Preparation of a novel, efficient, and recyclable magnetic catalyst, Cu(II)-OHPC-Fe3O4 nanoparticles, and a solvent-free protocol for the synthesis of coumarin derivatives

Cu(II) supported on 5-oxo-4,5-dihydro-pyrrole-3-carboxylic acid functionalized Fe3O4 nanoparticles (Cu(II)-OHPC-Fe3O4) as a new magnetic nanocatalyst was prepared and characterized by ICP-AES, FT-IR, XRD, SEM, TEM, TGA, XRD, VSM and EDX techniques. Prepared nanocatalyst (Cu(II)-OHPC-Fe3O4) is employed for Pechmann reactions between different substituted phenols and ethyl acetoacetate to obtain new products of coumarin derivatives in good to excellent yields. This green catalyst was easily removed, reused several times with no significant loss of its activity and provided clean synthesis with excellent yield and reduced time.

Automated summary

A new magnetic nanocatalyst, Cu(II)-OHPC-Fe3O4, was prepared by supporting Cu(II) on functionalized Fe3O4 nanoparticles and used for the synthesis of coumarin derivatives with high yields and excellent reusability. This green catalyst provides clean synthesis, reduced reaction time, and minimal loss of activity upon multiple reuses.