Related references
Note: Only part of the references are listed.Cryo-EM structure of CtBP2 confirms tetrameric architecture
Anne M. Jecrois et al.
STRUCTURE (2021)
NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP)
Jeffry C. Nichols et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Overexpression of HIPK2 removes the transrepression of proapoptotic genes mediated by the CtBP1-p300-FOXO3a complex and increases the chemosensitivity in osteosarcoma cells
Ning Duan et al.
JOURNAL OF CANCER (2021)
Interplay between cofactors and transcription factors in hematopoiesis and hematological malignancies
Zi Wang et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)
Targeting the CtBP1-FOXM1 transcriptional complex with small molecules to overcome MDR1-mediated chemoresistance in osteosarcoma cancer stem cells
Xun Chen et al.
JOURNAL OF CANCER (2021)
C-terminal of E1A binding protein 2 promotes the malignancy of osteosarcoma cells via JAK1/Stat3 signaling
Pengyun Wang et al.
JOURNAL OF CELL COMMUNICATION AND SIGNALING (2020)
RBBP8/CtIP suppresses P21 expression by interacting with CtBP and BRCA1 in gastric cancer
Yang Yu et al.
ONCOGENE (2020)
Wnt signaling in cancer: therapeutic targeting of Wnt signaling beyond β-catenin and the destruction complex
Youn-Sang Jung et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate
Preston R. Arnold et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2020)
CtBP determines ovarian cancer cell fate through repression of death receptors
Boxiao Ding et al.
CELL DEATH & DISEASE (2020)
The Monocyte-Derived Exosomal CLMAT3 Activates the CtBP2-p300-NF-κB Transcriptional Complex to Induce Proinflammatory Cytokines in ALI
Zhi Chen et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2020)
Epithelial-Mesenchymal Transition in Cancer: A Historical Overview
Domenico Ribatti et al.
TRANSLATIONAL ONCOLOGY (2020)
Transforming growth factor beta (TGF-β) is activated by the CtBP2-p300-AP1 transcriptional complex in chronic renal failure
Ping Zhou et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2020)
C-terminal binding proteins 1 and 2 in traumatic brain injury-induced inflammation and their inhibition as an approach for anti-inflammatory treatment
Hong Li et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2020)
DNA methylation is involved in the pathogenesis of osteoarthritis by regulating CtBP expression and CtBP-mediated signaling
Xiangxiang Sun et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2020)
TIAM1 promotes chemoresistance and tumor invasiveness in colorectal cancer
Daisuke Izumi et al.
CELL DEATH & DISEASE (2019)
Long noncoding RNA GAS5 modulates α-Solanine-induced radiosensitivity by negatively regulating miR-18a in human prostate cancer cells
Jinhui Yang et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
The CtBP1-p300-FOXO3a transcriptional complex represses the expression of the apoptotic regulators Bax and Bim in human osteosarcoma cells
Chen Li et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Active-Site Tryptophan, the Target of Antineoplastic C-Terminal Binding Protein Inhibitors, Mediates Inhibitor Disruption of CtBP Oligomerization and Transcription Coregulatory Activities
M. Michael Dcona et al.
MOLECULAR PHARMACOLOGY (2019)
ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development
Huanhuan Wang et al.
CELL REPORTS (2019)
Novel Tumor Suppressor lncRNA Growth Arrest-Specific 5 (GAS5) In Human Cancer
Yaya Yu et al.
ONCOTARGETS AND THERAPY (2019)
CtBP-a targetable dependency for tumor-initiating cell activity and metastasis in pancreatic adenocarcinoma
Ayesha T. Chawla et al.
ONCOGENESIS (2019)
CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-β signaling
Zhiqiang Zhao et al.
ONCOGENE (2019)
Intestinal Neurod1 expression impairs paneth cell differentiation and promotes enteroendocrine lineage specification
Hui Joyce Li et al.
SCIENTIFIC REPORTS (2019)
Wnt Signaling and Its Significance Within the Tumor Microenvironment: Novel Therapeutic Insights
Sonal Patel et al.
