Related references
Note: Only part of the references are listed.Adenosine A2Areceptor antagonists: from caffeine to selective non-xanthines
Kenneth A. Jacobson et al.
BRITISH JOURNAL OF PHARMACOLOGY (2022)
Ryanodine Receptors: A Potential Treatment Target in Various Neurodegenerative Disease
Liang Sun et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2021)
Metabolism and Mechanism of Human Cytochrome P450 Enzyme 1A2
Jingchao Guo et al.
CURRENT DRUG METABOLISM (2021)
Medicinal chemistry of P2 and adenosine receptors: Common scaffolds adapted for multiple targets
Kenneth A. Jacobson et al.
BIOCHEMICAL PHARMACOLOGY (2021)
Caffeine-clozapine interaction associated with severe toxicity and multiorgan system failure: a case report
Alex Yartsev et al.
BMC PSYCHIATRY (2021)
Energy drink-induced cardiomyopathy
Gracie Fisk et al.
BMJ CASE REPORTS (2021)
Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer
Lawrence Fong et al.
CANCER DISCOVERY (2020)
Assessment of the nail penetration of antifungal agents, with different physico-chemical properties
Heather Davies-Strickleton et al.
PLOS ONE (2020)
RyR1-targeted drug discovery pipeline integrating FRET-based high-throughput screening and human myofiber dynamic Ca2+ assays
Robyn T. Rebbeck et al.
SCIENTIFIC REPORTS (2020)
Novel, Dual Target-Directed Annelated Xanthine Derivatives Acting on Adenosine Receptors and Monoamine Oxidase B
Kamil J. Kuder et al.
CHEMMEDCHEM (2020)
Caffeine and Doping-What Have We Learned since 2004
Patrick Diel
NUTRIENTS (2020)
Caffeine inhibits Notum activity by binding at the catalytic pocket
Yuguang Zhao et al.
COMMUNICATIONS BIOLOGY (2020)
Ryanodine receptor 1-related disorders: an historical perspective and proposal for a unified nomenclature
Tokunbor A. Lawal et al.
SKELETAL MUSCLE (2020)
Acute kidney injury and hepatitis associated with energy drink consumption: a case report
Raed Al Yacoub et al.
JOURNAL OF MEDICAL CASE REPORTS (2020)
Development of Adenosine A2A Receptor Antagonists for the Treatment of Parkinson's Disease: A Recent Update and Challenge
Jiyue Zheng et al.
ACS CHEMICAL NEUROSCIENCE (2019)
Development of Covalent Ligands for G Protein-Coupled Receptors: A Case for the Human Adenosine A3 Receptor
Xue Yang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Caffeine inhibits PI3K and mTORC2 in Dictyostelium and differentially affects multiple other cAMP chemoattractant signaling effectors
A. F. M. Tariqul Islam et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2019)
Novel multi-target directed ligands based on annelated xanthine scaffold with aromatic substituents acting on adenosine receptor and monoamine oxidase B. Synthesis, in vitro and in silico studies
Michal Zaluski et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2019)
Dantrolene Requires Mg2+ and ATP To Inhibit the Ryanodine Receptor
Gyula Diszhazi et al.
MOLECULAR PHARMACOLOGY (2019)
Modulation of cardiac ryanodine receptor 2 by calmodulin
Deshun Gong et al.
NATURE (2019)
Structural development of a type-1 ryanodine receptor (RyR1) Ca2+-release channel inhibitor guided by endoplasmic reticulum Ca2+ assay
Shuichi Mori et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
The insecticide chlorantraniliprole is a weak activator of mammalian skeletal ryanodine receptor/Ca2+ release channel
Jian Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)
Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators
Ximin Chi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Effect of Caffeine on the Bioavailability and Pharmacokinetics of an Acetylsalicylic Acid-Paracetamol Combination: Results of a Phase I Study
Thomas Weiser et al.
ADVANCES IN THERAPY (2019)
DrugBank 5.0: a major update to the DrugBank database for 2018
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2018)
Energy Drinks: A Contemporary Issues Paper
John P. Higgins et al.
CURRENT SPORTS MEDICINE REPORTS (2018)
Efficient High-Throughput Screening by Endoplasmic Reticulum Ca2+ Measurement to Identify Inhibitors of Ryanodine Receptor Ca2+-Release Channels
Takashi Murayama et al.
MOLECULAR PHARMACOLOGY (2018)
Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease
Antonio C. Silva et al.
