Recent advances of oral film as platform for drug delivery

Orally drug delivery film has received extensive interest duo to a distinct set of its advantageous properties compared to the traditional orally administered dosages, including faster rate of drug absorption, higher bioavailability and better patient compliance for children and elders with swallowing deficiencies. In particular, its potential capacity of delivering proteins and peptides has further attracted great attention. Lately, tremendous advances have been made in designing and developing both novel mucoadhesive films and orodispersible films to fulfill specific accomplishments of drug delivery. This review aims to summarize those newly developed oral films, discussing their formulation strategies, manufacturing methods as well as advantages and limitations thereof. Conclusions and future perspectives are also provided in brief.

Automated summary

Orally drug delivery films have attracted extensive interest due to their faster rate of drug absorption, higher bioavailability, and better patient compliance, especially for children and elders with swallowing difficulties. Recent advances in designing and developing novel oral films have focused on delivering proteins and peptides effectively. This review aims to summarize these newly developed oral films, discussing their formulation strategies, manufacturing methods, advantages, and limitations.