FRONTIERS IN IMMUNOLOGY (2019)
Downregulation of miR-199a-3p mediated by the CtBP2-HDAC1-FOXP3 transcriptional complex contributes to acute lung injury by targeting NLRP1
Zhi Chen et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)
The CtBP1-HDAC1/2-1RF1 transcriptional complex represses the expression of the long noncoding RNA GAS5 in human osteosarcoma cells
Xinliang Zhang et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)
NSC 95397 Suppresses Proliferation and Induces Apoptosis in Colon Cancer Cells through MKP-1 and the ERK1/2 Pathway
Navneet Kumar Dubey et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Assembly of human C-terminal binding protein (CtBP) into tetramers
Andrew G. Bellesis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
The functions and regulation of the PTEN tumour suppressor: new modes and prospects
Yu-Ru Lee et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Eukaryotic core promoters and the functional basis of transcription initiation
Vanja Haberle et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
MicroRNA485-3p negatively regulates the transcriptional co-repressor CtBP1 to control the oncogenic process in osteosarcoma cells
Kaili Du et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2018)
Kruppel-Like Factors Crippling and Uncrippling Metabolic Pathways
Nina M. Pollak et al.
JACC-BASIC TO TRANSLATIONAL SCIENCE (2018)
The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex
Wentao Zhang et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2018)
Epithelial-mesenchymal transition in tumor metastasis
Kay T. Yeung et al.
MOLECULAR ONCOLOGY (2017)
Wnt/beta-catenin pathway: modulating anticancer immune response
Sachin Gopalkrishna Pai et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
The Role of CtBP1 in Oncogenic Processes and Its Potential as a Therapeutic Target
Melanie A. Blevins et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia
E. T. Sumner et al.
ONCOGENE (2017)
The Different Mechanisms of Cancer Drug Resistance: A Brief Review
Behzad Mansoori et al.
ADVANCED PHARMACEUTICAL BULLETIN (2017)
CtBP- an emerging oncogene and novel small molecule drug target: Advances in the understanding of its oncogenic action and identification of therapeutic inhibitors
M. Michael Dcona et al.
CANCER BIOLOGY & THERAPY (2017)
Kruppel-like factors in mammalian stem cells and development
Agnieszka B. Bialkowska et al.
DEVELOPMENT (2017)
The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers
Chenhui Ma et al.
TUMOR BIOLOGY (2016)
Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP)
Sudha Korwar et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2016)
Stimulation of Suicidal Erythrocyte Death by the CDC25 Inhibitor NSC-95397
Mohamed Jemaa et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2016)
Expression and prognostic significance of CTBP2 in human gliomas
Yong Wang et al.
ONCOLOGY LETTERS (2016)
Pinin interacts with C-terminal binding proteins for RNA alternative splicing and epithelial cell identity of human ovarian cancer cells
Yanli Zhang et al.
Oncotarget (2016)
TGF-β signaling in the kidney: profibrotic and protective effects
Angara Sureshbabu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2016)
Structure-Guided Design of a High Affinity Inhibitor to Human CtBP
Brendan J. Hilbert et al.
ACS CHEMICAL BIOLOGY (2015)
Phosphorylation of Kruppel-like Factor 3 (KLF3/BKLF) and C-terminal Binding Protein 2 (CtBP2) by Homeodomain-interacting Protein Kinase 2 (HIPK2) Modulates KLF3 DNA Binding and Activity
Vitri Dewi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
MCRIP1, an ERK Substrate, Mediates ERK-Induced Gene Silencing during Epithelial-Mesenchymal Transition by Regulating the Co-Repressor CtBP
Kenji Ichikawa et al.
MOLECULAR CELL (2015)
TGF-β/Smad signaling in renal fibrosis
Xiao-Ming Meng et al.
FRONTIERS IN PHYSIOLOGY (2015)
Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression
Melanie A. Blevins et al.
JOURNAL OF BIOMOLECULAR SCREENING (2015)
Inhibition of C-terminal binding protein attenuates transcription factor 4 signaling to selectively target colon cancer stem cells
Jagrut Patel et al.
