4.7 Review

Air pollution and lung function in children

Journal

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Volume 148, Issue 1, Pages 1-14

Publisher

MOSBY-ELSEVIER
DOI: 10.1016/j.jaci.2021.05.006

Keywords

Children; lung function; FEV1; FVC; air pollution; wildfire; gas stoves; biomass

Funding

  1. National Institute of Environmental Health Sciences [P30 ES00002, P30 ES007048]

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This narrative review summarizes the impact of air pollution on child lung function and growth, including both short-term and long-term exposures to different types of air pollutants and improvements in exposure assessment tools. The review points out research gaps and highlights areas needing further investigation.
In this narrative review, we summarize the literature and provide updates on recent studies of air pollution exposures and child lung function and lung function growth. We include exposures to outdoor air pollutants that are monitored and regulated through air quality standards, and air pollutants that are not routinely monitored or directly regulated, including wildfires, indoor biomass and coal burning, gas and wood stove use, and volatile organic compounds. Included is a more systematic review of the recent literature on long-term air pollution and child lung function because this is an indicator of future adult respiratory health and exposure assessment tools have improved dramatically in recent years. We present summary observations and knowledge gaps. We end by discussing what is known about what can be done at the individual/household, local/regional, and national levels to overcome structural impediments, reduce air pollution exposures, and improve child lung function. We found a large literature on adverse air pollution effects on children's lung function level and growth; however, many questions remain. Important areas needing further research include whether early-life effects are fixed or reversible; and what are windows of increased susceptibility, long-term effects of repeated wildfire events, and effects of air quality interventions.

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