Palladium-Catalyzed Reductive Aminocarbonylation of Benzylammonium Triflates with o-Nitrobenzaldehydes for the Synthesis of 3-Arylquinolin-2(1H)-ones

A palladium-catalyzed straightforward procedure for the synthesis of 3-arylquinolin-2(1H)-ones has been developed. The synthesis proceeds through a palladium-catalyzed reductive aminocarbonylation reaction of benzylic ammonium triflates with o-nitrobenzaldehydes, and a wide range of 3-arylquinolin-2(1H)-ones was obtained in moderate to good yields with very good functional group compatibility.

Automated summary

This study presents a palladium-catalyzed straightforward procedure for the synthesis of 3-arylquinolin-2(1H)-ones, which demonstrates moderate to good yields with very good functional group compatibility. The synthesis proceeds through a palladium-catalyzed reductive aminocarbonylation reaction, utilizing benzylic ammonium triflates and o-nitrobenzaldehydes as starting materials.