Journal
FOOD CHEMISTRY
Volume 194, Issue -, Pages 857-863Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2015.08.091
Keywords
Strawberry; Phenolic compounds; Structure determination; Antioxidant activity; alpha-Glucosidase inhibitory activity
Funding
- National Basic Research Program of China [2013CB127106]
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Three new phenolic glucosides, falandiosides A (1), B (2), and C (6) were isolated from strawberry (Fragaria x ananassa Duch.) cv. Falandi fruit, together with three flavone glucuronides (3-5), eleven lignan glycosides (12-22), and five others. Their structures were determined by spectroscopic methods. All the known phenolics were reported from strawberry for the first time. They were evaluated for antioxidant and alpha-glucosidase inhibitory activities. Three new and fifteen known phenolics showed potent 2,2'-azinobis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical cation scavenging activity with IC50 values of 22.50-4.28 mu M in comparison to L-ascorbic acid (14.21 mu M). Quercetin 3-(6-methylglucuronide) (4), (+)-isolariciresinol 9'-glucoside (12), and (-)-isolariciresinol 9'-glucoside (13) were active in scavenging 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Moreover, compounds 12 and 13 had moderate ferric reducing antioxidant power (FRAP) values. Further, two new and seven known phenolics exhibited more potent alpha-glucosidase inhibitory activity with IC50 values of 537.43-25.39 mu M than acarbose (619.94 mu M). (C) 2015 Elsevier Ltd. All rights reserved.
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