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Colistin Resistance in Aeromonas spp.

Journal

Publisher

MDPI
DOI: 10.3390/ijms22115974

Keywords

colistin; antimicrobial resistance; Aeromonas

Funding

  1. Consejo Nacional de Ciencia y Tecnologia (CONACyT, Mexico)
  2. Sistema Nacional de Investigadores (SNI) from CONACyT, Mexico
  3. Estimulos al Desempeno en Investigacion, Comision y Fomento de Actividades Academicas (Instituto Politecnico Nacional)
  4. Secretaria de Investigacion y Posgrado del Instituto Politecnico Nacional [SIP 20200675, 20211351]

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The increased use of antimicrobials like colistin has led to the emergence of colistin-resistant Aeromonas strains. These strains have been found not only in clinical settings, but also in environmental and animal isolates, identified by detection of mcr genes. Different mcr variants have been detected in Aeromonas from various sources, including animals, environments, and human samples. This article provides an overview of colistin resistance in Aeromonas, along with general characteristics of the molecule and recommended methods for determining colistin resistance in certain Aeromonas species.
The increase in the use of antimicrobials such as colistin for the treatment of infectious diseases has led to the appearance of Aeromonas strains resistant to this drug. However, resistance to colistin not only occurs in the clinical area but has also been determined in Aeromonas isolates from the environment or animals, which has been determined by the detection of mcr genes that confer a resistance mechanism to colistin. The variants mcr-1, mcr-3, and mcr-5 have been detected in the genus Aeromonas in animal, environmental, and human fluids samples. In this article, an overview of the resistance to colistin in Aeromonas is shown, as well as the generalities of this molecule and the recommended methods to determine colistin resistance to be used in some of the genus Aeromonas.

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