme - number of Departments and Agencies under the UK Government's CONTEST strategy)
  5. Innovative Research Calls in Explosives and Weapons Detection 2016 (a Cross-Government programme - number of Departments and Agencies under the UK Government's CONTEST strategy)
  6. US Department of Homeland Security, Science and Technology Directorate
  7. EU [MEIF-CT-2004-009143]
  8. Royal Academy of Engineering through their 'Chairs in Emerging Technologies' Scheme
  9. Wellcome Trust [200137/Z/15/Z, 085856/Z/08/Z] Funding Source: Wellcome Trust
  10. EPSRC [EP/G004250/1] Funding Source: UKRI

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X-ray phase-contrast imaging (XPCI) gained popularity in the mid-90s due to the capabilities of revealing previously invisible object features. While early XPCI implementations required synchrotron facilities for efficiency, new approaches in the mid-00s allowed for XPCI with conventional x-ray sources. One promising approach is edge-illumination XPCI, which is evolving towards practical applications in contemporary XPCI research.
Although early demonstration dates back to the mid-sixties, x-ray phase-contrast imaging (XPCI) became hugely popular in the mid-90s, thanks to the advent of 3rd generation synchrotron facilities. Its ability to reveal object features that had so far been considered invisible to x-rays immediately suggested great potential for applications across the life and the physical sciences, and an increasing number of groups worldwide started experimenting with it. At that time, it looked like a synchrotron facility was strictly necessary to perform XPCI with some degree of efficiency-the only alternative being micro-focal sources, the limited flux of which imposed excessively long exposure times. However, new approaches emerged in the mid-00s that overcame this limitation, and allowed XPCI implementations with conventional, non-micro-focal x-ray sources. One of these approaches showing particular promise for 'real-world' applications is edge-illumination XPCI: this article describes the key steps in its evolution in the context of contemporary developments in XPCI research, and presents its current state-of-the-art, especially in terms of transition towards practical applications.

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