Related references
Note: Only part of the references are listed.GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility
Daniel Eriksson et al.
NATURE COMMUNICATIONS (2021)
Dual functions of Aire CARD multimerization in the transcriptional regulation of T cell tolerance
Yu-San Huoh et al.
NATURE COMMUNICATIONS (2020)
UTAP: User-friendly Transcriptome Analysis Pipeline
Refael Kohen et al.
BMC BIOINFORMATICS (2019)
The ENCODE Blacklist: Identification of Problematic Regions of the Genome
Haley M. Amemiya et al.
SCIENTIFIC REPORTS (2019)
Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus
Jennifer E. Cowan et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2018)
Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE)
Jordan K. Abbott et al.
JOURNAL OF AUTOIMMUNITY (2018)
Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy-like Autoimmune Disease
Jason Ossart et al.
JOURNAL OF IMMUNOLOGY (2018)
Rapid chromatin repression by Aire provides precise control of immune tolerance
Andrew S. Koh et al.
NATURE IMMUNOLOGY (2018)
Autoimmune Polyendocrine Syndromes
Eystein S. Husebye et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Transcriptional programs that control expression of the autoimmune regulator gene Aire
Yonatan Herzig et al.
NATURE IMMUNOLOGY (2017)
PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX
Erwan Delbarre et al.
GENOME RESEARCH (2017)
The transcriptional regulator Aire binds to and activates super-enhancers
Kushagra Bansal et al.
NATURE IMMUNOLOGY (2017)
deepTools2: a next generation web server for deep-sequencing data analysis
Fidel Ramirez et al.
NUCLEIC ACIDS RESEARCH (2016)
A highly conserved NF-κB-responsive enhancer is critical for thymic expression of Aire in mice
Uku Haljasorg et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2015)
Gastrointestinal Autoimmunity Associated With Loss of Central Tolerance to Enteric α-Defensins
Jan Dobes et al.
GASTROENTEROLOGY (2015)
Dominant Mutations in the Autoimmune Regulator AIRE Are Associated with Common Organ-Specific Autoimmune Diseases
Bergithe E. Oftedal et al.
IMMUNITY (2015)
Identification of a novel cis-regulatory element essential for immune tolerance
Taylor N. LaFlam et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2015)
Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells
Charles St-Pierre et al.
JOURNAL OF IMMUNOLOGY (2015)
The Phyre2 web portal for protein modeling, prediction and analysis
Lawrence A. Kelley et al.
NATURE PROTOCOLS (2015)
Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance
Siyoung Yang et al.
SCIENCE (2015)
ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases
Li Shen et al.
BMC GENOMICS (2014)
Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia
Stephen N. Sansom et al.
GENOME RESEARCH (2014)
Shaping the repertoire of tumor-infiltrating effector and regulatory T cells
Peter A. Savage et al.
IMMUNOLOGICAL REVIEWS (2014)
Chromatin state dynamics during blood formation
David Lara-Astiaso et al.
SCIENCE (2014)
Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types
Diego Adhemar Jaitin et al.
SCIENCE (2014)
Serotonin paracrine signaling in tissue fibrosis
Derek A. Mann et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states
Ronnie Blecher-Gonen et al.
NATURE PROTOCOLS (2013)
Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance
Siyoung Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
The Autoimmune Regulator Prevents Premature Reproductive Senescence in Female Mice
Susmita Jasti et al.
BIOLOGY OF REPRODUCTION (2012)
Loss of Enteroendocrine Cells in Autoimmune-Polyendocrine-Candidiasis-Ectodermal-Dystrophy (APECED) Syndrome with Gastrointestinal Dysfunction
C. Posovszky et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2012)
Fast gapped-read alignment with Bowtie 2
Ben Langmead et al.
NATURE METHODS (2012)
AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome
Massimiliano Gaetani et al.
