Journal
JOURNAL OF EMERGENCY MEDICINE
Volume 61, Issue 6, Pages E141-E145Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jemermed.2021.07.062
Keywords
Guillain-Barre Syndrome (GBS); facial diplegia; CN-VII palsy; COVID-19 vaccination; dysarthria
Categories
Ask authors/readers for more resources
Guillain-Barre Syndrome, a rapidly progressive immune-mediated polyneuropathy often related to infectious illnesses or vaccinations, can present with varied symptoms and may lead to life-threatening complications like respiratory failure. Early recognition and treatment of GBS by physicians, especially during the COVID-19 pandemic vaccination campaign, is crucial for patient outcomes.
Background: Guillain-BarreSyndrome (GBS) is a rapidly progressive immune-mediated polyneuropathy often associated with an antecedent infectious illness or vaccination. The classic presentation of GBS is characterized by ascending limb weakness and numbness with loss of reflexes. However, atypical variants involving the face and arms or with purely sensory symptoms also exist. In up to 30% of cases, GBS progresses to respiratory failure, with patients requiring mechanical ventilation. Case Report : We report a case of atypical GBS occurring after Coronavirus disease 2019 (COVID-19) vaccination in an otherwise healthy 38-year-old man. The patient's clinical presentation was characterized by bilateral hand and foot paresthesias, dysarthria, bilateral facial weakness, and an absence of classic ascending limb weakness. Albuminocytological dissociation within the cerebrospinal fluid was suggestive of GBS. The patient received intravenous immunoglobulin therapy, with modest improvement in his symptoms at the time of his discharge from the hospital. Why Should an Emergency Physician Be Aware of This? Patients with GBS are at risk for life-threatening complications, including respiratory failure requiring mechanical ventilation. It is critical for emergency physicians to be aware of the manifold presentations of GBS for early recognition and treatment. This may be of particular importance in the context of a worldwide vaccination campaign in response to the COVID-19 pandemic. (C) 2021 Elsevier Inc. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available