Journal
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
Volume 34, Issue 4, Pages 280-288Publisher
SAGE PUBLICATIONS INC
DOI: 10.1177/08919887211018267
Keywords
Parkinson's disease; depression; anxiety; bipolar disorder; mood disorders
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Mood disorders and anxiety significantly impact the prognosis and disease course of Parkinson's disease, with overlapping symptoms making accurate diagnosis difficult. Treatment options for these conditions can lead to motor complications and reduced quality of life for patients.
Mood disorders and anxiety significantly impact the prognosis and disease course of Parkinson's disease. Non-motor symptoms of Parkinson's disease such as apathy, anhedonia, and fatigue overlap with diagnostic criteria for anxiety and depression, thus making accurate diagnosis of mood disorders in Parkinson's disease patients difficult. Furthermore, treatment options for mood disorders can produce motor complications leading to poor adherence and impaired quality of life in Parkinson's disease patients. This review aims to clarify the current state of diagnostic and treatment options pertaining to anxiety and mood disorders in Parkinson's disease. It explores both the pharmacologic and non-pharmacologic treatment modalities for various mood disorders in comorbid Parkinson's disease with a brief discussion of the future outlook of the field given the current state of the literature.
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