4.5 Article

Dependence of Work on the Pulling Speed in Mechanical Ligand Unbinding

Related references

Note: Only part of the references are listed.
Review Chemistry, Multidisciplinary

Atomic Force Microscopy-Based Force Spectroscopy and Multiparametric Imaging of Biomolecular and Cellular Systems

Daniel J. Mueller et al.

Summary: Over the past three decades, key technological improvements have transformed AFM into a nanoscopic laboratory for directly observing and chemically characterizing molecular and cell biological systems under physiological conditions. By customizing nanoscopic chemical laboratories and utilizing different AFM modes, it is possible to chemically image, sense, and manipulate biosystems at extremely small spatial and temporal resolutions. The combination of AFM with optical microscopy and spectroscopy shows great potential in addressing the complexity of biological systems and tackling fundamental challenges in life sciences.

CHEMICAL REVIEWS (2021)

Article Chemistry, Physical

How Good is Jarzynski's Equality for Computer-Aided Drug Design?

Kiet Ho et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2020)

Article Multidisciplinary Sciences

Heterogeneous and rate-dependent streptavidin-biotin unbinding revealed by high-speed force spectroscopy and atomistic simulations

Felix Rico et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Biochemistry & Molecular Biology

New approaches for computing ligand-receptor binding kinetics

Neil J. Bruce et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2018)

Article Chemistry, Physical

Probing the Binding Affinity by Jarzynski's Nonequilibrium Binding Free Energy and Rupture Time

Duc Toan Truong et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2018)

Article Biochemistry & Molecular Biology

Computing the binding affinity of a ligand buried deep inside a protein with the hybrid steered molecular dynamics

Oscar D. Villarreal et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)

Article Chemistry, Physical

Rate turnover in mechano-catalytic coupling: A model and its microscopic origin

Mahua Roy et al.

JOURNAL OF CHEMICAL PHYSICS (2015)

Article Biochemical Research Methods

Steered Molecular Dynamics-A Promising Tool for Drug Design

Mai Suan Li et al.

Current Bioinformatics (2013)

Article Multidisciplinary Sciences

Interpreting the widespread nonlinear force spectra of intermolecular bonds

Raymond W. Friddle et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Chemistry, Multidisciplinary

Kinetic Measurements on Single-Molecule Disulfide Bond Cleavage

Jian Liang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Chemistry, Medicinal

Top Leads for Swine Influenza A/H1N1 Virus Revealed by Steered Molecular Dynamics Approach

Binh Khanh Mai et al.

JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)

Article Chemistry, Multidisciplinary

Single-Molecule Pulling Simulations Can Discern Active from Inactive Enzyme Inhibitors

Francesco Colizzi et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)

Review Physics, Multidisciplinary

Biomolecules under mechanical force

Sanjay Kumar et al.

PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS (2010)

Article Chemistry, Physical

Absolute FKBP binding affinities obtained via nonequilibrium unbinding simulations

F. Marty Ytreberg

JOURNAL OF CHEMICAL PHYSICS (2009)

Article Multidisciplinary Sciences

Dynamics of unbinding of cell adhesion molecules: Transition from catch to slip bonds

V Barsegov et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Multidisciplinary Sciences

Hidden complexity in the mechanical properties of titin

PM Williams et al.

NATURE (2003)

Article Microbiology

Molecular analysis of beta-lactamase structure and function

FK Majiduddin et al.

INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2002)

Article Multidisciplinary Sciences

Free energy reconstruction from nonequilibrium single-molecule pulling experiments

G Hummer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)