Aromatic Ketone-Catalyzed Photochemical Synthesis of Imidazo-isoquinolinone Derivatives

We have developed an efficient photocatalytic decarboxylative radical addition/cyclization strategy to synthesize imidazo-isoquinolinone derivatives using inexpensive aromatic ketone photocatalysts. This method not only tolerates a wide range of functional groups but also works well for both alkyl and aryl radicals.

Automated summary

The method involves using inexpensive aromatic ketone photocatalysts to synthesize imidazo-isoquinolinone derivatives, tolerating a wide range of functional groups and working well for both alkyl and aryl radicals.