4.7 Article

Translational regulation in the brain by TDP-43 phase separation

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

TDP-43 α-helical structure tunes liquid-liquid phase separation and function

Alexander E. Conicella et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Biochemistry & Molecular Biology

The molecular language of membraneless organelles

Edward Gomes et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2019)

Article Neurosciences

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

Jacob R. Mann et al.

NEURON (2019)

Article Multidisciplinary Sciences

Phase separation-deficient TDP43 remains functional in splicing

Hermann Broder Schmidt et al.

NATURE COMMUNICATIONS (2019)

Article Biochemistry & Molecular Biology

The physical forces mediating self-association and phase-separation in the C-terminal domain of TDP-43

Hao-Ru Li et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2018)

Article Biochemistry & Molecular Biology

A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing

Ailin Wang et al.

EMBO JOURNAL (2018)

Article Biochemistry & Molecular Biology

Tau protein liquid-liquid phase separation can initiate tau aggregation

Susanne Wegmann et al.

EMBO JOURNAL (2018)

Article Biochemistry & Molecular Biology

TAR DNA-binding protein 43 (TDP-43) liquid-liquid phase separation is mediated by just a few aromatic residues

Hao-Ru Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Review Biochemistry & Molecular Biology

Who's In and Who's Out-Compositional Control of Biomolecular Condensates

Jonathon A. Ditlev et al.

JOURNAL OF MOLECULAR BIOLOGY (2018)

Review Biochemistry & Molecular Biology

Methods for Physical Characterization of Phase-Separated Bodies and Membrane-less Organelles

Diana M. Mitrea et al.

JOURNAL OF MOLECULAR BIOLOGY (2018)

Editorial Material Multidisciplinary Sciences

Translation dysregulation in neurodegenerative disorders

Daryl A. Bosco

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Neurosciences

Tdp-43 cryptic exons are highly variable between cell types

Yun Ha Jeong et al.

MOLECULAR NEURODEGENERATION (2017)

Article Genetics & Heredity

Quantitative analysis of cryptic splicing associated with TDP-43 depletion

Jack Humphrey et al.

BMC MEDICAL GENOMICS (2017)

Article Biochemistry & Molecular Biology

Dynamics of Translation of Single mRNA Molecules In Vivo

Xiaowei Yan et al.

Article Biochemical Research Methods

The Perseus computational platform for comprehensive analysis of (prote)omics data

Stefka Tyanova et al.

NATURE METHODS (2016)

Article Cell Biology

In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes

Hermann Broder Schmidt et al.

CELL REPORTS (2016)

Article Multidisciplinary Sciences

TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD

Jonathan P. Ling et al.

SCIENCE (2015)

Article Cell Biology

Place Cells, Grid Cells, and Memory

May-Britt Moser et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)

Article Biochemistry & Molecular Biology

MFN2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons

Wenzhang Wang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Review Cell Biology

Liquid-Liquid Phase Separation in Biology

Anthony A. Hyman et al.

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30 (2014)

Article Biochemistry & Molecular Biology

A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging

Marvin E. Tanenbaum et al.

Review Clinical Neurology

Frontotemporal dementia: diagnosis, deficits and management

Nicholas T. Bott et al.

NEURODEGENERATIVE DISEASE MANAGEMENT (2014)

Article Biotechnology & Applied Microbiology

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Michael I. Love et al.

GENOME BIOLOGY (2014)

Article Biochemical Research Methods

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran et al.

NATURE PROTOCOLS (2013)

Article Medicine, Research & Experimental

Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

Lionel M. Igaz et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Biochemical Research Methods

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

Juergen Cox et al.

JOURNAL OF PROTEOME RESEARCH (2011)

Review Genetics & Heredity

Synonymous but not the same: the causes and consequences of codon bias

Joshua B. Plotkin et al.

NATURE REVIEWS GENETICS (2011)

Article Clinical Neurology

Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis

Brian C. Kraemer et al.

ACTA NEUROPATHOLOGICA (2010)

Article Biochemistry & Molecular Biology

TDP-43 Is a Developmentally Regulated Protein Essential for Early Embryonic Development

Chantelle F. Sephton et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Multidisciplinary Sciences

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

Hans Wils et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Biochemical Research Methods

Streptomyces erythraeus Trypsin for Proteomics Applications

Jianying Z. Kiser et al.

JOURNAL OF PROTEOME RESEARCH (2009)

Article Biochemical Research Methods

In-gel digestion for mass spectrometric characterization of proteins and proteomes

Andrej Shevchenko et al.

NATURE PROTOCOLS (2006)

Article Multidisciplinary Sciences

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

A Subramanian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Behavioral Sciences

Hippocampal lesions, species-typical behaviours and anxiety in mice

RMJ Deacon et al.

BEHAVIOURAL BRAIN RESEARCH (2005)