4.7 Review

T-cell receptor-based therapy: an innovative therapeutic approach for solid tumors

Related references

Note: Only part of the references are listed.
Review Genetics & Heredity

Genetic engineering of T cells for immunotherapy

Gavin I. Ellis et al.

Summary: Genetically engineered T cell immunotherapies have shown remarkable success in treating B cell acute lymphoblastic leukemia by using a patient's own T cells to target cancer cells. However, more complex levels of genetic regulation will be necessary to ensure safety and efficacy in future therapies.

NATURE REVIEWS GENETICS (2021)

Review Oncology

Promises and challenges of adoptive T-cell therapies for solid tumours

Matteo Morotti et al.

Summary: Cancer remains a leading cause of death globally, with metastatic disease posing challenges even with advancements in targeted therapies and immunotherapies. Adoptive T-cell therapy has shown promise in providing durable responses and potential cures for cancer patients. Advancements in genomics, immunology, and cell manufacturing are bringing personalized therapies for cancer patients closer to reality, challenging traditional standards of care and offering opportunities for a paradigm shift in cancer therapy.

BRITISH JOURNAL OF CANCER (2021)

Article Oncology

A CRISPR Screen Reveals Resistance Mechanisms to CD3-Bispecific Antibody Therapy

Si-Qi Liu et al.

Summary: The study revealed that deficiency in IFN-gamma signaling plays a key role in cancer resistance, and core fucosylation is a critical pathway to regulate the binding of CD3-bispecific antibodies to the CD123 antigen. These findings contribute to enhancing the clinical potential of current and future T-cell-engaging CD3-bispecific antibody therapies.

CANCER IMMUNOLOGY RESEARCH (2021)

Review Biotechnology & Applied Microbiology

Translating gammadelta (gamma delta) T cells and their receptors into cancer cell therapies

Zsolt Sebestyen et al.

NATURE REVIEWS DRUG DISCOVERY (2020)

Article Multidisciplinary Sciences

CRISPR-engineered T cells in patients with refractory cancer

Edward A. Stadtmauer et al.

SCIENCE (2020)

Article Biochemistry & Molecular Biology

T-cell receptor affinity in the age of cancer immunotherapy

Michele M. Hoffmann et al.

MOLECULAR CARCINOGENESIS (2020)

Article Medicine, General & Internal

KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma

Michael Wang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Review Pharmacology & Pharmacy

CRISPR/Cas systems to overcome challenges in developing the next generation of T cells for cancer therapy

Dennis Huang et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

Article Medicine, General & Internal

Overexpression of Mesothelin in Pancreatic Ductal Adenocarcinoma (PDAC)

Kai Le et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2020)

Article Biotechnology & Applied Microbiology

Facing the future: challenges and opportunities in adoptive T cell therapy in cancer

Isabelle Magalhaes et al.

EXPERT OPINION ON BIOLOGICAL THERAPY (2019)

Article Multidisciplinary Sciences

MAGE cancer-testis antigens protect the mammalian germline under environmental stress

Klementina Fon Tacer et al.

SCIENCE ADVANCES (2019)

Review Immunology

T cell receptor-based cancer immunotherapy: Emerging efficacy and pathways of resistance

Smita S. Chandran et al.

IMMUNOLOGICAL REVIEWS (2019)

Review Oncology

Tumor neoantigens: from basic research to clinical applications

Tao Jiang et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)

Article Oncology

MAGE-A1 in lung adenocarcinoma as a promising target of chimeric antigen receptor T cells

Yuan Mao et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)

Article Immunology

TCR Fingerprinting and Off-Target Peptide Identification

Armen R. Karapetyan et al.

FRONTIERS IN IMMUNOLOGY (2019)

Article Oncology

Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma

Indu Ramachandran et al.

JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)

Article Hematology

ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells

Daniel W. Lee et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2019)

Article Medicine, General & Internal

Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Stephen J. Schuster et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Review Medicine, General & Internal

Chimeric Antigen Receptor Therapy

Carl H. June et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

S. L. Maude et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Review Immunology

Engineering Approaches in Human Gamma Delta T Cells for Cancer Immunotherapy

Jonathan Fisher et al.

FRONTIERS IN IMMUNOLOGY (2018)

Article Medicine, Research & Experimental

Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation

Sonia Guedan et al.

JCI INSIGHT (2018)

Article Oncology

NY-ESO-1 expression predicts an aggressive phenotype of ovarian cancer

J. Brian Szender et al.

GYNECOLOGIC ONCOLOGY (2017)

Review Biotechnology & Applied Microbiology

Engineering Natural Killer Cells for Cancer Immunotherapy

Katayoun Rezvani et al.

MOLECULAR THERAPY (2017)

Review Multidisciplinary Sciences

Therapeutic T cell engineering

Michel Sadelain et al.

NATURE (2017)

Article Medicine, General & Internal

Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas

Stephen J. Schuster et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

S. S. Neelapu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Oncology

Targeting neoantigens to augment antitumour immunity

Mark Yarchoan et al.

