Resistant hypertension and COVID-19: tip of the iceberg?

Article Peripheral Vascular Disease

The effect of resistant hypertension on in-hospital mortality in patients hospitalized with COVID-19

Ferhat Isik et al.

Summary: Resistant hypertension is independently associated with increased in-hospital mortality in patients hospitalized with COVID-19, while no significant increased risk is observed with controlled hypertension. Additionally, age, gender, chronic renal failure, laboratory indices, and admission SpO2 levels are identified as independent predictors of in-hospital mortality in COVID-19 patients.

JOURNAL OF HUMAN HYPERTENSION (2022)

Add to Collection

Review Virology

The use of renin-angiotensin-aldosterone system (RAAS) inhibitors is associated with a lower risk of mortality in hypertensive COVID-19 patients: A systematic review and meta-analysis

Yixuan Wang et al.

Summary: Analysis of hypertensive COVID-19 patients treated with ACEI/ARB showed a lower risk of mortality and ventilatory support, with no significant impact of factors such as age, gender, study site, and comorbidities on the effectiveness of ACEI/ARB treatment.

JOURNAL OF MEDICAL VIROLOGY (2021)

Add to Collection

Article Cardiac & Cardiovascular Systems

Association between renin-angiotensin-aldosterone system inhibitor use and COVID-19 hospitalization and death: a 1.4 million patient nationwide registry analysis

Gianluigi Savarese et al.

Summary: In a nationwide cohort study in Sweden, the use of RAASi was not associated with an increased risk of hospitalization for or death from COVID-19.

EUROPEAN JOURNAL OF HEART FAILURE (2021)

Add to Collection

Article Peripheral Vascular Disease

Association Between Blood Pressure Control and Coronavirus Disease 2019 Outcomes in 45 418 Symptomatic Patients With Hypertension An Observational Cohort Study

James P. Sheppard et al.

Summary: This study found that patients with controlled blood pressure among those with hypertension had worse outcomes when infected with COVID-19, possibly due to more advanced atherosclerosis and target organ damage.

HYPERTENSION (2021)

Add to Collection

Article Peripheral Vascular Disease

Independent and combined effects of hypertension and diabetes on clinical outcomes in patients with COVID-19: A retrospective cohort study of Huoshen Mountain Hospital and Guanggu Fangcang Shelter Hospital

Yuhui Sun et al.

Summary: This study found that T2DM is a significant risk factor for death, ARDS/respiratory failure, and severe COVID-19 infection, while hypertension only presents additional risk for the development of severe infection. Hypertension is not an independent risk factor for death or ARDS/respiratory failure but marginally increases the risk of severe COVID-19 infection, accentuated through its confounding effect on T2DM.

JOURNAL OF CLINICAL HYPERTENSION (2021)

Add to Collection

Article Endocrinology & Metabolism

Body Mass Index and Risk of COVID-19 Diagnosis, Hospitalization, and Death: A Cohort Study of 2 524 926 Catalans

Martina Recalde et al.

Summary: The study revealed a positive association between BMI and the risks of COVID-19 diagnosis and hospitalization, while a J-shaped relationship with mortality was observed, particularly among younger patients. Further research is needed to understand the mechanisms underlying these relationships.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2021)

Add to Collection

Article Medicine, General & Internal