Characteristics of Persons With Secondary Detection of Severe Acute Respiratory Syndrome Coronavirus 2 ≥90 days After First Detection, New Mexico 2020

Editorial Material Health Care Sciences & Services

Susceptibility of Southwestern American Indian Tribes to Coronavirus Disease 2019 (COVID-19)

Monika Kakol et al.

JOURNAL OF RURAL HEALTH (2021)

Article Immunology

Coronavirus Disease 2019 (COVID-19) Re-infection by a Phylogenetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Strain Confirmed by Whole Genome Sequencing

Kelvin Kai-Wang To et al.

Summary: The study confirmed reinfection in an apparently immunocompetent patient 142 days after the first symptomatic episode, rather than persistent viral shedding. This suggests that SARS-CoV-2 may continue to circulate among humans, even with natural herd immunity, highlighting the need for further research on protective immunological correlates for vaccine design.

CLINICAL INFECTIOUS DISEASES (2021)

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Article Infectious Diseases

Analysis of a persistent viral shedding patient infected with SARS-CoV-2 by RT-qPCR, FilmArray Respiratory Panel v2.1, and antigen detection

Yosuke Hirotsu et al.

Summary: Different diagnostic tests are being developed for detecting SARS-CoV-2, but discrepancies in results can occur, causing confusion. The study found that FilmArray RP v2.1 can detect SARS-CoV-2 with accuracy comparable to RT-qPCR, especially in early and intermediate phases of infection.

JOURNAL OF INFECTION AND CHEMOTHERAPY (2021)

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Article Medicine, General & Internal

SARS-CoV-2 persistence is associated with antigen-specific CD8 T-cell responses

Line K. Vibholm et al.

Summary: Persistent pharyngeal SARS-CoV-2 PCR positivity in post-symptomatic individuals may represent replicating virus, but is not contagious. Individuals with persistent PCR positivity demonstrate increased SARS-CoV-2-specific CD8 T-cell responses.

EBIOMEDICINE (2021)

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Article Medicine, General & Internal

Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study

Christian Holm Hansen et al.

Summary: The study investigated the protection against SARS-CoV-2 reinfection, with results showing an 80.5% protection rate for individuals previously infected. Even in the population aged 65 years and older, the protection rate against reinfection reached 47.1%, with no significant differences observed by gender or time since infection.

LANCET (2021)

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Article Public, Environmental & Occupational Health