NEUROBIOLOGY OF DISEASE (2018)
A novel pharmacological activity of caffeine in the cholinergic system
Camila Fabiani et al.
NEUROPHARMACOLOGY (2018)
Interindividual Differences in Caffeine Metabolism and Factors Driving Caffeine Consumption
Astrid Nehlig
PHARMACOLOGICAL REVIEWS (2018)
Associations of maternal caffeine intake with birth outcomes: results from the Lifeways Cross Generation Cohort Study
Ling-Wei Chen et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2018)
The Adenosinergic Signaling: A Complex but Promising Therapeutic Target for Alzheimer's Disease
Lucrezia Cellai et al.
FRONTIERS IN NEUROSCIENCE (2018)
Acute caffeine supplementation in combat sports: a systematic review
Luis M. Lopez-Gonzalez et al.
JOURNAL OF THE INTERNATIONAL SOCIETY OF SPORTS NUTRITION (2018)
Ryanodine Receptor 1-Related Myopathies: Diagnostic and Therapeutic Approaches
Tokunbor A. Lawal et al.
NEUROTHERAPEUTICS (2018)
Chronic coffee consumption and respiratory disease: A systematic review
Tiago M. Alfaro et al.
CLINICAL RESPIRATORY JOURNAL (2018)
NOTUM Is Involved in the Progression of Colorectal Cancer
Jong Hyuk Yoon et al.
CANCER GENOMICS & PROTEOMICS (2018)
High-Throughput Screens to Discover Small-Molecule Modulators of Ryanodine Receptor Calcium Release Channels
Robyn T. Rebbeck et al.
SLAS DISCOVERY (2017)
Design and synthesis of novel xanthine derivatives as potent and selective A2B adenosine receptor antagonists for the treatment of chronic inflammatory airway diseases
Sujay Basu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
A2B adenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives
Sujay Basu et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children
Daniele Wikoff et al.
FOOD AND CHEMICAL TOXICOLOGY (2017)
Caffeine in the management of patients with headache
Richard B. Lipton et al.
JOURNAL OF HEADACHE AND PAIN (2017)
Structure-Affinity Relationships and Structure-Kinetics Relationships of Pyrido[2,1-f]purine-2,4-dione Derivatives as Human Adenosine A3 Receptor Antagonists
Lizi Xia et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity
Robert K. Y. Cheng et al.
STRUCTURE (2017)
Association between coffee or caffeine consumption and fecundity and fertility: a systematic review and dose-response meta-analysis
Julie Lyngso et al.
CLINICAL EPIDEMIOLOGY (2017)
Notum coordinates synapse development via extracellular regulation of Wingless trans-synaptic signaling
Danielle L. Kopke et al.
DEVELOPMENT (2017)
Structural Basis for Gating and Activation of RyR1
Amedee des Georges et al.
CELL (2016)
Pharmacokinetic analysis and comparison of caffeine administered rapidly or slowly in coffee chilled or hot versus chilled energy drink in healthy young adults
John R. White et al.
CLINICAL TOXICOLOGY (2016)
Glycogen phosphorylase inhibitors: a patent review (2013-2015)
Marion Donnier-Marechal et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2016)
PDEStrIAn: A Phosphodiesterase Structure and Ligand Interaction Annotated Database As a Tool for Structure-Based Drug Design
Chimed Jansen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Medicinal chemistry of adenosine, P2Y and P2X receptors
Kenneth A. Jacobson et al.
NEUROPHARMACOLOGY (2016)
Convergent evolution of caffeine in plants by co-option of exapted ancestral enzymes
Ruiqi Huang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Caffeine: Friend or Foe?
Candace Doepker et al.
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 7 (2016)
A(2A) adenosine receptor deletion is protective in a mouse model of Tauopathy
C. Laurent et al.
MOLECULAR PSYCHIATRY (2016)
Association of Coffee Consumption With Total and Cause-Specific Mortality in 3 Large Prospective Cohorts
Ming Ding et al.
CIRCULATION (2015)
Caffeine: Cognitive and Physical Performance Enhancer or Psychoactive Drug?
Simone Cappelletti et al.
CURRENT NEUROPHARMACOLOGY (2015)
Notum Is Required for Neural and Head Induction via Wnt Deacylation, Oxidation, and Inactivation
Xinjun Zhang et al.
