Exploration of Interactions between Pyridoxine HCl (Vitamin B6) and {Hexadecyltrimethylammonium Bromide plus Sodium Cholate (Trihydroxy Bile Salt)} Mixtures at T = (298.15 to 318.15) K: Physicochemical and Spectroscopic Approach

Studies on the interactions of surfactant molecules with water-soluble vitamins have significance in pharmaceutical, biological, and industrial processes. Their mixed micelles can be used as a model for understanding the complex behavior encountered in food and biological assemblies. In this context, self-assembling properties of hexadecyltrimethylammonium bromide, HTAB, and sodium cholate, NaC, and their mixtures at molar fractions, alpha(HTAB) = (0.02, 0.04, and 0.13), have been investigated in water as well as in (1, 2, and 3) x 10(-4) mol.kg(-1) pyridoxine HCl(aq) (vitamin B-6) solutions by employing various techniques. Critical micelle concentration, degree of ionization (g), and standard thermodynamic entities (Delta G(m)(0), Delta H-m(0), and Delta S-m(0)) of micellization which state the physicochemical properties of the studied system have been determined from the conductivity measurements at 298.15, 308.15, and 318.15 K. The partial specific volume (phi(v)), isentropic compressibility (kappa(s)), and partial specific isentropic compressibility (phi(kappa)) were evaluated using the density and sound velocity data. UV-visible absorption and fluorescence emission spectra were recorded for pyridoxine HCl( aq) solutions in the presence of HTAB and NaC and mixed (HTAB + NaC) surfactants at alpha(HTAB) = (0.02, 0.04, and 0.13) and at T = 298.15 K. Through dynamic light scattering studies, the hydrodynamic diameters (D-h) of aggregates have been examined.

Automated summary

The study on the interactions of surfactant molecules with water-soluble vitamins is significant in pharmaceutical, biological, and industrial processes. By investigating the self-assembling properties and physicochemical properties of these systems in aqueous solutions, this research provides insights into the complex behavior encountered in food and biological assemblies. Through various techniques, critical micelle concentration, degree of ionization, and thermodynamic entities of micellization have been determined, and UV-visible absorption and fluorescence emission spectra have been recorded to further study the behavior of these mixtures.