NATURE REVIEWS CANCER (2017)

Article Multidisciplinary Sciences

Mesothelin as a biomarker for ovarian carcinoma: a meta-analysis

Kristian Madeira et al.

ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2016)

Review Immunology

The urgent need to recover MHC class I in cancers for effective immunotherapy

Federico Garrido et al.

CURRENT OPINION IN IMMUNOLOGY (2016)

Article Medicine, Research & Experimental

Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia

Paulina J. Paszkiewicz et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Review Immunology

TCR-engineered T cells to treat tumors: Seeing but not touching?

Reno Debets et al.

SEMINARS IN IMMUNOLOGY (2016)

Review Pharmacology & Pharmacy

Adoptive T Cell Therapies: A Comparison of T Cell Receptors and Chimeric Antigen Receptors

Daniel T. Harris et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2016)

Article Biochemistry & Molecular Biology

NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma

Aaron P. Rapoport et al.

NATURE MEDICINE (2015)

Review Multidisciplinary Sciences

Adoptive cell transfer as personalized immunotherapy for human cancer

Steven A. Rosenberg et al.

SCIENCE (2015)

Review Multidisciplinary Sciences

Neoantigens in cancer immunotherapy

Ton N. Schumacher et al.

SCIENCE (2015)

Review Immunology

T cell metabolic fitness in antitumor immunity

Peter J. Siska et al.

TRENDS IN IMMUNOLOGY (2015)

Review Immunology

γδ T Cells: First Line of Defense and Beyond

Yueh-hsiu Chien et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)

Review Cell & Tissue Engineering

Opportunities and limitations of natural killer cells as adoptive therapy for malignant disease

James O. J. Davies et al.

CYTOTHERAPY (2014)

Review Immunology

Re-adapting T cells for cancer therapy: from mouse models to clinical trials

Ingunn M. Stromnes et al.

IMMUNOLOGICAL REVIEWS (2014)

Review Immunology

TCR repertoires of intratumoral T-cell subsets

Carsten Linnemann et al.

IMMUNOLOGICAL REVIEWS (2014)

Article Medicine, General & Internal

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

Shannon L. Maude et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Multidisciplinary Sciences

Molecular architecture of the αβ T cell receptor-CD3 complex

Michael E. Birnbaum et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Editorial Material Medicine, Research & Experimental

Elevated PRAME expression: what does this mean for treatment of head and neck squamous cell carcinoma?

Miroslaw J. Szczepanski et al.

BIOMARKERS IN MEDICINE (2013)

Article Biochemistry & Molecular Biology

Expression and prognostic relevance of PRAME in primary osteosarcoma

Pingxian Tan et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

Review Biotechnology & Applied Microbiology

Challenges in T cell receptor gene therapy

Benjamin J. Uttenthal et al.

JOURNAL OF GENE MEDICINE (2012)

Review Oncology

The blockade of immune checkpoints in cancer immunotherapy

Drew M. Pardoll

NATURE REVIEWS CANCER (2012)

Article Immunology

Contribution of IL-17-producing γδ T cells to the efficacy of anticancer chemotherapy

Yuting Ma et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2011)

Review Multidisciplinary Sciences

The Polycomb complex PRC2 and its mark in life

Raphael Margueron et al.

NATURE (2011)

Review Immunology

Mechanisms for T cell receptor triggering

P. Anton van der Merwe et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Review Immunology

Towards a systems understanding of MHC class I and MHC class II antigen presentation

Jacques Neefjes et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Article Biochemistry & Molecular Biology

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

Jennifer M. Doyle et al.

MOLECULAR CELL (2010)

Article Biochemistry & Molecular Biology

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy

Gavin M. Bendle et al.

NATURE MEDICINE (2010)

Article Oncology

High frequency of MAGE-A4 and MAGE-A9 expression in high-risk bladder cancer

Alain Bergeron et al.

INTERNATIONAL JOURNAL OF CANCER (2009)

Review Hematology

B lymphocytes: how they develop and function

Tucker W. LeBien et al.

BLOOD (2008)

Article Multidisciplinary Sciences

Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity

Douglas C. Palmer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming

Djordje Atanackovic et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Review Oncology

Increased intensity lymphodepletion and adoptive immunotherapy - how far can we go?

Pawel Muranski et al.

NATURE CLINICAL PRACTICE ONCOLOGY (2006)

Article Multidisciplinary Sciences

Cancer regression in patients after transfer of genetically engineered lymphocytes

Richard A. Morgan et al.

SCIENCE (2006)

Review Oncology

Cancer/testis antigens, gametogenesis and cancer

AJG Simpson et al.

NATURE REVIEWS CANCER (2005)

Article Medicine, General & Internal

Epidemiologic classification of human papillomavirus types associated with cervical cancer

N Muñoz et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)

Article Oncology

Evidence for a causal association between human papillomavirus and a subset of head and neck cancers

ML Gillison et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)