DEVELOPMENTAL CELL (2015)
Notum deacylates Wnt proteins to suppress signalling activity
Satoshi Kakugawa et al.
NATURE (2015)
Novel insights into Notum and glypicans regulation in colorectal cancer
Mariangela De Robertis et al.
ONCOTARGET (2015)
Maternal Caffeine Consumption during Pregnancy and Risk of Low Birth Weight: A Dose-Response Meta-Analysis of Observational Studies
Jongeun Rhee et al.
PLOS ONE (2015)
Cardiovascular Complications of Energy Drinks
John P. Higgins et al.
BEVERAGES (2015)
The A3 Adenosine Receptor: History and Perspectives
Pier Andrea Borea et al.
PHARMACOLOGICAL REVIEWS (2015)
Review of Published Cases of Adverse Cardiovascular Events After Ingestion of Energy Drinks
Michael Goldfarb et al.
AMERICAN JOURNAL OF CARDIOLOGY (2014)
Maternal caffeine intake during pregnancy is associated with risk of low birth weight: a systematic review and dose-response meta-analysis
Ling-Wei Chen et al.
BMC MEDICINE (2014)
Long-Term Coffee Consumption and Risk of Cardiovascular Disease A Systematic Review and a Dose-Response Meta-Analysis of Prospective Cohort Studies
Ming Ding et al.
CIRCULATION (2014)
Reproductive factors and Parkinson's disease risk in Danish women
N. Greene et al.
EUROPEAN JOURNAL OF NEUROLOGY (2014)
Dose-response meta-analysis on coffee, tea and caffeine consumption with risk of Parkinson's disease
Hui Qi et al.
GERIATRICS & GERONTOLOGY INTERNATIONAL (2014)
Prenatal caffeine intake differently affects synaptic proteins during fetal brain development
Sabrina Mioranzza et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2014)
Adenosine A2A Receptor as a Drug Discovery Target
Manuel de Lera Ruiz et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Involvement of α7 nAChR Signaling Cascade in Epigallocatechin Gallate Suppression of β-Amyloid-Induced Apoptotic Cortical Neuronal Insults
Xijing Zhang et al.
MOLECULAR NEUROBIOLOGY (2014)
DrugBank 4.0: shedding new light on drug metabolism
Vivian Law et al.
NUCLEIC ACIDS RESEARCH (2014)
The ChEMBL bioactivity database: an update
A. Patricia Bento et al.
NUCLEIC ACIDS RESEARCH (2014)
Eudistomin D and Penaresin Derivatives as Modulators of Ryanodine Receptor Channels and Sarcoplasmic Reticulum Ca2+ ATPase in Striated Muscle
Paula L. Diaz-Sylvester et al.
MOLECULAR PHARMACOLOGY (2014)
Caffeine as an analgesic adjuvant for acute pain in adults
Christopher J. Derry et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2014)
Caffeine Reduces Myocardial Blood Flow During Exercise
John P. Higgins et al.
AMERICAN JOURNAL OF MEDICINE (2013)
Maternal caffeine intake during pregnancy is associated with birth weight but not with gestational length: results from a large prospective observational cohort study
Verena Sengpiel et al.
BMC MEDICINE (2013)
Istradefylline: First Global Approval
Rosselle Dungo et al.
DRUGS (2013)
Glycogen phosphorylase inhibitors: a patent review (2008-2012)
Nicolas Gaboriaud-Kolar et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2013)
Caffeine Inhibits Acetylcholinesterase, But Not Butyrylcholinesterase
Miroslav Pohanka et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
The effect of caffeine on working memory load-related brain activation in middle-aged males
Elissa B. Klaassen et al.
NEUROPHARMACOLOGY (2013)
ACUTE CAFFEINE ADMINISTRATION IMPACT ON WORKING MEMORY-RELATED BRAIN ACTIVATION AND FUNCTIONAL CONNECTIVITY IN THE ELDERLY: A BOLD AND PERFUSION MRI STUDY
S. Haller et al.
NEUROSCIENCE (2013)
The Impact of Green Tea and Coffee Consumption on the Reduced Risk of Stroke Incidence in Japanese Population The Japan Public Health Center-Based Study Cohort
Yoshihiro Kokubo et al.
STROKE (2013)
RYR1 Mutations as a Cause of Ophthalmoplegia, Facial Weakness, and Malignant Hyperthermia
Sherin Shaaban et al.
