4.7 Review

The Role of Mutant p63 in Female Fertility

Related references

Note: Only part of the references are listed.
Review Pathology

Endometriosis: A Comprehensive Review

Maria Arafah et al.

Summary: Endometriosis is a common condition where endometrial tissue develops outside the uterus, leading to chronic pain and infertility. The pathogenesis is multifactorial and may involve various theories, with pelvic organs typically affected but potentially extending to distant locations in the body. Treatment focuses on managing symptoms as there is currently no known cure.

ADVANCES IN ANATOMIC PATHOLOGY (2021)

Article

Polycystic ovary syndrome and infertility: an update

Mehrukh Zehravi et al.

International Journal of Adolescent Medicine and Health (2021)

Article Multidisciplinary Sciences

The p63 C-terminus is essential for murine oocyte integrity

Anna Maria Lena et al.

Summary: The transcription factor p63 plays a crucial role in regulating cellular responses related to epithelial and oocyte biology. By replacing p63 alpha with p63 beta in a mouse model, researchers demonstrated that this change affects ovary development, mimicking the characteristics of human primary ovary insufficiency.

NATURE COMMUNICATIONS (2021)

Article Genetics & Heredity

Oocyte Elimination Through DNA Damage Signaling from CHK1/CHK2 to p53 and p63

Vera D. Rinaldi et al.

GENETICS (2020)

Article Biochemistry & Molecular Biology

p63 uses a switch-like mechanism to set the threshold for induction of apoptosis

Jakob Gebel et al.

NATURE CHEMICAL BIOLOGY (2020)

Review Biochemistry & Molecular Biology

DNA Damaged Induced Cell Death in Oocytes

Jakob Gebel et al.

MOLECULES (2020)

Article Genetics & Heredity

TP63-truncating variants cause isolated premature ovarian insufficiency

Elena J. Tucker et al.

HUMAN MUTATION (2019)

Article Medicine, General & Internal

Female subfertility

Cynthia M. Farquhar et al.

NATURE REVIEWS DISEASE PRIMERS (2019)

Review Obstetrics & Gynecology

p53 and reproduction

Hey-Joo Kang et al.

FERTILITY AND STERILITY (2018)

Article Biochemistry & Molecular Biology

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63

Marcel Tuppi et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63

Marcel Tuppi et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2018)

Article Obstetrics & Gynecology

The International Glossary on Infertility and Fertility Care, 2017

Fernando Zegers-Hochschild et al.

FERTILITY AND STERILITY (2017)

Review Immunology

Early menopause: A hazard to a woman's health

Claudio Hernandez-Angeles et al.

INDIAN JOURNAL OF MEDICAL RESEARCH (2016)

Article Pharmacology & Pharmacy

Phosphoramide mustard exposure induces DNA adduct formation and the DNA damage repair response in rat ovarian granulosa cells

Shanthi Ganesan et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2015)

Article Obstetrics & Gynecology

Relationship between ovarian cysts and infertility: what surgery and when?

Guillaume Legendre et al.

FERTILITY AND STERILITY (2014)

Article Developmental Biology

PUMA regulates germ cell loss and primordial follicle endowment in mice

Michelle Myers et al.

REPRODUCTION (2014)

Article Multidisciplinary Sciences

Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway

Ewelina Bolcun-Filas et al.

SCIENCE (2014)

Article Pharmacology & Pharmacy

Involvement of a volatile metabolite during phosphoramide mustard-induced ovotoxicity

Jill A. Madden et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2014)

Article Biochemistry & Molecular Biology

Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network

S-Y Kim et al.

CELL DEATH AND DIFFERENTIATION (2013)

Review Cell Biology

p63 the guardian of human reproduction

Ivano Amelio et al.

CELL CYCLE (2012)

Article Cell Biology

TAp63 Is a Master Transcriptional Regulator of Lipid and Glucose Metabolism

Xiaohua Su et al.

CELL METABOLISM (2012)

Article Biochemistry & Molecular Biology

DNA Damage in Oocytes Induces a Switch of the Quality Control Factor TAp63α from Dimer to Tetramer

Gregor B. Deutsch et al.

Article Cell Biology

TAp73 is downregulated in oocytes from women of advanced reproductive age

Maria Rosa Guglielmino et al.

CELL CYCLE (2011)

Article Biochemistry & Molecular Biology

Regulation of female reproduction by p53 and its family members

Zhaohui Feng et al.

FASEB JOURNAL (2011)

Article Cell Biology

The Origins and Evolution of the p53 Family of Genes

Vladimir A. Belyi et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)

Article Cell Biology

The C-terminus of p63 contains multiple regulatory elements with different functions

W. E. Straub et al.

CELL DEATH & DISEASE (2010)

Article Cell & Tissue Engineering

TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance

Xiaohua Su et al.

CELL STEM CELL (2009)

Article Biochemistry & Molecular Biology

Identification and functional characterization of two new transcriptional variants of the human p63 gene

Marina Mangiulli et al.

NUCLEIC ACIDS RESEARCH (2009)

Letter Genetics & Heredity

Limb-mammary syndrome (LMS) associated with internal female genitalia dysgenesia: A new genotype/phenotype correlation?

Laura Guazzarotti et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2008)

Article Developmental Biology

p63 null mutation protects mouse oocytes from radio-induced apoptosis

Gabriel Livera et al.

REPRODUCTION (2008)

Article Biochemistry & Molecular Biology

A new mutation in TP63 is associated with age-related pathology

Muriel Holder-Espinasse et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2007)

Article Multidisciplinary Sciences

p63 protects the female germ line during meiotic arrest

Eun-Kyung Suh et al.

NATURE (2006)

Article Developmental Biology

Differential expression of p63 isoforms in female reproductive organs

T Kurita et al.

MECHANISMS OF DEVELOPMENT (2005)

Article Veterinary Sciences

Expression of p63 in the mouse primordial germ cells

N Nakamuta et al.

JOURNAL OF VETERINARY MEDICAL SCIENCE (2004)

Article Biochemistry & Molecular Biology

The Rapp-Hodgkin syndrome results from mutations of the TP63 gene

G Bougeard et al.

EUROPEAN JOURNAL OF HUMAN GENETICS (2003)

Article Biochemistry & Molecular Biology

A C-terminal inhibitory domain controls the activity of p63 by an intramolecular mechanism

Z Serber et al.

MOLECULAR AND CELLULAR BIOLOGY (2002)