Journal
FORENSIC SCIENCE INTERNATIONAL
Volume 266, Issue -, Pages E27-E31Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.forsciint.2016.06.030
Keywords
Paramethoxyamphetamine (PMA); 3,4-Methylenedioxymethamphetamine (MDMA); Intoxication; Hair; GC/MS
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Funding
- National Forensic Service [2016-forensic toxicology-02]
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Paramethoxyamphetamine (PMA) is a phenethylamine derivative that is structurally related to 3,4-methylenedioxymethamphetamine (MDMA), but has higher toxicity than MDMA. Here, we report a fatal intoxication case involving PMA. A 36-year-old man was found dead in a hotel room. Toxicological analysis revealed that PMA concentrations were 0.57 and 0.59 mg/L in peripheral and heart blood, respectively. Ketamine and diazepam were also detected in his blood. Based on toxicological results and autopsy findings, the cause of death was determined to be acute fatal intoxication with PMA. Hair analysis using gas chromatography/mass spectrometry was performed and PMA was detected at a concentration of 20.1 ng/mg after methanol extraction for 20 h. This is the first report of the determination of PMA concentration in the hair from a drug abuser. (C) 2016 Elsevier Ireland Ltd. All rights reserved.
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