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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
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Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin α-2 Expression, and Induce Antitumor Effects against Human Glioma
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JOURNAL OF MEDICINAL CHEMISTRY (2015)
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JOURNAL OF MEDICINAL CHEMISTRY (2015)
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ORGANIC & BIOMOLECULAR CHEMISTRY (2015)
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
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ACS CHEMICAL BIOLOGY (2014)
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ACTA PHARMACOLOGICA SINICA (2014)
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Jong Hyun Lee et al.
CANCER LETTERS (2014)
Shikonin suppresses IL-17-induced VEGF expression via blockage of JAK2/STAT3 pathway
Yuanyuan Xu et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2014)
Effect of the STAT3 inhibitor STX-0119 on the proliferation of a temozolomide-resistant glioblastoma cell line
Tadashi Ashizawa et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2014)
Galiellalactone Is a Direct Inhibitor of the Transcription Factor STAT3 in Prostate Cancer Cells
Nicholas Don-Doncow et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
UPLC/MS/MS method for quantification and cytotoxic activity of sesquiterpene lactones isolated from Saussurea lappa
Ashish Kumar et al.
JOURNAL OF ETHNOPHARMACOLOGY (2014)
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
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NATURE REVIEWS CANCER (2014)
JAB1 regulates unphosphorylated STAT3 DNA-binding activity through protein-protein interaction in human colon cancer cells
Arata Nishimoto et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
The STAT3 Inhibitor Stattic Impairs Cardiomyocyte Mitochondrial Function Through Increased Reactive Oxygen Species Formation
Kerstin Boengler et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography
Edwin Nkansah et al.
FEBS LETTERS (2013)
Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma
Tadashi Ashizawa et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2013)
Novel Nitrogen-Enriched Oridonin Analogues with Thiazole-Fused A-Ring: Protecting Group-Free Synthesis, Enhanced Anticancer Profile, and Improved Aqueous Solubility
Chunyong Ding et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Inhibiting Aberrant Signal Transducer and Activator of Transcription Protein Activation with Tetrapodal, Small Molecule Src Homology 2 Domain Binders: Promising Agents against Multiple Myeloma
Brent D. G. Page et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
A Review on Anti-Inflammatory Activity of Monoterpenes
Rita de Cassia da Silveira e Sa et al.
MOLECULES (2013)
Emerging molecular targets in melanoma invasion and metastasis
Jose L. Orgaz et al.
PIGMENT CELL & MELANOMA RESEARCH (2013)
Discovery of O-Alkylamino-Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents
Haijun Chen et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma
Sina Haftchenary et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
GSTP1 negatively regulates Stat3 activation in epidermal growth factor signaling
Xianjuan Kou et al.
ONCOLOGY LETTERS (2013)
Suppressive Effects of Plumbagin on Invasion and Migration of Breast Cancer Cells via the Inhibition of STAT3 Signaling and Down-regulation of Inflammatory Cytokine Expressions
Wei Yan et al.
BONE RESEARCH (2013)
STAT3 inhibition, a novel approach to enhancing targeted therapy in human cancers
Xiaochun Wang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2012)
Mechanisms of Unphosphorylated STAT3 Transcription actor Binding to DNA
Olga A. Timofeeva et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Small Molecule STAT5-SH2 Domain Inhibitors Exhibit Potent Antileukemia Activity
Brent D. G. Page et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Small Molecule Inhibitors of Signal Transducer and Activator of Transcription 3 (Stat3) Protein
Bikash Debnath et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Piceatannol inhibits migration and invasion of prostate cancer cells: possible mediation by decreased interleukin-6 signaling
Gyoo Taik Kwon et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2012)
Acetylated STAT3 is crucial for methylation of tumor-suppressor gene promoters and inhibition by resveratrol results in demethylation
Heehyoung Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
Xiaolei Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
First-in-Human Trial of a STAT3 Decoy Oligonucleotide in Head and Neck Tumors: Implications for Cancer Therapy
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CANCER DISCOVERY (2012)
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Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways
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JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies
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A novel small-molecule disrupts Stat3 SH2 domain-phosphotyrosine interactions and Stat3-dependent tumor processes
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BIOCHEMICAL PHARMACOLOGY (2010)
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CANCER RESEARCH (2010)
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells
Li Lin et al.
MOLECULAR CANCER (2010)
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Kenji Matsuno et al.
ACS MEDICINAL CHEMISTRY LETTERS (2010)
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NATURE REVIEWS CANCER (2009)
Development of a STAT3 reporter prostate cancer cell line for high throughput screening of STAT3 activators and inhibitors
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)
Michal Marzec et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
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