Real-time ultrasound-guided lumbar puncture in the neonatal intensive care unit

Objective To determine the rates of traumatic lumbar puncture (LP) and overall success rates using the real-time ultrasound-guided technique when performed by a neonatal point-of-care ultrasound provider. Study design Retrospective observational study of 17 infants in the neonatal intensive care unit who underwent a real-time ultrasound-guided LP between March 2015 and November 2016. Spearman's correlation was calculated. Results The first attempt and overall success rates were 65% and 100%, respectively. The rate of nontraumatic LP was 69%. CSF RBC count was inversely correlated with both PMA (Spearman's correlation coefficient (r(s)) = -0.74, p = 0.0017) and weight (r(s) = -0.74, p = 0.0015) at the time of LP. Conclusions This study is the first to provide evidence of high success rates with real-time ultrasound-guided LP when performed by a neonatologist. Our data demonstrate feasibility in neonates over a broad range of weights, including premature infants as small as 750 g.

Automated summary

The study found high success rates of real-time ultrasound-guided LP when performed by neonatologist, with a first attempt success rate of 65% and overall success rate of 100%. There was a 69% rate of nontraumatic LP, and CSF RBC count was inversely correlated with PMA and weight at the time of LP.