Journal
JOURNAL OF MEDICAL VIROLOGY
Volume 93, Issue 10, Pages 6027-6029Publisher
WILEY
DOI: 10.1002/jmv.27109
Keywords
coronavirus; disease control; SARS coronavirus; vaccines; vaccine strains; virus classification
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Vaccination has become a major solution in the global pandemic of COVID-19, but it is important to remain vigilant for potential side effects and life-threatening complications. Anaphylactic cases post vaccination may have a recurrence of symptoms, highlighting the need for awareness. Recognizing the potential risk of anaphylaxis in select individuals and having appropriate measures in place to deal with adverse events is crucial.
In the setting of a coronavirus disease 2019 (COVID-19) global pandemic and increased disease burden, vaccination has become one of the major solutions. With the increase in vaccination numbers worldwide, it is important to stay vigilant to the potential side effects and life-threatening complications of such vaccines. We report the case of a 30-year-old male with a biphasic allergic reaction post messenger (mRNA) Pfizer-BioNTech COVID-19 vaccination. Several reports of allergic reactions have been cited in the literature after the administration of the mRNA Pfizer-BioNTech COVID-19 vaccine. It is important to keep a high index of suspicion in severe anaphylactic cases as some patients may have a recurrence of symptoms after discharge. It is crucial to acknowledge the potential risk of anaphylaxis in select individuals and have the appropriate measures in place to deal with adverse events. In case of severe symptoms, the administration of epinephrine is advised to prevent the development of a delayed biphasic anaphylactic reaction.
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