Silk sericin/fibroin electrospinning dressings: a method for preparing a dressing material with high moisture vapor transmission rate

The current study focuses on the preparation of sericin and silk fibroin blend electrostatic spinning fiber film dressing. The surface morphology of the fiber films was observed by scanning electron microscope, and the hydrophilicity and swelling property of the fiber membrane dressing were analyzed. The biocompatibility of the four dressings was verified by the CCK-8 method and confocal laser microscopy. This experiment showed that the dressing group with the ratio of sericin to silk fibroin of 3:7 had better performance, offering fine and uniform fiber structure, good surface hydrophilicity, high water vapor transmission rate. The swelling rate of it was 822.77 +/- 62.78%, and the tensile properties reached the requirements of dressing materials and had an excellent ability to promote cell adhesion and proliferation. This paper provides a possible method for producing of dressing materials with good hydrophilicity and high moisture vapor transmission rate.

Automated summary

This study successfully prepared a sericin and silk fibroin blend electrostatic spinning fiber film dressing, with the dressing group at a ratio of 3:7 showing the best performance. It exhibited fine fiber structure, good hydrophilicity, high water vapor transmission rate, and excellent ability to promote cell adhesion and proliferation, providing a possible method for producing dressing materials with good hydrophilicity and high moisture vapor transmission rate.