CELL CYCLE (2014)
Transcriptional Mechanisms Link Epithelial Plasticity to Adhesion and Differentiation of Epidermal Progenitor Cells
Briana Lee et al.
DEVELOPMENTAL CELL (2014)
Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design
Brendan J. Hilbert et al.
FEBS LETTERS (2014)
ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes
Lisa D. Boxer et al.
GENES & DEVELOPMENT (2014)
CtBP and Associated LSD1 Are Required for Transcriptional Activation by NeuroD1 in Gastrointestinal Endocrine Cells
Subir K. Ray et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
Transcriptional Regulation and Its Misregulation in Disease
Tong Ihn Lee et al.
CELL (2013)
CtBP1 Is Expressed in Melanoma and Represses the Transcription of p16INK4a and Brca1
Hui Deng et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2013)
C-terminal binding protein-2 regulates response of epithelial ovarian cancer cells to histone deacetylase inhibitors
L. Barroilhet et al.
ONCOGENE (2013)
A cyclic peptide inhibitor of C-terminal binding protein dimerization links metabolism with mitotic fidelity in breast cancer cells
Charles N. Birts et al.
CHEMICAL SCIENCE (2013)
BRCA1 Expression Is Epigenetically Repressed in Sporadic Ovarian Cancer Cells by Overexpression of C-Terminal Binding Protein 2
Taymaa May et al.
NEOPLASIA (2013)
Recruitment of histone deacetylases HDAC1 and HDAC2 by the transcriptional repressor ZEB1 downregulates E-cadherin expression in pancreatic cancer
Ali Aghdassi et al.
GUT (2012)
A Quantitative High-Throughput In Vitro Splicing Assay Identifies Inhibitors of Spliceosome Catalysis
Michael G. Berg et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Differential Spatial Expression and Subcellular Localization of CtBP Family Members in Rodent Brain
Diana Huebler et al.
PLOS ONE (2012)
Role of Transcriptional Corepressor CtBP1 in Prostate Cancer Progression
Rui Wang et al.
NEOPLASIA (2012)
Expression of CtBP family protein isoforms in breast cancer and their role in chemoresistance
Charles N. Birts et al.
BIOLOGY OF THE CELL (2011)
ZEB1 and CtBP form a repressive complex at a distal promoter element of the BCL6 locus
Vasiliki Papadopoulou et al.
BIOCHEMICAL JOURNAL (2010)
PDZ domains and their binding partners: structure, specificity, and modification
Ho-Jin Lee et al.
CELL COMMUNICATION AND SIGNALING (2010)
Therapeutic targeting of C-terminal binding protein in human cancer
Michael W. Straza et al.
CELL CYCLE (2010)
An ARF/CtBP2 complex regulates BH3-only gene expression and p53-independent apoptosis
R. C. Kovi et al.
CELL DEATH AND DIFFERENTIATION (2010)
Acute Lung Injury: Epidemiology, Pathogenesis, and Treatment
Elizabeth R. Johnson et al.
JOURNAL OF AEROSOL MEDICINE AND PULMONARY DRUG DELIVERY (2010)
Transcriptional regulation of BRCA1 expression by a metabolic switch
Li-Jun Di et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Interaction of ZEB and Histone Deacetylase with the PLDLS-binding cleft region of monomeric C-terminal Binding Protein 2
Ling-Jun Zhao et al.
BMC MOLECULAR BIOLOGY (2009)
The Transcriptional Corepressor CtBP: A Foe of Multiple Tumor Suppressors
G. Chinnadurai
CANCER RESEARCH (2009)
Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP
Peter Pelka et al.
NUCLEIC ACIDS RESEARCH (2009)
COOH-terminal binding protein regulates expression of the p16INK4A tumor suppressor and senescence in primary human cells
Edmund A. Mroz et al.
CANCER RESEARCH (2008)
Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3
Rachel K. Bruton et al.
