Journal
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Volume 142, Issue 3 PT B, Pages 867-875Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jid.2021.06.036
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Funding
- Case Western Reserve University School of Dental Medicine (Cleveland, OH) departmental startup funding
- Case Western Reserve University Skin Diseases Research Center pilot and feasibility grant - National Institute of Arthritis and Musculoskeletal and Skin Diseases (Bethesda, MD)
- National Institutes of Health (Bethesda, MD) (National Institute of Arthritis and Musculoskeletal and Skin Diseases) [P50AR070590]
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This review focuses on the IL-17A family of cytokines produced by T lymphocytes and other immune cells and their involvement in cutaneous pathogenic responses. It also discusses cutaneous dysbiosis and the role of FOXP3(+) regulatory T cells in inflammatory conditions linked to IL-17 responses in the skin. Specifically, it reviews key literature on chronic mucocutaneous candidiasis and psoriasis.
This review focuses on the IL-17A family of cytokines produced by T lymphocytes and other immune cells and how they are involved in cutaneous pathogenic responses. It will also discuss cutaneous dysbiosis and FOXP3(+) regulatory T cells in the context of inflammatory conditions linked to IL-17 responses in the skin. Specifically, it will review key literature on chronic mucocutaneous candidiasis and psoriasis.
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