JAMA OPHTHALMOLOGY (2013)
Structure-Based Identification of OATP1B1/3 Inhibitors
Tom De Bruyn et al.
MOLECULAR PHARMACOLOGY (2013)
Preclinical Strategy to Reduce Clinical Hepatotoxicity Using in Vitro Bioactivation Data for >200 Compounds
Melanie Z. Sakatis et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2012)
Novel 1,3-Dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as Potent and Selective A2B Adenosine Receptor Antagonists
Pier Giovanni Baraldi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Association of Coffee Drinking with Total and Cause-Specific Mortality
Neal D. Freedman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Structural Basis of Wnt Recognition by Frizzled
Claudia Y. Janda et al.
SCIENCE (2012)
Small molecules targeting phosphoinositide 3-kinases
Peng Wu et al.
MEDCHEMCOMM (2012)
Inhibition of acetylcholinesterase by green and white tea and their simulated intestinal metabolites
Edward J. Okello et al.
FOOD & FUNCTION (2012)
Mitigating the Inhibition of Human Bile Salt Export Pump by Drugs: Opportunities Provided by Physicochemical Property Modulation, In Silico Modeling, and Structural Modification
Daniel J. Warner et al.
DRUG METABOLISM AND DISPOSITION (2012)
Energy Drink Consumption and Increased Risk for Alcohol Dependence
Amelia M. Arria et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2011)
Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition
Shinji Saiki et al.
AUTOPHAGY (2011)
Coffee, green tea, black tea and oolong tea consumption and risk of mortality from cardiovascular disease in Japanese men and women
Yohei Mineharu et al.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH (2011)
Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine
Andrew S. Dore et al.
STRUCTURE (2011)
Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption
Marilyn C. Cornelis et al.
PLOS GENETICS (2011)
Lifestyle Practices and Cardiovascular Disease Mortality in the Elderly: The Leisure World Cohort Study
Annlia Paganini-Hill
CARDIOLOGY RESEARCH AND PRACTICE (2011)
Identification of small molecule compounds with higher binding affinity to guanine deaminase (cypin) than guanine
Jose R. Fernandez et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Caffeine and the Control of Cerebral Hemodynamics
Dale A. Pelligrino et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Caffeine Exposure and the Risk of Parkinson's Disease: A Systematic Review and Meta-Analysis of Observational Studiess
Joao Costa et al.
JOURNAL OF ALZHEIMERS DISEASE (2010)
Caffeine (1, 3, 7-trimethylxanthine) in Foods: A Comprehensive Review on Consumption, Functionality, Safety, and Regulatory Matters
Melanie A. Heckman et al.
JOURNAL OF FOOD SCIENCE (2010)
Coffee Consumption and Mortality Due to All Causes, Cardiovascular Disease, and Cancer in Japanese Women
Kemmyo Sugiyama et al.
JOURNAL OF NUTRITION (2010)
Energy Beverages: Content and Safety
John P. Higgins et al.
MAYO CLINIC PROCEEDINGS (2010)
Methylxanthine treatment for apnoea in preterm infants
David J. Henderson-Smart et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2010)
Green Tea Consumption and Mortality among Japanese Elderly People: The Prospective Shizuoka Elderly Cohort
Etsuji Suzuki et al.
ANNALS OF EPIDEMIOLOGY (2009)
Anthranilimide based glycogen phosphorylase inhibitors for the treatment of type 2 diabetes. Part 3: X-ray crystallographic characterization, core and urea optimization and in vivo efficacy
Stephen A. Thomson et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)
Regulation of cerebrospinal fluid production by caffeine consumption
Myoung-Eun Han et al.
BMC NEUROSCIENCE (2009)
Midlife Coffee and Tea Drinking and the Risk of Late-Life Dementia: A Population-Based CAIDE Study
Marjo H. Eskelinen et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Caffeine Reverses Cognitive Impairment and Decreases Brain Amyloid-β Levels in Aged Alzheimer's Disease Mice
Gary W. Arendash et al.
JOURNAL OF ALZHEIMERS DISEASE (2009)
Mobilization of Calcium from Intracellular Stores Facilitates Somatodendritic Dopamine Release
Jyoti C. Patel et al.
JOURNAL OF NEUROSCIENCE (2009)
A2B adenosine receptors in immunity and inflammation
Gyoergy Hasko et al.
