Journal
JOURNAL OF CELL BIOLOGY
Volume 220, Issue 9, Pages -Publisher
ROCKEFELLER UNIV PRESS
DOI: 10.1083/jcb.202106128
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Funding
- Canadian Cancer Society (Canadian Cancer Society Research Institute) [Impact 704116]
- Canadian Institutes of Health Research [FDN 143277]
- Terry Fox Research Institute
- Agence Nationale de la Recherche (AMBRE Project) [ANR-17CE13-0011]
- Ligue Contre le Cancer (Programme equipe Labellisee)
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Aurora A is a key kinase involved in regulating mitotic processes. Recent studies have identified multiple mechanisms of Aurora A activation, each occurring at specific subcellular locations and regulated by signaling events.
Aurora A is a serine/threonine kinase essential for mitotic entry and spindle assembly. Recent molecular studies have revealed the existence of multiple, distinct mechanisms of Aurora A activation, each occurring at specific subcellular locations, optimized for cellular context, and primed by signaling events including phosphorylation and oxidation.
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