NUCLEIC ACIDS RESEARCH (2012)
Classification and functions of enteroendocrine cells of the lower gastrointestinal tract
Ashok R. Gunawardene et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2011)
The susceptibility of Aire-/- mice to experimental myasthenia gravis involves alterations in regulatory T cells
Revital Aricha et al.
JOURNAL OF AUTOIMMUNITY (2011)
Integrative genomics viewer
James T. Robinson et al.
NATURE BIOTECHNOLOGY (2011)
Transcriptional Autoregulation by BRCA1
Adriana De Siervi et al.
CANCER RESEARCH (2010)
Three-dimensional organization of promyelocytic leukemia nuclear bodies
Marion Lang et al.
JOURNAL OF CELL SCIENCE (2010)
Aire-Deficient C57BL/6 Mice Mimicking the Common Human 13-Base Pair Deletion Mutation Present with Only a Mild Autoimmune Phenotype
Francois-Xavier Hubert et al.
JOURNAL OF IMMUNOLOGY (2009)
Radioimmunoassay for autoantibodies against interferon omega;: its use in the diagnosis of autoimmune polyendocrine syndrome type I
Bergithe E. Oftedal et al.
CLINICAL IMMUNOLOGY (2008)
The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression
Tonis Org et al.
EMBO REPORTS (2008)
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire
Maureen A. Su et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Autoimmune polyendocrine syndrome type 1 and NALP5, parathyroid autoantigen
Mohammad Alimohammadi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2008)
Transcriptional Autoregulatory Loops Are Highly Conserved in Vertebrate Evolution
Szymon M. Kielbasa et al.
PLOS ONE (2008)
Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity
Andrew S. Koh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Deletional tolerance mediated by extrathymic Aire-expressing cells
James M. Gardner et al.
SCIENCE (2008)
Model-based Analysis of ChIP-Seq (MACS)
Yong Zhang et al.
GENOME BIOLOGY (2008)
Review: Enteroendocrine cells: Neglected players in gastrointestinal disorders?
Gordon W. Moran et al.
Therapeutic Advances in Gastroenterology (2008)
AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity
Brian J. Ferguson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
Katharina Aschenbrenner et al.
NATURE IMMUNOLOGY (2007)
Autoimmune polyendocrine syndrome type 1 in Norway: Phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene
Anette S. B. Wolff et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal
Guangjin Pan et al.
FASEB JOURNAL (2006)
PML nuclear bodies are highly organised DNA-protein structures with a function in heterochromatin remodelling at the G2 phase
Judith J. Luciani et al.
JOURNAL OF CELL SCIENCE (2006)
Modifier loci condition autoimmunity provoked by Aire deficiency
WY Jiang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity
H Grasberger et al.
MOLECULAR ENDOCRINOLOGY (2005)
NMR structure of the first PHD finger of autoimmune regulator protein (AIRE1)
MJ Bottomley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Chromatin contributes to structural integrity of promyelocytic leukemia bodies through a SUMO-1-independent mechanism
CH Eskiw et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
APECED-causing mutations in AIRE reveal the functional domains of the protein
M Halonen et al.
HUMAN MUTATION (2004)
Establishment of the acute myeloid leukemia cell line Kasumi-6 from a patient with a dominant-negative mutation in the DNA-binding region of the C/EBPα gene
H Asou et al.
GENES CHROMOSOMES & CANCER (2003)
Systematic mutagenesis of the functional domains of AIRE reveals their role in intracellular targeting
C Ramsey et al.
HUMAN MOLECULAR GENETICS (2002)
Projection of an immunological self shadow within the thymus by the aire protein
MS Anderson et al.
SCIENCE (2002)
Negative autoregulation speeds the response times of transcription networks
N Rosenfeld et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
C Ramsey et al.
HUMAN MOLECULAR GENETICS (2002)
The autoimmune regulator (AIRE) is a DNA-binding protein
PG Kumar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB
RJ Barndt et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
RM Siegel et al.
SCIENCE (2000)
Mutations in the AIRE gene:: Effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein
P Björses et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2000)
Share Paper