TRENDS IN IMMUNOLOGY (2009)
Pentoxifylline for alcoholic hepatitis
Kate Whitfield et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2009)
Maternal caffeine consumption during pregnancy and the risk of miscarriage: a prospective cohort study
Xiaoping Weng et al.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2008)
The relationship of coffee consumption with mortality
Esther Lopez-Garcia et al.
ANNALS OF INTERNAL MEDICINE (2008)
1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor
Angela Stefanachi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Selective, high affinity A2B adenosine receptor antagonists:: N-1 monosubstituted 8-(pyrazol-4-yl) xanthines
Rao V. Kalla et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
Caffeine and headaches
Robert E. Shapiro
CURRENT PAIN AND HEADACHE REPORTS (2008)
Discovery of a novel A2B adenosine receptor antagonist as a clinical candidate for chronic inflammatory airway diseases
Elfatih Elzein et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Does caffeine modulate verbal working memory processes? An fMRI study
F. Koppelstaetter et al.
NEUROIMAGE (2008)
Coffee consumption and mortality in a 14-year follow-up of an elderly northern Finnish population
Pertti Happonen et al.
BRITISH JOURNAL OF NUTRITION (2008)
Maternal caffeine intake during pregnancy and risk of fetal growth restriction: a large prospective observational study
Sinead Boylan et al.
BMJ-BRITISH MEDICAL JOURNAL (2008)
Prospective study of coffee consumption and risk of Parkinson's disease
K. Saaksjarvi et al.
EUROPEAN JOURNAL OF CLINICAL NUTRITION (2008)
Coffee consumption and risk of cardiovascular events after acute myocardial infarction - Results from the GISSI (Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico)-Prevenzione trial
Maria Giuseppina Silletta et al.
CIRCULATION (2007)
Caffeine analogs: biomedical impact
J. W. Daly
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Review article: Possible beneficial effects of coffee on liver disease and function
I. S. H. Cadden et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2007)
Coffee consumption is inversely associated with cognitive decline in elderly European men: the FINE Study
B. M. van Gelder et al.
EUROPEAN JOURNAL OF CLINICAL NUTRITION (2007)
Caffeinated beverage intake and the risk of heart disease mortality in the elderly: a prospective analysis
James A. Greenberg et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2007)
Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice
Oscar P. Dall'Igna et al.
EXPERIMENTAL NEUROLOGY (2007)
Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression
Xiulian Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Potent and orally bioavailable 8-bicyclo[2.2.2]octylxanthines as adenosine A1 receptor antagonists
William F. Kiesman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain β-amyloid production
G. W. Arendash et al.
NEUROSCIENCE (2006)
Coffee consumption and risk of total and cardiovascular mortality among patients with type 2 diabetes
S. Bidel et al.
DIABETOLOGIA (2006)
Sensitivity of glycogen phosphorylase isoforms to indole site inhibitors is markedly dependent on the activation state of the enzyme
S. Freeman et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Green tea consumption and mortality due to cardiovascular disease, cancer, and all causes in Japan - The Ohsaki Study
Shinichi Kuriyama et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)
New pyrrolopyrimidin-6-yl benzenesulfonamides:: Potent A2B adenosine receptor antagonists
Cristina Esteve et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Novel 1,3-disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) xanthines:: High affinity and selective A2B adenosine receptor antagonists
Rao V. Kalla et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Caffeine therapy for apnea of prematurity
B Schmidt et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies
SC Wilkinson et al.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH (2006)
Consumption of coffee is associated with reduced risk of death attributed to inflammatory and cardiovascular diseases in the Iowa Women's Health Study
Lene Frost Andersen et al.
AMERICAN JOURNAL OF CLINICAL NUTRITION (2006)
Coffee, caffeine, and risk of type 2 diabetes - A prospective cohort study in younger and middle-aged US women
RM van Dam et al.
DIABETES CARE (2006)
Direct block of human ether-a-go-go-related gene potassium channels by caffeine
SL Cockerill et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Coffee and health: A review of recent human research
JV Higdon et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2006)
Immunomodulatory effects of caffeine: Friend or foe?
Louise A. Horrigan et al.
PHARMACOLOGY & THERAPEUTICS (2006)
Habitual caffeine intake and the risk of hypertension in women
WC Winkelmayer et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)
Fatal caffeine overdose: Two case reports
S Kerrigan et al.