JOURNAL OF VIROLOGY (2008)
Targeted disruption of the basic Kruppel-like factor gene (Klf3) reveals a role in adipogenesis
Nancy Sue et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
ZNF198 Stabilizes the LSD1-CoREST-HDAC1 Complex on Chromatin through Its MYM-Type Zinc Fingers
Christian B. Gocke et al.
PLOS ONE (2008)
The alternative reading frame tumor suppressor antagonizes hypoxia-induced cancer cell migration via interaction with the COOH-terminal binding protein corepressor
Seema Paliwal et al.
CANCER RESEARCH (2007)
Involvement of CtBP1 in the transcriptional activation of the MDR1 gene in human multildrug resistant cancer cells
Wei Jin et al.
BIOCHEMICAL PHARMACOLOGY (2007)
The effect of CtBP1 binding on the structure of the C-terminal region of adenovirus 12 early region 1A
David P. Molloy et al.
VIROLOGY (2007)
2-Keto-4-methylthiobutyrate, an intermediate in the methionine salvage pathway, is a good substrate for CtBP1
Younes Achouri et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Transcriptional regulation by C-terminal binding proteins
G. Chinnadurai
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2007)
C-Jun NH2-terminal kinase promotes apoptosis by down-regulating the transcriptional co-repressor CtBP
Su-Yan Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins
Kate G. R. Quinlan et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Role of the C-terminal binding protein PXDLS motif binding cleft in protein interactions and transcriptional repression
Kate G. R. Quinlan et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas
Cristina Pena et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells
Meghan E. Minard et al.
CLINICAL & EXPERIMENTAL METASTASIS (2006)
The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured
M Nardini et al.
PROTEIN SCIENCE (2006)
Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis
S Paliwal et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Acetylation by p300 regulates nuclear localization and function of the transcriptional corepressor CtBP2
LJ Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Corepressor CtBP1 interacts with and specifically inhibits CBP activity
V Senyuk et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2005)
CtBP represses p300-mediated transcriptional activation by direct association with its bromodomain
JH Kim et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)
Regulation of BRCA2 gene expression by the SLUG repressor protein in human breast cells
MK Tripathi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Homeodomain-interacting protein kinase-2 mediates CtBP phosphorylation and degradation in UV-triggered apoptosis
QH Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Kruppel-like zinc finger protein Gli-similar 2 (Glis2) represses transcription through interaction with C-terminal binding protein 1 (CtBP1)
SC Kim et al.
NUCLEIC ACIDS RESEARCH (2005)
Histone demethylation mediated by the nuclear arnine oxidase homolog LSD1
YJ Shi et al.
CELL (2004)
The biology and clinical relevance of the PTEN tumor suppressor pathway
I Sansal et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
The APC tumor suppressor binds to C-terminal binding protein to divert nuclear β-catenin from TCF
F Hamada et al.
DEVELOPMENTAL CELL (2004)
Cytokine-mediated inflammation in acute lung injury
RB Goodman et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2003)
CtBP/BARS:: a dual-function protein involved in transcription co-repression, and Golgi membrane fission
M Nardini et al.
EMBO JOURNAL (2003)
Coordinated histone modifications mediated by a CtBP co-repressor complex
YJ Shi et al.
NATURE (2003)
C-terminal-binding protein corepresses epithelial and proapoptotic gene expression programs
M Grooteclaes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and -independent mechanisms
I Fernandes et al.
MOLECULAR CELL (2003)
Two nonconsensus sites in the Epstein-Barr virus oncoprotein EBNA3A cooperate to bind the co-repressor carboxyl-terminalbinding protein (CtBP)
M Hickabottom et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development.
JD Hildebrand et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
The leukemia-associated transcription repressor AML1/MDS1/EVI1 requires CtBP to induce abnormal growth and differentiation of murine hematopoietic cells
V Senyuk et al.
ONCOGENE (2002)
Association of COOH-terminal-binding protein (CtBP) and MEF2-interacting transcription repressor (MITR) contributes to transcriptional repression of the MEF2 transcription factor
CL Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The multiple roles of PTEN in tumor suppression
A Di Cristofano et al.
CELL (2000)
Share Paper
