4.7 Editorial Material

Dupilumab: An Opportunity to Unravel In Vivo Actions of IL-4 and IL-13 in Humans

Journal

JOURNAL OF INVESTIGATIVE DERMATOLOGY
Volume 141, Issue 8, Pages 1879-1881

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.jid.2021.02.007

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In a new article, Bakker et al. (2021) demonstrate how dupilumab specifically targets skin-homing T cells, the key cells in atopic dermatitis, using deep immune cell phenotyping.
The application of biologics in clinical practice allows immunological observations under real-life conditions. In a new article in the Journal of Investigative Dermatology, Bakker et al. (2021) use deep immune cell phenotyping to demonstrate how dupilumab acts in a targeted fashion on skin-homing T cells, the driver cells of atopic dermatitis.

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