Quartz-Wool-Supported Surface Dummy Molecularly Imprinted Silica as a Novel Solid-Phase Extraction Sorbent for Determination of Bisphenol A in Water Samples and Orange Juice

A type of quartz wool-supported surface dummy molecularly imprinted silica (QW@MIP) was prepared using bisphenol AF as the template molecule for solid-phase extraction of bisphenol A (BPA). The QW@MIP was characterized by FT-IR spectroscopy, scanning electron microscopy, and thermo-gravimetric analysis. The adsorption tests showed that the QW@MIP had high-adsorption ability and a fast binding kinetics for BPA. When used as a solid-phase extraction (SPE) sorbent for BPA, the QW@MIP showed ease of packing SPE cartridge, low flow resistance, high extraction efficiency, high enrichment factor, and good reusability. Moreover, the dummy-imprinting technique used herein can effectively avoid the interference of residual template molecules in sorbent to determination of BPA. A new SPE method was developed using the QW@MIP sorbent, and then coupled with a high-performance liquid chromatography method, it was successfully applied to the detection of BPA spiked in water samples and orange juice and that in a certified sample with recoveries of 96.7-103.1% (RSD = 1.0-2.8%), 96.9-99.9% (RSD = 1.0-2.9%), and 99.2% (RSD = 0.5%), respectively. The limit of detection (S/N = 3) and limit of quantification (S/N = 10) for all samples were 0.05 and 0.17 ng mL(-1), respectively. The QW@MIP can be potentially used as a good SPE sorbent for BPA in environmental water samples and beverages.