Journal
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
Volume 63, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.jddst.2021.102539
Keywords
Nanotechnology; Cancer; Drug delivery; Pancreatic cancer; Therapy; Nanoparticles
Categories
Funding
- Deanship of Scientific Research at King Khalid University, Saudi Arabia [R.G.P. 168-42]
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Pancreatic cancer is a highly lethal disease that requires increased attention and research. Nanotechnology offers new hope for improving the effectiveness of treatments and targeting specific agents. Future developments may lead to advanced multifunctional nanostructures for detection and therapy of pancreatic cancer.
Pancreatic cancer kills countless people every year throughout the globe and persists as one of the extremely lethal diseases that need foremost attention because the overall endurance percentage of pancreatic cancer is very little. Early diagnosis and efficient treatments are two of the biggest hurdles in the fight towards cancer. In the present work, we have reviewed thriving strategies concerning the pancreatic cancer therapy and thoroughly described the most recent developments in emerging modern drug delivery systems focused on and derived from nanotechnology. Recent advances in nanotechnology-based drug delivery systems have aimed to boost cellular uptake, improve pharmacokinetics and effectiveness of anti-cancer drugs, which consequently have assisted in potent attacking of specific agents for effectual pancreatic cancer therapy. Present review furnishes an insight into current progresses on potential curative targets for pancreatic cancer treatment. This knowledge might be useful as a basis for the potential development of multi-functional nano-constructions for advanced detection of pancreatic cancer as well as its efficient therapy.
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