FORENSIC SCIENCE INTERNATIONAL (2005)
The fixed combination of acetylsalicylic acid, paracetamol and caffeine is more effective than single substances and dual combination for the treatment of headache: a multicentre, randomized, double-blind, single-dose, placebo-controlled parallel group study
HC Diener et al.
CEPHALALGIA (2005)
Methylated purines in urinary stones
K Safranow et al.
CLINICAL CHEMISTRY (2005)
New pyrrolo[2,1-f]purine-2,4-dione and imidazo[2,1-f]purine-2,4-dione derivatives as potent and selective human A3 adenosine receptor antagonists
PG Baraldi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Caffeine metabolism, genetics, and perinatal outcomes: A review of exposure assessment considerations during pregnancy
LM Grosso et al.
ANNALS OF EPIDEMIOLOGY (2005)
The next generation of phosphodiesterase inhibitors: Structural clues to ligand and substrate selectivity of phosphodiesterases
DT Manallack et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Optimization of purine based PDE1/PDE5 inhibitors to a potent and selective PDE5 inhibitor for the treatment of male ED
CD Boyle et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Dantrolene stabilizes domain interactions within the ryanodine receptor
S Kobayashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
2-Aryl-8-chloro-1,2,4-triazolo[1,5-a]quinoxalin-4-amines as highly potent A1 and A3 adenosine receptor antagonists
D Catarzi et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2005)
The discovery of a selective, high affinity A2B adenosine receptor antagonist for the potential treatment of asthma
J Zablocki et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Caffeine use in sports, pharmacokinetics in man, and cellular mechanisms of action
F Magkos et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2005)
Assessment of CYP1A2 activity in clinical practice: Why, how, and when?
MS Faber et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2005)
Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists
PG Baraldi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
More than the epidemiology of Alzheimer's disease: Contributions of the Canadian Study of Health and Aging
J Lindsay et al.
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE (2004)
A critical review of caffeine withdrawal: empirical validation of symptoms and signs, incidence, severity, and associated features
LM Juliano et al.
PSYCHOPHARMACOLOGY (2004)
Inhibition of phosphodiesterase 2 increases neuronal cGMP, synaptic plasticity and memory performance
FG Boess et al.
NEUROPHARMACOLOGY (2004)
The effects of habitual caffeine use on cognitive change: a longitudinal perspective
MPJ van Boxtel et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2003)
Modulation of presynaptic store calcium induces release of glutamate and postsynaptic firing
G Sharma et al.
NEURON (2003)
Caffeine analogs:: Effects on ryanodine-sensitive calcium-release channels and GABAA receptors
D Shi et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2003)
Neuroprotection by caffeine and adenosine A2A receptor blockade of β-amyloid neurotoxicity
OP Dall'lgna et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Caffeine, postmenopausal estrogen, and risk of Parkinson's disease
A Ascherio et al.
NEUROLOGY (2003)
8-(3-chlorostyryl)caffeine may attenuate MPTP neurotoxicity through dual actions of monoamine oxidase inhibition and A2A receptor antagonism
JF Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A meta-analysis of coffee drinking, cigarette smoking, and the risk of Parkinson's disease
MA Hernán et al.
ANNALS OF NEUROLOGY (2002)
Pyrido[2,1-f]purine-2,4-dione derivatives as a novel class of highly potent human A3 adenosine receptor antagonists
EM Priego et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Does caffeine intake protect from Alzheimer's disease?
L Maia et al.
EUROPEAN JOURNAL OF NEUROLOGY (2002)
1,8-disubstituted xanthine derivatives:: Synthesis of potent A2B-selective adenosine receptor antagonists
AM Hayallah et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Prospective study of caffeine consumption and risk of Parkinson's disease in men and women
A Ascherio et al.
ANNALS OF NEUROLOGY (2001)
Caffeine intake and the risk of first-trimester spontaneous abortion.
S Cnattingius et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)
Habitual caffeine consumption and its relation to memory, attention, planning capacity and psychomotor performance across multiple age groups
PAHM Hameleers et al.
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL (2000)
Clinically significant pharmacokinetic interactions between dietary caffeine and medications
JA Carrillo et al.
CLINICAL PHARMACOKINETICS (2000)
A new allosteric site in glycogen phosphorylase b as a target for drug interactions
NG Oikonomakos et al.
STRUCTURE (2000)
Association of coffee and caffeine intake with the risk of Parkinson disease
GW Ross et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)
Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A2B adenosine receptors
YC Kim et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)