4.5 Review

Research progress of the biosynthetic strains and pathways of bacterial cellulose

Journal

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/jimb/kuab071

Keywords

Bacterial cellulose; Biosynthesis; Cellulose synthase

Funding

  1. National Key R&D Program of China [2021YFC2100700]
  2. National Natural Science Foundation of China [21877053, 22008088]
  3. Jiangsu Planned Projects for Postdoctoral Research Funds [2020Z012]
  4. China Postdoctoral Science Foundation [2020M681485, 2021T140277]
  5. National first-class discipline program of Light Industry Technology and Engineering [LITE2018-24]
  6. Top-notch Academic Programs Project of Jiangsu Higher Education Institutions (TAPP)
  7. Fundamental Research Funds for the Central Universities [JUSRP11964]

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This review summarizes 30 cellulose-producing bacteria, discussing their physiological functions, metabolic synthesis mechanisms, and cellulose synthases, providing a reference for the exploration of new cellulose-producing microbes.
Bacterial cellulose is a glucose biopolymer produced by microorganisms and widely used as a natural renewable and sustainable resource in the world. However, few bacterial cellulose-producing strains and low yield of cellulose greatly limited the development of bacterial cellulose. In this review, we summarized the 30 cellulose-producing bacteria reported so far, including the physiological functions and the metabolic synthesis mechanism of bacterial cellulose, and the involved three kinds of cellulose synthases (type I, type II, and type III), which are expected to provide a reference for the exploration of new cellulose-producing microbes.

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