4.7 Article

Palladium-Catalyzed One-Pot Synthesis of Pyrroloindolines from 2-Alkynyl Arylazides and Thioacetamides

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 86, Issue 15, Pages 10360-10367

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.1c01058

Keywords

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Funding

  1. National Natural Science Foundation of China [21302096]
  2. Natural Science Foundation of Jiangsu Province [BK20171449]
  3. Qing Lan Project
  4. advanced analysis and testing center of Nanjing Forestry University

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A novel and efficient synthetic method was developed for the preparation of various pyrroloindolines from 2-alkynyl arylazides and thioacetamides. The reaction was carried out in a one-pot process under mild reaction conditions to afford the products in moderate to good yields, showing potential for use in organic synthesis.
A novel and efficient synthetic method for the preparation of various pyrroloindolines from 2-alkynyl arylazides and thioacetamides was developed. The reaction was carried out in a one-pot process under mild reaction conditions to afford the products in moderate to good yields, which has the potential to be used in organic synthesis.

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